3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate

C279H337F9N44O25 — CID 161368701

IUPAC3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(F)(F)F)cn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(OC(F)(F)F)cc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)NCC3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)OCO3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc3ncccc13)C(=O)N2.COC(=O)c1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COC(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cc1.COC(=O)c1cccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)c1.COC(=O)c1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.COc1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C25H28N4O.C24H30N4O3.C24H30N4O.3C24H29N3O3.C23H26F3N3O2.C23H30N4O2.C23H27N3O3.C22H25F3N4O.C22H28N4O2.C21H26F3N5O/c1-28(2)25(19-8-4-3-5-9-19)15-13-24(14-16-25)18-29(23(30)27-24)22-12-6-11-21-20(22)10-7-17-26-21;1-17-14-19(21(29)31-4)25-15-20(17)28-16-23(26-22(28)30)10-12-24(13-11-23,27(2)3)18-8-6-5-7-9-18;1-27(2)24(19-6-4-3-5-7-19)13-11-23(12-14-24)17-28(22(29)26-23)20-9-8-18-10-15-25-21(18)16-20;1-26(2)24(19-9-5-4-6-10-19)14-12-23(13-15-24)17-27(22(29)25-23)20-11-7-8-18(16-20)21(28)30-3;1-26(2)24(18-9-5-4-6-10-18)15-13-23(14-16-24)17-27(22(29)25-23)20-12-8-7-11-19(20)21(28)30-3;1-26(2)24(19-7-5-4-6-8-19)15-13-23(14-16-24)17-27(22(29)25-23)20-11-9-18(10-12-20)21(28)30-3;1-28(2)22(17-6-4-3-5-7-17)14-12-21(13-15-22)16-29(20(30)27-21)18-8-10-19(11-9-18)31-23(24,25)26;1-17-14-20(29-4)24-15-19(17)27-16-22(25-21(27)28)10-12-23(13-11-22,26(2)3)18-8-6-5-7-9-18;1-25(2)23(17-6-4-3-5-7-17)12-10-22(11-13-23)15-26(21(27)24-22)18-8-9-19-20(14-18)29-16-28-19;1-28(2)21(16-6-4-3-5-7-16)12-10-20(11-13-21)15-29(19(30)27-20)18-9-8-17(14-26-18)22(23,24)25;1-25(2)22(17-8-5-4-6-9-17)13-11-21(12-14-22)16-26(20(27)24-21)19-18(28-3)10-7-15-23-19;1-27(2)20(15-7-5-4-6-8-15)11-9-19(10-12-20)14-29(18(30)25-19)17-13-16(21(22,23)24)26-28(17)3/h3-12,17H,13-16,18H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,26,30);3-9,16,25H,10-15,17H2,1-2H3,(H,26,29);4-11,16H,12-15,17H2,1-3H3,(H,25,29);2*4-12H,13-17H2,1-3H3,(H,25,29);3-11H,12-16H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,25,28);3-9,14H,10-13,15-16H2,1-2H3,(H,24,27);3-9,14H,10-13,15H2,1-2H3,(H,27,30);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-8,13H,9-12,14H2,1-3H3,(H,25,30)
InChIKeyVQEDXWXUHNXCPE-UHFFFAOYSA-N
MW4878.03 g/mol
LogP47.11
Rot. Bonds43

About 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate

3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate (PubChem CID 161368701) has the molecular formula C279H337F9N44O25 and a molecular weight of 4878.03 g/mol. Its IUPAC name is 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate.

Molecular Properties

Compound Name3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate
PubChem CID161368701
Molecular FormulaC279H337F9N44O25
Molecular Weight4878.03 g/mol
Exact Mass4874.63
IUPAC Name3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(F)(F)F)cn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(OC(F)(F)F)cc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)NCC3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)OCO3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc3ncccc13)C(=O)N2.COC(=O)c1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COC(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cc1.COC(=O)c1cccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)c1.COC(=O)c1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.COc1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C25H28N4O.C24H30N4O3.C24H30N4O.3C24H29N3O3.C23H26F3N3O2.C23H30N4O2.C23H27N3O3.C22H25F3N4O.C22H28N4O2.C21H26F3N5O/c1-28(2)25(19-8-4-3-5-9-19)15-13-24(14-16-25)18-29(23(30)27-24)22-12-6-11-21-20(22)10-7-17-26-21;1-17-14-19(21(29)31-4)25-15-20(17)28-16-23(26-22(28)30)10-12-24(13-11-23,27(2)3)18-8-6-5-7-9-18;1-27(2)24(19-6-4-3-5-7-19)13-11-23(12-14-24)17-28(22(29)26-23)20-9-8-18-10-15-25-21(18)16-20;1-26(2)24(19-9-5-4-6-10-19)14-12-23(13-15-24)17-27(22(29)25-23)20-11-7-8-18(16-20)21(28)30-3;1-26(2)24(18-9-5-4-6-10-18)15-13-23(14-16-24)17-27(22(29)25-23)20-12-8-7-11-19(20)21(28)30-3;1-26(2)24(19-7-5-4-6-8-19)15-13-23(14-16-24)17-27(22(29)25-23)20-11-9-18(10-12-20)21(28)30-3;1-28(2)22(17-6-4-3-5-7-17)14-12-21(13-15-22)16-29(20(30)27-21)18-8-10-19(11-9-18)31-23(24,25)26;1-17-14-20(29-4)24-15-19(17)27-16-22(25-21(27)28)10-12-23(13-11-22,26(2)3)18-8-6-5-7-9-18;1-25(2)23(17-6-4-3-5-7-17)12-10-22(11-13-23)15-26(21(27)24-22)18-8-9-19-20(14-18)29-16-28-19;1-28(2)21(16-6-4-3-5-7-16)12-10-20(11-13-21)15-29(19(30)27-20)18-9-8-17(14-26-18)22(23,24)25;1-25(2)22(17-8-5-4-6-9-17)13-11-21(12-14-22)16-26(20(27)24-21)19-18(28-3)10-7-15-23-19;1-27(2)20(15-7-5-4-6-8-15)11-9-19(10-12-20)14-29(18(30)25-19)17-13-16(21(22,23)24)26-28(17)3/h3-12,17H,13-16,18H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,26,30);3-9,16,25H,10-15,17H2,1-2H3,(H,26,29);4-11,16H,12-15,17H2,1-3H3,(H,25,29);2*4-12H,13-17H2,1-3H3,(H,25,29);3-11H,12-16H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,25,28);3-9,14H,10-13,15-16H2,1-2H3,(H,24,27);3-9,14H,10-13,15H2,1-2H3,(H,27,30);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-8,13H,9-12,14H2,1-3H3,(H,25,30)
InChIKeyVQEDXWXUHNXCPE-UHFFFAOYSA-N
XLogP47.11
TPSA672.61 Ų
H-Bond Donors13
H-Bond Acceptors45
Rotatable Bonds43
Heavy Atoms357
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004878.03
LogP ≤ 547.11
H-Bond Donors ≤ 513
H-Bond Acceptors ≤ 1045

Analyze 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate?
The IUPAC name of 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate (CID 161368701) is 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate.
What is the SMILES notation for 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate?
The canonical SMILES for 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate is CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cc(C(F)(F)F)nn1C)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(F)(F)F)cn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(OC(F)(F)F)cc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)NCC3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc3c(c1)OCO3)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc3ncccc13)C(=O)N2.COC(=O)c1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COC(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cc1.COC(=O)c1cccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)c1.COC(=O)c1ccccc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.COc1cc(C)c(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.COc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.
What is the InChIKey of 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate?
The InChIKey is VQEDXWXUHNXCPE-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H28N4O.C24H30N4O3.C24H30N4O.3C24H29N3O3.C23H26F3N3O2.C23H30N4O2.C23H27N3O3.C22H25F3N4O.C22H28N4O2.C21H26F3N5O/c1-28(2)25(19-8-4-3-5-9-19)15-13-24(14-16-25)18-29(23(30)27-24)22-12-6-11-21-20(22)10-7-17-26-21;1-17-14-19(21(29)31-4)25-15-20(17)28-16-23(26-22(28)30)10-12-24(13-11-23,27(2)3)18-8-6-5-7-9-18;1-27(2)24(19-6-4-3-5-7-19)13-11-23(12-14-24)17-28(22(29)26-23)20-9-8-18-10-15-25-21(18)16-20;1-26(2)24(19-9-5-4-6-10-19)14-12-23(13-15-24)17-27(22(29)25-23)20-11-7-8-18(16-20)21(28)30-3;1-26(2)24(18-9-5-4-6-10-18)15-13-23(14-16-24)17-27(22(29)25-23)20-12-8-7-11-19(20)21(28)30-3;1-26(2)24(19-7-5-4-6-8-19)15-13-23(14-16-24)17-27(22(29)25-23)20-11-9-18(10-12-20)21(28)30-3;1-28(2)22(17-6-4-3-5-7-17)14-12-21(13-15-22)16-29(20(30)27-21)18-8-10-19(11-9-18)31-23(24,25)26;1-17-14-20(29-4)24-15-19(17)27-16-22(25-21(27)28)10-12-23(13-11-22,26(2)3)18-8-6-5-7-9-18;1-25(2)23(17-6-4-3-5-7-17)12-10-22(11-13-23)15-26(21(27)24-22)18-8-9-19-20(14-18)29-16-28-19;1-28(2)21(16-6-4-3-5-7-16)12-10-20(11-13-21)15-29(19(30)27-20)18-9-8-17(14-26-18)22(23,24)25;1-25(2)22(17-8-5-4-6-9-17)13-11-21(12-14-22)16-26(20(27)24-21)19-18(28-3)10-7-15-23-19;1-27(2)20(15-7-5-4-6-8-15)11-9-19(10-12-20)14-29(18(30)25-19)17-13-16(21(22,23)24)26-28(17)3/h3-12,17H,13-16,18H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,26,30);3-9,16,25H,10-15,17H2,1-2H3,(H,26,29);4-11,16H,12-15,17H2,1-3H3,(H,25,29);2*4-12H,13-17H2,1-3H3,(H,25,29);3-11H,12-16H2,1-2H3,(H,27,30);5-9,14-15H,10-13,16H2,1-4H3,(H,25,28);3-9,14H,10-13,15-16H2,1-2H3,(H,24,27);3-9,14H,10-13,15H2,1-2H3,(H,27,30);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-8,13H,9-12,14H2,1-3H3,(H,25,30).
What are the key properties of 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate?
3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate has a molecular weight of 4878.03 g/mol, XLogP of 47.11, 43 rotatable bonds, 13 hydrogen bond donors, and 45 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(1,3-benzodioxol-5-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;3-(2,3-dihydro-1H-indol-6-yl)-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-quinolin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;methyl 2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 3-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzoate;methyl 5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carboxylate is sourced from PubChem (CID 161368701), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).