N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide

C101H90Cl2N26O12 — CID 161369502

IUPACN-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide
SMILESCOc1cc(NC(=O)c2cnccn2)c2ncccc2c1.COc1cc(NC(=O)c2ncccn2)c2ncccc2c1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)cn1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)nc1.Cc1cnc(C(=O)Nc2cc(OCCN3CCOCC3)cc3cccnc23)cn1.O=C(Nc1cc(OCCN2CCOCC2)cc2cccnc12)c1cnccn1
InChIInChI=1S/C21H23N5O3.C20H21N5O3.2C15H11ClN4O.2C15H12N4O2/c1-15-13-24-19(14-23-15)21(27)25-18-12-17(11-16-3-2-4-22-20(16)18)29-10-7-26-5-8-28-9-6-26;26-20(18-14-21-4-5-22-18)24-17-13-16(12-15-2-1-3-23-19(15)17)28-11-8-25-6-9-27-10-7-25;1-9-7-19-13(8-18-9)15(21)20-12-6-11(16)5-10-3-2-4-17-14(10)12;1-9-7-18-14(19-8-9)15(21)20-12-6-11(16)5-10-3-2-4-17-13(10)12;1-21-11-8-10-4-2-5-16-13(10)12(9-11)19-15(20)14-17-6-3-7-18-14;1-21-11-7-10-3-2-4-18-14(10)12(8-11)19-15(20)13-9-16-5-6-17-13/h2-4,11-14H,5-10H2,1H3,(H,25,27);1-5,12-14H,6-11H2,(H,24,26);2*2-8H,1H3,(H,20,21);2*2-9H,1H3,(H,19,20)
InChIKeyVQGVQBBLHVZZGX-UHFFFAOYSA-N
MW1930.91 g/mol
LogP15.33
Rot. Bonds22

About N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide

N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide (PubChem CID 161369502) has the molecular formula C101H90Cl2N26O12 and a molecular weight of 1930.91 g/mol. Its IUPAC name is N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide.

Molecular Properties

Compound NameN-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide
PubChem CID161369502
Molecular FormulaC101H90Cl2N26O12
Molecular Weight1930.91 g/mol
Exact Mass1928.66
IUPAC NameN-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide
SMILESCOc1cc(NC(=O)c2cnccn2)c2ncccc2c1.COc1cc(NC(=O)c2ncccn2)c2ncccc2c1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)cn1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)nc1.Cc1cnc(C(=O)Nc2cc(OCCN3CCOCC3)cc3cccnc23)cn1.O=C(Nc1cc(OCCN2CCOCC2)cc2cccnc12)c1cnccn1
InChIInChI=1S/C21H23N5O3.C20H21N5O3.2C15H11ClN4O.2C15H12N4O2/c1-15-13-24-19(14-23-15)21(27)25-18-12-17(11-16-3-2-4-22-20(16)18)29-10-7-26-5-8-28-9-6-26;26-20(18-14-21-4-5-22-18)24-17-13-16(12-15-2-1-3-23-19(15)17)28-11-8-25-6-9-27-10-7-25;1-9-7-19-13(8-18-9)15(21)20-12-6-11(16)5-10-3-2-4-17-14(10)12;1-9-7-18-14(19-8-9)15(21)20-12-6-11(16)5-10-3-2-4-17-13(10)12;1-21-11-8-10-4-2-5-16-13(10)12(9-11)19-15(20)14-17-6-3-7-18-14;1-21-11-7-10-3-2-4-18-14(10)12(8-11)19-15(20)13-9-16-5-6-17-13/h2-4,11-14H,5-10H2,1H3,(H,25,27);1-5,12-14H,6-11H2,(H,24,26);2*2-8H,1H3,(H,20,21);2*2-9H,1H3,(H,19,20)
InChIKeyVQGVQBBLHVZZGX-UHFFFAOYSA-N
XLogP15.33
TPSA468.48 Ų
H-Bond Donors6
H-Bond Acceptors32
Rotatable Bonds22
Heavy Atoms141
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001930.91
LogP ≤ 515.33
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1032

Analyze N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide with MolForge

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Related Compounds

1-(4-Chloro-3-fluorophenyl)-3-[4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 89714170
1-(3-Chlorophenyl)-3-[3-fluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[2-fluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea;1-[3-fluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 89719222
1-(4-Chloro-3-fluorophenyl)-3-[3,5-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[3,5-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-(3-fluorophenyl)urea;1-[3,5-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 89719313
1-(4-Chloro-3-fluorophenyl)-3-[2-fluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-(4-chloro-3-fluorophenyl)-3-[3-fluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3,5-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea
CID 89719415
1-(4-Chloro-3-fluorophenyl)-3-[2,3-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-(3-chlorophenyl)-3-[2,3-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[2,3-difluoro-4-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-[3-(trifluoromethyl)phenyl]urea
CID 89719517
N-[2-[[2-[4-[[4-[3-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypropyl]morpholin-4-ium-4-yl]methyl]anilino]-2-oxoethyl]amino]-2-oxoethyl]-3-[[3-[[2-[[2-[4-[[4-[3-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypropyl]morpholin-4-ium-4-yl]methyl]anilino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-oxopropyl]-methylamino]propanamide
CID 168096990
1-(3-Chlorophenyl)-3-[3,4-difluoro-5-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-(4-chlorophenyl)-3-[3,4-difluoro-5-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]urea;1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[3,4-difluoro-5-(3-piperazin-1-ylquinoxalin-6-yl)oxyphenyl]urea;1-[3,4-difluoro-5-(3-morpholin-4-ylquinoxalin-6-yl)oxyphenyl]-3-(3-fluorophenyl)urea
CID 173514979
2-[6-[3-[6-[4-[[9-methyl-2-[3-(9-methyl-1,10-phenanthrolin-2-yl)propyl]-1,10-phenanthrolin-5-yl]oxy]pyrimidin-2-yl]-2-pyridinyl]propyl]-2-pyridinyl]-1H-pyrimidin-6-one
CID 123828212
N-[6-(2-aminoethoxy)quinolin-8-yl]pyrimidine-2-carboxamide;N-[6-(2-piperidin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide
CID 145192221
5-methyl-N-[6-[2-[1-[6-(2-piperidin-4-ylethoxy)-8-(pyrimidine-2-carbonylamino)quinolin-2-yl]piperidin-4-yl]ethoxy]quinolin-8-yl]pyrazine-2-carboxamide
CID 146221300
N-[6-(2-aminoethoxy)quinolin-8-yl]-5-methylpyrazine-2-carboxamide;N-[6-(2-aminoethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-[2-(dimethylamino)ethoxy]quinolin-8-yl]-5-methylpyrazine-2-carboxamide;N-[6-[2-(dimethylamino)ethoxy]quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-fluoroethoxy)quinolin-8-yl]pyrazine-2-carboxamide
CID 157735029
N-methyl-2-[[4-(6-morpholin-4-ylquinolin-8-yl)oxycyclohexyl]amino]pyrimidine-4-carboxamide;N-methyl-6-[[4-(6-morpholin-4-ylquinolin-8-yl)oxycyclohexyl]amino]pyrimidine-4-carboxamide;6-methyl-N-[4-(6-morpholin-4-ylquinolin-8-yl)oxycyclohexyl]pyrazin-2-amine;2-(4-methylpiperazin-1-yl)-N-[4-(6-morpholin-4-ylquinolin-8-yl)oxycyclohexyl]pyrimidin-4-amine
CID 157769615

Frequently Asked Questions

What is the IUPAC name of N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide?
The IUPAC name of N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide (CID 161369502) is N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide.
What is the SMILES notation for N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide?
The canonical SMILES for N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide is COc1cc(NC(=O)c2cnccn2)c2ncccc2c1.COc1cc(NC(=O)c2ncccn2)c2ncccc2c1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)cn1.Cc1cnc(C(=O)Nc2cc(Cl)cc3cccnc23)nc1.Cc1cnc(C(=O)Nc2cc(OCCN3CCOCC3)cc3cccnc23)cn1.O=C(Nc1cc(OCCN2CCOCC2)cc2cccnc12)c1cnccn1.
What is the InChIKey of N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide?
The InChIKey is VQGVQBBLHVZZGX-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H23N5O3.C20H21N5O3.2C15H11ClN4O.2C15H12N4O2/c1-15-13-24-19(14-23-15)21(27)25-18-12-17(11-16-3-2-4-22-20(16)18)29-10-7-26-5-8-28-9-6-26;26-20(18-14-21-4-5-22-18)24-17-13-16(12-15-2-1-3-23-19(15)17)28-11-8-25-6-9-27-10-7-25;1-9-7-19-13(8-18-9)15(21)20-12-6-11(16)5-10-3-2-4-17-14(10)12;1-9-7-18-14(19-8-9)15(21)20-12-6-11(16)5-10-3-2-4-17-13(10)12;1-21-11-8-10-4-2-5-16-13(10)12(9-11)19-15(20)14-17-6-3-7-18-14;1-21-11-7-10-3-2-4-18-14(10)12(8-11)19-15(20)13-9-16-5-6-17-13/h2-4,11-14H,5-10H2,1H3,(H,25,27);1-5,12-14H,6-11H2,(H,24,26);2*2-8H,1H3,(H,20,21);2*2-9H,1H3,(H,19,20).
What are the key properties of N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide?
N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide has a molecular weight of 1930.91 g/mol, XLogP of 15.33, 22 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for N-(6-chloroquinolin-8-yl)-5-methylpyrazine-2-carboxamide;N-(6-chloroquinolin-8-yl)-5-methylpyrimidine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrazine-2-carboxamide;N-(6-methoxyquinolin-8-yl)pyrimidine-2-carboxamide;5-methyl-N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide;N-[6-(2-morpholin-4-ylethoxy)quinolin-8-yl]pyrazine-2-carboxamide is sourced from PubChem (CID 161369502), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).