2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide

C128H153BrClF3N24O10 — CID 161280261

About 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide

2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide (PubChem CID 161280261) has the molecular formula C128H153BrClF3N24O10 and a molecular weight of 2360.14 g/mol. Its IUPAC name is 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide.

Molecular Properties

• Compound Name: 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide
• PubChem CID: 161280261
• Molecular Formula: C128H153BrClF3N24O10
• Molecular Weight: 2360.14 g/mol
• Exact Mass: 2357.10
• IUPAC Name: 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide
• SMILES: CN1C(=O)C(c2cccc(-c3cncc(Br)c3)c2)(C2CC2)N=C1N.CN1C(=O)[C@@](CCC2CCCCC2)(C[C@H]2CCC[C@@H](NC(=O)c3ccc(C(F)(F)F)nc3)C2)N=C1N.COc1cc(C(=O)N[C@@H]2CCC[C@H](C[C@@]3(CCC4CCCCC4)N=C(N)N(C)C3=O)C2)cc(Cl)n1.Cc1ccccc1NC(=O)N1CCC(CN2C(=O)C(c3ccccc3)(c3ccccc3)N=C2N)CC1.NC1=NC(c2ccccc2)(c2ccccc2)C(=O)N1CC1CCN(C(=O)CNc2ccccc2)CC1
• InChI: InChI=1S/2C29H31N5O2.C26H38ClN5O3.C26H36F3N5O2.C18H17BrN4O/c1-21-10-8-9-15-25(21)31-28(36)33-18-16-22(17-19-33)20-34-26(35)29(32-27(34)30,23-11-4-2-5-12-23)24-13-6-3-7-14-24;30-28-32-29(23-10-4-1-5-11-23,24-12-6-2-7-13-24)27(36)34(28)21-22-16-18-33(19-17-22)26(35)20-31-25-14-8-3-9-15-25;1-32-24(34)26(31-25(32)28,12-11-17-7-4-3-5-8-17)16-18-9-6-10-20(13-18)29-23(33)19-14-21(27)30-22(15-19)35-2;1-34-23(36)25(33-24(34)30,13-12-17-6-3-2-4-7-17)15-18-8-5-9-20(14-18)32-22(35)19-10-11-21(31-16-19)26(27,28)29;1-23-16(24)18(13-5-6-13,22-17(23)20)14-4-2-3-11(7-14)12-8-15(19)10-21-9-12/h2-15,22H,16-20H2,1H3,(H2,30,32)(H,31,36);1-15,22,31H,16-21H2,(H2,30,32);14-15,17-18,20H,3-13,16H2,1-2H3,(H2,28,31)(H,29,33);10-11,16-18,20H,2-9,12-15H2,1H3,(H2,30,33)(H,32,35);2-4,7-10,13H,5-6H2,1H3,(H2,20,22)/t;;18-,20+,26+;18-,20+,25+;/m..00./s1
• InChIKey: VEZFXDVDMPQKQG-DBAGXMCMSA-N
• XLogP: 19.65
• TPSA: 464.23 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 24
• Rotatable Bonds: 30
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2360.14
LogP ≤ 5	19.65
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	24

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide?

The IUPAC name of 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide (CID 161280261) is 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide.

What is the SMILES notation for 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide?

The canonical SMILES for 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide is CN1C(=O)C(c2cccc(-c3cncc(Br)c3)c2)(C2CC2)N=C1N.CN1C(=O)[C@@](CCC2CCCCC2)(C[C@H]2CCC[C@@H](NC(=O)c3ccc(C(F)(F)F)nc3)C2)N=C1N.COc1cc(C(=O)N[C@@H]2CCC[C@H](C[C@@]3(CCC4CCCCC4)N=C(N)N(C)C3=O)C2)cc(Cl)n1.Cc1ccccc1NC(=O)N1CCC(CN2C(=O)C(c3ccccc3)(c3ccccc3)N=C2N)CC1.NC1=NC(c2ccccc2)(c2ccccc2)C(=O)N1CC1CCN(C(=O)CNc2ccccc2)CC1.

What is the InChIKey of 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide?

The InChIKey is VEZFXDVDMPQKQG-DBAGXMCMSA-N. The full InChI is InChI=1S/2C29H31N5O2.C26H38ClN5O3.C26H36F3N5O2.C18H17BrN4O/c1-21-10-8-9-15-25(21)31-28(36)33-18-16-22(17-19-33)20-34-26(35)29(32-27(34)30,23-11-4-2-5-12-23)24-13-6-3-7-14-24;30-28-32-29(23-10-4-1-5-11-23,24-12-6-2-7-13-24)27(36)34(28)21-22-16-18-33(19-17-22)26(35)20-31-25-14-8-3-9-15-25;1-32-24(34)26(31-25(32)28,12-11-17-7-4-3-5-8-17)16-18-9-6-10-20(13-18)29-23(33)19-14-21(27)30-22(15-19)35-2;1-34-23(36)25(33-24(34)30,13-12-17-6-3-2-4-7-17)15-18-8-5-9-20(14-18)32-22(35)19-10-11-21(31-16-19)26(27,28)29;1-23-16(24)18(13-5-6-13,22-17(23)20)14-4-2-3-11(7-14)12-8-15(19)10-21-9-12/h2-15,22H,16-20H2,1H3,(H2,30,32)(H,31,36);1-15,22,31H,16-21H2,(H2,30,32);14-15,17-18,20H,3-13,16H2,1-2H3,(H2,28,31)(H,29,33);10-11,16-18,20H,2-9,12-15H2,1H3,(H2,30,33)(H,32,35);2-4,7-10,13H,5-6H2,1H3,(H2,20,22)/t;;18-,20+,26+;18-,20+,25+;/m..00./s1.

What are the key properties of 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide?

2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide has a molecular weight of 2360.14 g/mol, XLogP of 19.65, 30 rotatable bonds, 9 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-3-[[1-(2-anilinoacetyl)piperidin-4-yl]methyl]-5,5-diphenylimidazol-4-one;2-amino-5-[3-(5-bromo-3-pyridinyl)phenyl]-5-cyclopropyl-3-methylimidazol-4-one;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-2-chloro-6-methoxypyridine-4-carboxamide;N-[(1R,3S)-3-[[(4R)-2-amino-4-(2-cyclohexylethyl)-1-methyl-5-oxoimidazol-4-yl]methyl]cyclohexyl]-6-(trifluoromethyl)pyridine-3-carboxamide;4-[(2-amino-5-oxo-4,4-diphenylimidazol-1-yl)methyl]-N-(2-methylphenyl)piperidine-1-carboxamide is sourced from PubChem (CID 161280261), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).