N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid

C128H123F7N30O19 — CID 161316814

About N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid

N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid (PubChem CID 161316814) has the molecular formula C128H123F7N30O19 and a molecular weight of 2518.57 g/mol. Its IUPAC name is N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid.

Molecular Properties

• Compound Name: N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid
• PubChem CID: 161316814
• Molecular Formula: C128H123F7N30O19
• Molecular Weight: 2518.57 g/mol
• Exact Mass: 2516.95
• IUPAC Name: N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid
• SMILES: COC(=O)Cn1cc(-c2ccccc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O.O=C(Nc1cc(-c2ccccc2)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(Nc1cc(-c2ccccc2)cn(CC2CC2)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(Nc1cc(-c2ccccc2F)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(O)Cn1cc(-c2ccccc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O
• InChI: InChI=1S/C27H28N6O3.C26H26N6O5.C25H22F4N6O3.C25H23F3N6O3.C25H24N6O5/c34-25-22(15-20(19-5-2-1-3-6-19)17-32(25)16-18-8-9-18)29-26(35)31-13-10-21(11-14-31)33-23-7-4-12-28-24(23)30-27(33)36;1-37-22(33)16-31-15-18(17-6-3-2-4-7-17)14-20(24(31)34)28-25(35)30-12-9-19(10-13-30)32-21-8-5-11-27-23(21)29-26(32)36;26-18-5-2-1-4-17(18)15-12-19(22(36)34(13-15)14-25(27,28)29)31-23(37)33-10-7-16(8-11-33)35-20-6-3-9-30-21(20)32-24(35)38;26-25(27,28)15-33-14-17(16-5-2-1-3-6-16)13-19(22(33)35)30-23(36)32-11-8-18(9-12-32)34-20-7-4-10-29-21(20)31-24(34)37;32-21(33)15-30-14-17(16-5-2-1-3-6-16)13-19(23(30)34)27-24(35)29-11-8-18(9-12-29)31-20-7-4-10-26-22(20)28-25(31)36/h1-7,12,15,17-18,21H,8-11,13-14,16H2,(H,29,35)(H,28,30,36);2-8,11,14-15,19H,9-10,12-13,16H2,1H3,(H,28,35)(H,27,29,36);1-6,9,12-13,16H,7-8,10-11,14H2,(H,31,37)(H,30,32,38);1-7,10,13-14,18H,8-9,11-12,15H2,(H,30,36)(H,29,31,37);1-7,10,13-14,18H,8-9,11-12,15H2,(H,27,35)(H,32,33)(H,26,28,36)
• InChIKey: VJPKCEKDDOUFBI-UHFFFAOYSA-N
• XLogP: 17.04
• TPSA: 588.70 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 33
• Rotatable Bonds: 23
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2518.57
LogP ≤ 5	17.04
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid?

The IUPAC name of N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid (CID 161316814) is N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid.

What is the SMILES notation for N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid?

The canonical SMILES for N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid is COC(=O)Cn1cc(-c2ccccc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O.O=C(Nc1cc(-c2ccccc2)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(Nc1cc(-c2ccccc2)cn(CC2CC2)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(Nc1cc(-c2ccccc2F)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(O)Cn1cc(-c2ccccc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O.

What is the InChIKey of N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid?

The InChIKey is VJPKCEKDDOUFBI-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H28N6O3.C26H26N6O5.C25H22F4N6O3.C25H23F3N6O3.C25H24N6O5/c34-25-22(15-20(19-5-2-1-3-6-19)17-32(25)16-18-8-9-18)29-26(35)31-13-10-21(11-14-31)33-23-7-4-12-28-24(23)30-27(33)36;1-37-22(33)16-31-15-18(17-6-3-2-4-7-17)14-20(24(31)34)28-25(35)30-12-9-19(10-13-30)32-21-8-5-11-27-23(21)29-26(32)36;26-18-5-2-1-4-17(18)15-12-19(22(36)34(13-15)14-25(27,28)29)31-23(37)33-10-7-16(8-11-33)35-20-6-3-9-30-21(20)32-24(35)38;26-25(27,28)15-33-14-17(16-5-2-1-3-6-16)13-19(22(33)35)30-23(36)32-11-8-18(9-12-32)34-20-7-4-10-29-21(20)31-24(34)37;32-21(33)15-30-14-17(16-5-2-1-3-6-16)13-19(23(30)34)27-24(35)29-11-8-18(9-12-29)31-20-7-4-10-26-22(20)28-25(31)36/h1-7,12,15,17-18,21H,8-11,13-14,16H2,(H,29,35)(H,28,30,36);2-8,11,14-15,19H,9-10,12-13,16H2,1H3,(H,28,35)(H,27,29,36);1-6,9,12-13,16H,7-8,10-11,14H2,(H,31,37)(H,30,32,38);1-7,10,13-14,18H,8-9,11-12,15H2,(H,30,36)(H,29,31,37);1-7,10,13-14,18H,8-9,11-12,15H2,(H,27,35)(H,32,33)(H,26,28,36).

What are the key properties of N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid?

N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid has a molecular weight of 2518.57 g/mol, XLogP of 17.04, 23 rotatable bonds, 11 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for N-[1-(cyclopropylmethyl)-2-oxo-5-phenyl-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;N-[5-(2-fluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-3-pyridinyl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide;methyl 2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetate;4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-pyridinyl]piperidine-1-carboxamide;2-[2-oxo-3-[[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carbonyl]amino]-5-phenyl-1-pyridinyl]acetic acid is sourced from PubChem (CID 161316814), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).