2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one

C195H136F41N51O14S3 — CID 161331998

IUPAC2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one
SMILESCN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccn[nH]3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccoc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccon3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccsc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnc(F)nc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnco3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncs3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cocn3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cscn3)c2)N=C1N.Cc1ncc(-c2cc(C3(c4ccnc(C(F)(F)F)c4)N=C(N)N(C)C3=O)ccc2F)cn1
InChIInChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H14F4N6O.3C19H13F4N5O2.2C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)14-5-6-27-17(8-14)21(23,24)25;1-31-16(32)19(30-18(31)26,12-4-5-27-15(7-12)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,13-4-6-26-16(9-13)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;1-29-16(30)18(27-17(29)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-26-28-14;1-28-16(29)18(26-17(28)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-30-27-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2-9H,1H3,(H2,24,27)(H,26,28);2-9H,1H3,(H2,24,26);4*2-9H,1H3,(H2,24,27)
InChIKeyVLNQTRVOVCWRDM-UHFFFAOYSA-N
MW4292.69 g/mol
LogP31.65
Rot. Bonds30

About 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one

2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one (PubChem CID 161331998) has the molecular formula C195H136F41N51O14S3 and a molecular weight of 4292.69 g/mol. Its IUPAC name is 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one.

Molecular Properties

Compound Name2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one
PubChem CID161331998
Molecular FormulaC195H136F41N51O14S3
Molecular Weight4292.69 g/mol
Exact Mass4290.00
IUPAC Name2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one
SMILESCN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccn[nH]3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccoc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccon3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccsc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnc(F)nc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnco3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncs3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cocn3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cscn3)c2)N=C1N.Cc1ncc(-c2cc(C3(c4ccnc(C(F)(F)F)c4)N=C(N)N(C)C3=O)ccc2F)cn1
InChIInChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H14F4N6O.3C19H13F4N5O2.2C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)14-5-6-27-17(8-14)21(23,24)25;1-31-16(32)19(30-18(31)26,12-4-5-27-15(7-12)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,13-4-6-26-16(9-13)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;1-29-16(30)18(27-17(29)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-26-28-14;1-28-16(29)18(26-17(28)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-30-27-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2-9H,1H3,(H2,24,27)(H,26,28);2-9H,1H3,(H2,24,26);4*2-9H,1H3,(H2,24,27)
InChIKeyVLNQTRVOVCWRDM-UHFFFAOYSA-N
XLogP31.65
TPSA913.05 Ų
H-Bond Donors11
H-Bond Acceptors57
Rotatable Bonds30
Heavy Atoms304
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004292.69
LogP ≤ 531.65
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1057

Analyze 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one?
The IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one (CID 161331998) is 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one.
What is the SMILES notation for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one?
The canonical SMILES for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one is CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccn[nH]3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccoc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccon3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3ccsc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnc(F)nc3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnco3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncs3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cocn3)c2)N=C1N.CN1C(=O)C(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cscn3)c2)N=C1N.Cc1ncc(-c2cc(C3(c4ccnc(C(F)(F)F)c4)N=C(N)N(C)C3=O)ccc2F)cn1.
What is the InChIKey of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one?
The InChIKey is VLNQTRVOVCWRDM-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H14F4N6O.3C19H13F4N5O2.2C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)14-5-6-27-17(8-14)21(23,24)25;1-31-16(32)19(30-18(31)26,12-4-5-27-15(7-12)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,13-4-6-26-16(9-13)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;1-29-16(30)18(27-17(29)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-26-28-14;1-28-16(29)18(26-17(28)24,11-4-6-25-15(9-11)19(21,22)23)10-2-3-13(20)12(8-10)14-5-7-30-27-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14;1-28-16(29)18(27-17(28)24,11-4-5-26-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-25-9-30-14;1-28-16(29)18(27-17(28)24,11-4-5-25-15(7-11)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2-9H,1H3,(H2,24,27)(H,26,28);2-9H,1H3,(H2,24,26);4*2-9H,1H3,(H2,24,27).
What are the key properties of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one?
2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one has a molecular weight of 4292.69 g/mol, XLogP of 31.65, 30 rotatable bonds, 11 hydrogen bond donors, and 57 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,2-oxazol-3-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1H-pyrazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one is sourced from PubChem (CID 161331998), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).