8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone

C132H139Cl5F4N16O8 — CID 161352709

About 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone

8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone (PubChem CID 161352709) has the molecular formula C132H139Cl5F4N16O8 and a molecular weight of 2330.92 g/mol. Its IUPAC name is 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone.

Molecular Properties

• Compound Name: 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone
• PubChem CID: 161352709
• Molecular Formula: C132H139Cl5F4N16O8
• Molecular Weight: 2330.92 g/mol
• Exact Mass: 2326.93
• IUPAC Name: 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone
• SMILES: CC(F)(F)c1ccc(C(=O)N2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1F.Cc1ccc(C(=O)N2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.Cc1ccc2[nH]c(C(=O)N3CC4CCCN(Cc5ccc(F)cc5)C4C3)cc2c1.Cc1cccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)c1.O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCC2(CCC2)CC1.O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCC2(CCCC2)CC1
• InChI: InChI=1S/C25H23ClF3N3O2.C24H24ClN3O2.C24H26ClN3O.C24H26FN3O.C18H21ClN2O.C17H19ClN2O/c1-24(28,29)18-4-2-15(11-19(18)27)22(33)32-13-25(14-32)6-8-31(9-7-25)23(34)21-12-16-10-17(26)3-5-20(16)30-21;1-16-2-4-17(5-3-16)22(29)28-14-24(15-28)8-10-27(11-9-24)23(30)21-13-18-12-19(25)6-7-20(18)26-21;1-17-3-2-4-18(11-17)14-27-15-24(16-27)7-9-28(10-8-24)23(29)22-13-19-12-20(25)5-6-21(19)26-22;1-16-4-9-21-19(11-16)12-22(26-21)24(29)28-14-18-3-2-10-27(23(18)15-28)13-17-5-7-20(25)8-6-17;19-14-3-4-15-13(11-14)12-16(20-15)17(22)21-9-7-18(8-10-21)5-1-2-6-18;18-13-2-3-14-12(10-13)11-15(19-14)16(21)20-8-6-17(7-9-20)4-1-5-17/h2-5,10-12,30H,6-9,13-14H2,1H3;2-7,12-13,26H,8-11,14-15H2,1H3;2-6,11-13,26H,7-10,14-16H2,1H3;4-9,11-12,18,23,26H,2-3,10,13-15H2,1H3;3-4,11-12,20H,1-2,5-10H2;2-3,10-11,19H,1,4-9H2
• InChIKey: VODARXFKQOQWIL-UHFFFAOYSA-N
• XLogP: 28.02
• TPSA: 263.70 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 10
• Rotatable Bonds: 13
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2330.92
LogP ≤ 5	28.02
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	10

Frequently Asked Questions

What is the IUPAC name of 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone?

The IUPAC name of 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone (CID 161352709) is 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone.

What is the SMILES notation for 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone?

The canonical SMILES for 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone is CC(F)(F)c1ccc(C(=O)N2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1F.Cc1ccc(C(=O)N2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)cc1.Cc1ccc2[nH]c(C(=O)N3CC4CCCN(Cc5ccc(F)cc5)C4C3)cc2c1.Cc1cccc(CN2CC3(CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)CC3)C2)c1.O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCC2(CCC2)CC1.O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCC2(CCCC2)CC1.

What is the InChIKey of 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone?

The InChIKey is VODARXFKQOQWIL-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H23ClF3N3O2.C24H24ClN3O2.C24H26ClN3O.C24H26FN3O.C18H21ClN2O.C17H19ClN2O/c1-24(28,29)18-4-2-15(11-19(18)27)22(33)32-13-25(14-32)6-8-31(9-7-25)23(34)21-12-16-10-17(26)3-5-20(16)30-21;1-16-2-4-17(5-3-16)22(29)28-14-24(15-28)8-10-27(11-9-24)23(30)21-13-18-12-19(25)6-7-20(18)26-21;1-17-3-2-4-18(11-17)14-27-15-24(16-27)7-9-28(10-8-24)23(29)22-13-19-12-20(25)5-6-21(19)26-22;1-16-4-9-21-19(11-16)12-22(26-21)24(29)28-14-18-3-2-10-27(23(18)15-28)13-17-5-7-20(25)8-6-17;19-14-3-4-15-13(11-14)12-16(20-15)17(22)21-9-7-18(8-10-21)5-1-2-6-18;18-13-2-3-14-12(10-13)11-15(19-14)16(21)20-8-6-17(7-9-20)4-1-5-17/h2-5,10-12,30H,6-9,13-14H2,1H3;2-7,12-13,26H,8-11,14-15H2,1H3;2-6,11-13,26H,7-10,14-16H2,1H3;4-9,11-12,18,23,26H,2-3,10,13-15H2,1H3;3-4,11-12,20H,1-2,5-10H2;2-3,10-11,19H,1,4-9H2.

What are the key properties of 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone?

8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone has a molecular weight of 2330.92 g/mol, XLogP of 28.02, 13 rotatable bonds, 6 hydrogen bond donors, and 10 hydrogen bond acceptors.

Where does this data come from?

All data for 8-azaspiro[4.5]decan-8-yl-(5-chloro-1H-indol-2-yl)methanone;7-azaspiro[3.5]nonan-7-yl-(5-chloro-1H-indol-2-yl)methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-[4-(1,1-difluoroethyl)-3-fluorophenyl]methanone;[7-(5-chloro-1H-indole-2-carbonyl)-2,7-diazaspiro[3.5]nonan-2-yl]-(4-methylphenyl)methanone;(5-chloro-1H-indol-2-yl)-[2-[(3-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;[1-[(4-fluorophenyl)methyl]-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridin-6-yl]-(5-methyl-1H-indol-2-yl)methanone is sourced from PubChem (CID 161352709), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).