[1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone

C145H163ClF8N16O21 — CID 161301844

About [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone

[1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone (PubChem CID 161301844) has the molecular formula C145H163ClF8N16O21 and a molecular weight of 2653.43 g/mol. Its IUPAC name is [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone.

Molecular Properties

• Compound Name: [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone
• PubChem CID: 161301844
• Molecular Formula: C145H163ClF8N16O21
• Molecular Weight: 2653.43 g/mol
• Exact Mass: 2651.17
• IUPAC Name: [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone
• SMILES: COc1cc2c(cc1OC(C)C)-n1c(-c3cc(F)ccc3F)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(C#N)c(C(F)(F)F)c3)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(C)c(F)c3)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(F)c(Cl)c3F)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1ccc(-c2nc(C(=O)N3CCOCC3(C)C)c3n2-c2cc(OC(C)C)c(OC)cc2CC3)cc1C
• InChI: InChI=1S/C30H31F3N4O4.C30H37N3O5.C29H34FN3O4.C28H30ClF2N3O4.C28H31F2N3O4/c1-17(2)41-25-14-23-18(13-24(25)39-5)8-9-22-26(28(38)36-10-11-40-16-29(36,3)4)35-27(37(22)23)19-6-7-20(15-34)21(12-19)30(31,32)33;1-18(2)38-26-16-23-20(15-25(26)36-7)8-10-22-27(29(34)32-12-13-37-17-30(32,4)5)31-28(33(22)23)21-9-11-24(35-6)19(3)14-21;1-17(2)37-25-15-23-19(14-24(25)35-6)9-10-22-26(28(34)32-11-12-36-16-29(32,4)5)31-27(33(22)23)20-8-7-18(3)21(30)13-20;1-15(2)38-22-13-20-16(12-21(22)36-5)6-9-19-25(27(35)33-10-11-37-14-28(33,3)4)32-26(34(19)20)17-7-8-18(30)23(29)24(17)31;1-16(2)37-24-14-22-17(12-23(24)35-5)6-9-21-25(27(34)32-10-11-36-15-28(32,3)4)31-26(33(21)22)19-13-18(29)7-8-20(19)30/h6-7,12-14,17H,8-11,16H2,1-5H3;9,11,14-16,18H,8,10,12-13,17H2,1-7H3;7-8,13-15,17H,9-12,16H2,1-6H3;7-8,12-13,15H,6,9-11,14H2,1-5H3;7-8,12-14,16H,6,9-11,15H2,1-5H3
• InChIKey: VHSMTGUSNNBEAI-UHFFFAOYSA-N
• XLogP: 26.29
• TPSA: 362.12 Ų
• H-Bond Acceptors: 32
• Rotatable Bonds: 26
• Heavy Atoms: 191
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2653.43
LogP ≤ 5	26.29
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	32

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'halogenated_ring_2', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone?

The IUPAC name of [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone (CID 161301844) is [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone.

What is the SMILES notation for [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone?

The canonical SMILES for [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone is COc1cc2c(cc1OC(C)C)-n1c(-c3cc(F)ccc3F)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(C#N)c(C(F)(F)F)c3)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(C)c(F)c3)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1cc2c(cc1OC(C)C)-n1c(-c3ccc(F)c(Cl)c3F)nc(C(=O)N3CCOCC3(C)C)c1CC2.COc1ccc(-c2nc(C(=O)N3CCOCC3(C)C)c3n2-c2cc(OC(C)C)c(OC)cc2CC3)cc1C.

What is the InChIKey of [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone?

The InChIKey is VHSMTGUSNNBEAI-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H31F3N4O4.C30H37N3O5.C29H34FN3O4.C28H30ClF2N3O4.C28H31F2N3O4/c1-17(2)41-25-14-23-18(13-24(25)39-5)8-9-22-26(28(38)36-10-11-40-16-29(36,3)4)35-27(37(22)23)19-6-7-20(15-34)21(12-19)30(31,32)33;1-18(2)38-26-16-23-20(15-25(26)36-7)8-10-22-27(29(34)32-12-13-37-17-30(32,4)5)31-28(33(22)23)21-9-11-24(35-6)19(3)14-21;1-17(2)37-25-15-23-19(14-24(25)35-6)9-10-22-26(28(34)32-11-12-36-16-29(32,4)5)31-27(33(22)23)20-8-7-18(3)21(30)13-20;1-15(2)38-22-13-20-16(12-21(22)36-5)6-9-19-25(27(35)33-10-11-37-14-28(33,3)4)32-26(34(19)20)17-7-8-18(30)23(29)24(17)31;1-16(2)37-24-14-22-17(12-23(24)35-5)6-9-21-25(27(34)32-10-11-36-15-28(32,3)4)31-26(33(21)22)19-13-18(29)7-8-20(19)30/h6-7,12-14,17H,8-11,16H2,1-5H3;9,11,14-16,18H,8,10,12-13,17H2,1-7H3;7-8,13-15,17H,9-12,16H2,1-6H3;7-8,12-13,15H,6,9-11,14H2,1-5H3;7-8,12-14,16H,6,9-11,15H2,1-5H3.

What are the key properties of [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone?

[1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone has a molecular weight of 2653.43 g/mol, XLogP of 26.29, 26 rotatable bonds, 0 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for [1-(3-chloro-2,4-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;[1-(2,5-difluorophenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]-(3,3-dimethylmorpholin-4-yl)methanone;4-[3-(3,3-dimethylmorpholine-4-carbonyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-1-yl]-2-(trifluoromethyl)benzonitrile;(3,3-dimethylmorpholin-4-yl)-[1-(3-fluoro-4-methylphenyl)-7-methoxy-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone;(3,3-dimethylmorpholin-4-yl)-[7-methoxy-1-(4-methoxy-3-methylphenyl)-8-propan-2-yloxy-4,5-dihydroimidazo[1,5-a]quinolin-3-yl]methanone is sourced from PubChem (CID 161301844), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).