1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine

C88H96F10N38O11S5 — CID 161337329

About 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine

1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine (PubChem CID 161337329) has the molecular formula C88H96F10N38O11S5 and a molecular weight of 2212.31 g/mol. Its IUPAC name is 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine.

Molecular Properties

• Compound Name: 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine
• PubChem CID: 161337329
• Molecular Formula: C88H96F10N38O11S5
• Molecular Weight: 2212.31 g/mol
• Exact Mass: 2210.66
• IUPAC Name: 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine
• SMILES: CS(=O)(=O)N1CC2CCN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2C1.NS(=O)(=O)CCC1CCCCN1c1cc(-c2cnc3ccc(C(F)F)nn23)ncn1.NS(=O)(=O)N1CC2CCN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2C1.NS(=O)(=O)N1CCCC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2)C1.NS(=O)(=O)N1CCOC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2)C1
• InChI: InChI=1S/C18H20F2N8O2S.C18H19F2N7O2S.C18H21F2N7O2S.C17H18F2N8O3S.C17H18F2N8O2S/c19-17(20)12-2-3-15-22-7-14(28(15)25-12)13-6-16(24-11-23-13)26-8-18(9-26)4-1-5-27(10-18)31(21,29)30;1-30(28,29)25-8-11-4-5-26(15(11)9-25)17-6-13(22-10-23-17)14-7-21-16-3-2-12(18(19)20)24-27(14)16;19-18(20)13-4-5-16-22-10-15(27(16)25-13)14-9-17(24-11-23-14)26-7-2-1-3-12(26)6-8-30(21,28)29;18-16(19)11-1-2-14-21-6-13(27(14)24-11)12-5-15(23-10-22-12)25-7-17(8-25)9-26(3-4-30-17)31(20,28)29;18-17(19)11-1-2-15-21-6-13(27(15)24-11)12-5-16(23-9-22-12)26-4-3-10-7-25(8-14(10)26)30(20,28)29/h2-3,6-7,11,17H,1,4-5,8-10H2,(H2,21,29,30);2-3,6-7,10-11,15,18H,4-5,8-9H2,1H3;4-5,9-12,18H,1-3,6-8H2,(H2,21,28,29);1-2,5-6,10,16H,3-4,7-9H2,(H2,20,28,29);1-2,5-6,9-10,14,17H,3-4,7-8H2,(H2,20,28,29)
• InChIKey: VMFAUFBFGWWPKB-UHFFFAOYSA-N
• XLogP: 6.04
• TPSA: 593.02 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 41
• Rotatable Bonds: 22
• Heavy Atoms: 152
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2212.31
LogP ≤ 5	6.04
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine?

The IUPAC name of 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine (CID 161337329) is 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine.

What is the SMILES notation for 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine?

The canonical SMILES for 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine is CS(=O)(=O)N1CC2CCN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2C1.NS(=O)(=O)CCC1CCCCN1c1cc(-c2cnc3ccc(C(F)F)nn23)ncn1.NS(=O)(=O)N1CC2CCN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2C1.NS(=O)(=O)N1CCCC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2)C1.NS(=O)(=O)N1CCOC2(CN(c3cc(-c4cnc5ccc(C(F)F)nn45)ncn3)C2)C1.

What is the InChIKey of 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine?

The InChIKey is VMFAUFBFGWWPKB-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20F2N8O2S.C18H19F2N7O2S.C18H21F2N7O2S.C17H18F2N8O3S.C17H18F2N8O2S/c19-17(20)12-2-3-15-22-7-14(28(15)25-12)13-6-16(24-11-23-13)26-8-18(9-26)4-1-5-27(10-18)31(21,29)30;1-30(28,29)25-8-11-4-5-26(15(11)9-25)17-6-13(22-10-23-17)14-7-21-16-3-2-12(18(19)20)24-27(14)16;19-18(20)13-4-5-16-22-10-15(27(16)25-13)14-9-17(24-11-23-14)26-7-2-1-3-12(26)6-8-30(21,28)29;18-16(19)11-1-2-14-21-6-13(27(14)24-11)12-5-15(23-10-22-12)25-7-17(8-25)9-26(3-4-30-17)31(20,28)29;18-17(19)11-1-2-15-21-6-13(27(15)24-11)12-5-16(23-9-22-12)26-4-3-10-7-25(8-14(10)26)30(20,28)29/h2-3,6-7,11,17H,1,4-5,8-10H2,(H2,21,29,30);2-3,6-7,10-11,15,18H,4-5,8-9H2,1H3;4-5,9-12,18H,1-3,6-8H2,(H2,21,28,29);1-2,5-6,10,16H,3-4,7-9H2,(H2,20,28,29);1-2,5-6,9-10,14,17H,3-4,7-8H2,(H2,20,28,29).

What are the key properties of 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine?

1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine has a molecular weight of 2212.31 g/mol, XLogP of 6.04, 22 rotatable bonds, 4 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-5-oxa-2,8-diazaspiro[3.5]nonane-8-sulfonamide;2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]piperidin-2-yl]ethanesulfonamide;6-(difluoromethyl)-3-[6-(5-methylsulfonyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine is sourced from PubChem (CID 161337329), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).