5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide

C158H194N30O10 — CID 161385611

IUPAC5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide
SMILESCCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC(=O)N(C)C.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.COCCN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2cnc(C#N)cc2C)CC12CCC(c1ccccc1)(N(C)C)CC2
InChIInChI=1S/C28H33N7O.C28H34N4O2.C26H29N7O.C26H33N5O2.C25H32N4O2.C25H33N3O2/c1-3-33(2)28(22-8-5-4-6-9-22)14-12-27(13-15-28)21-34(23-17-31-24(16-29)32-18-23)25(36)35(27)20-26(19-30)10-7-11-26;1-30(2)28(23-7-4-3-5-8-23)17-15-26(16-18-28)20-31(24-11-9-22(19-29)10-12-24)25(33)32(26)21-27(34)13-6-14-27;1-29-26(20-6-3-2-4-7-20)12-10-25(11-13-26)19-32(21-15-30-22(14-27)31-16-21)23(34)33(25)18-24(17-28)8-5-9-24;1-20-16-22(17-27)28-18-23(20)30-19-25(31(24(30)32)14-15-33-4)10-12-26(13-11-25,29(2)3)21-8-6-5-7-9-21;1-26-25(20-10-6-4-7-11-20)16-14-24(15-17-25)19-28(21-12-8-5-9-13-21)23(31)29(24)18-22(30)27(2)3;1-26(2)25(21-10-6-4-7-11-21)16-14-24(15-17-25)20-27(22-12-8-5-9-13-22)23(29)28(24)18-19-30-3/h4-6,8-9,17-18H,3,7,10-15,20-21H2,1-2H3;3-5,7-12,34H,6,13-18,20-21H2,1-2H3;2-4,6-7,15-16,29H,5,8-13,18-19H2,1H3;5-9,16,18H,10-15,19H2,1-4H3;4-13,26H,14-19H2,1-3H3;4-13H,14-20H2,1-3H3
InChIKeyVSHMKYMAQZIMCF-UHFFFAOYSA-N
MW2673.49 g/mol
LogP24.35
Rot. Bonds33

About 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide

5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide (PubChem CID 161385611) has the molecular formula C158H194N30O10 and a molecular weight of 2673.49 g/mol. Its IUPAC name is 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide.

Molecular Properties

Compound Name5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide
PubChem CID161385611
Molecular FormulaC158H194N30O10
Molecular Weight2673.49 g/mol
Exact Mass2671.56
IUPAC Name5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide
SMILESCCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC(=O)N(C)C.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.COCCN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2cnc(C#N)cc2C)CC12CCC(c1ccccc1)(N(C)C)CC2
InChIInChI=1S/C28H33N7O.C28H34N4O2.C26H29N7O.C26H33N5O2.C25H32N4O2.C25H33N3O2/c1-3-33(2)28(22-8-5-4-6-9-22)14-12-27(13-15-28)21-34(23-17-31-24(16-29)32-18-23)25(36)35(27)20-26(19-30)10-7-11-26;1-30(2)28(23-7-4-3-5-8-23)17-15-26(16-18-28)20-31(24-11-9-22(19-29)10-12-24)25(33)32(26)21-27(34)13-6-14-27;1-29-26(20-6-3-2-4-7-20)12-10-25(11-13-26)19-32(21-15-30-22(14-27)31-16-21)23(34)33(25)18-24(17-28)8-5-9-24;1-20-16-22(17-27)28-18-23(20)30-19-25(31(24(30)32)14-15-33-4)10-12-26(13-11-25,29(2)3)21-8-6-5-7-9-21;1-26-25(20-10-6-4-7-11-20)16-14-24(15-17-25)19-28(21-12-8-5-9-13-21)23(31)29(24)18-22(30)27(2)3;1-26(2)25(21-10-6-4-7-11-21)16-14-24(15-17-25)20-27(22-12-8-5-9-13-22)23(29)28(24)18-19-30-3/h4-6,8-9,17-18H,3,7,10-15,20-21H2,1-2H3;3-5,7-12,34H,6,13-18,20-21H2,1-2H3;2-4,6-7,15-16,29H,5,8-13,18-19H2,1H3;5-9,16,18H,10-15,19H2,1-4H3;4-13,26H,14-19H2,1-3H3;4-13H,14-20H2,1-3H3
InChIKeyVSHMKYMAQZIMCF-UHFFFAOYSA-N
XLogP24.35
TPSA444.51 Ų
H-Bond Donors3
H-Bond Acceptors27
Rotatable Bonds33
Heavy Atoms198
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002673.49
LogP ≤ 524.35
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1027

Analyze 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide with MolForge

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Related Compounds

CID 157289609
CID 157289609
1-(Cyclopropylmethyl)-8-(methylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-fluorophenyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(4-fluorophenyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;4-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-8-phenyl-3-(2-phenylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(ethylamino)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(methylamino)-1-(oxetan-3-ylmethyl)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 157481599
4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
CID 157523056
8-Benzyl-8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[2-(piperazine-1-carbonyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyrimidin-5-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyrrolidin-1-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one
CID 157592768
1-(Cyclobutylmethyl)-8-(dimethylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(methylamino)-3-[4-methyl-6-(trifluoromethyl)-3-pyridinyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-3-[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-8-phenyl-3-(2-piperazin-1-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;dihydrochloride
CID 158062250
3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;5-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-[(1-hydroxycyclobutyl)methyl]pyridine-2-carboxamide
CID 158396236
8-(Dimethylamino)-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-2-carbonitrile;8-(dimethylamino)-8-phenyl-3-[6-(trifluoromethyl)-3-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
CID 158793673
5-(Cyclopropylmethyl)-2-(dimethylamino)-2-(3-fluorophenyl)-7-[(1-hydroxycyclobutyl)methyl]-5,7-diazaspiro[3.4]octan-6-one;5-[5-(cyclopropylmethyl)-2-(dimethylamino)-6-oxo-2-phenyl-5,7-diazaspiro[3.4]octan-7-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile;5-(cyclopropylmethyl)-2-(dimethylamino)-2-phenyl-7-(2-pyridin-4-ylpyrimidin-5-yl)-5,7-diazaspiro[3.4]octan-6-one;2-(dimethylamino)-2-(3-fluorophenyl)-7-[(4-morpholin-4-ylphenyl)methyl]-5,7-diazaspiro[3.4]octan-6-one
CID 159340891
8-Amino-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-fluorophenyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-3-pyrimidin-5-yl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-methylpyrimidin-5-yl)-8-phenyl-1-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;8-(dimethylamino)-8-phenyl-3-pyrimidin-5-yl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-8-phenyl-3-pyrimidin-5-yl-1,3-diazaspiro[4.5]decan-2-one
CID 159417439
8-(dimethylamino)-3-[2-morpholin-4-yl-4-(trifluoromethyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(2-hydroxyethyl)pyrimidine-2-carboxamide;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;4-[5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidin-2-yl]benzonitrile
CID 159428656
8-(Dimethylamino)-3-[2-(1,1-dioxo-1,4-thiazinan-4-yl)-4-methylpyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile;8-(dimethylamino)-3-[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-2-carbonitrile;8-(dimethylamino)-8-phenyl-3-[6-(trifluoromethyl)-3-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;2-[1-(3-methoxypropyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile
CID 160011477
8-(dimethylamino)-3-[2-morpholin-4-yl-4-(trifluoromethyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(2-hydroxyethyl)pyrimidine-2-carboxamide;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;8-(dimethylamino)-8-phenyl-3-(2-pyridin-3-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyridin-4-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one
CID 160345454

Frequently Asked Questions

What is the IUPAC name of 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide?
The IUPAC name of 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide (CID 161385611) is 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide.
What is the SMILES notation for 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide?
The canonical SMILES for 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide is CCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C#N)cc1)C(=O)N2CC1(O)CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1ccccc1)C(=O)N2CC(=O)N(C)C.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1(C#N)CCC1.COCCN1C(=O)N(c2ccccc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCCN1C(=O)N(c2cnc(C#N)cc2C)CC12CCC(c1ccccc1)(N(C)C)CC2.
What is the InChIKey of 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide?
The InChIKey is VSHMKYMAQZIMCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H33N7O.C28H34N4O2.C26H29N7O.C26H33N5O2.C25H32N4O2.C25H33N3O2/c1-3-33(2)28(22-8-5-4-6-9-22)14-12-27(13-15-28)21-34(23-17-31-24(16-29)32-18-23)25(36)35(27)20-26(19-30)10-7-11-26;1-30(2)28(23-7-4-3-5-8-23)17-15-26(16-18-28)20-31(24-11-9-22(19-29)10-12-24)25(33)32(26)21-27(34)13-6-14-27;1-29-26(20-6-3-2-4-7-20)12-10-25(11-13-26)19-32(21-15-30-22(14-27)31-16-21)23(34)33(25)18-24(17-28)8-5-9-24;1-20-16-22(17-27)28-18-23(20)30-19-25(31(24(30)32)14-15-33-4)10-12-26(13-11-25,29(2)3)21-8-6-5-7-9-21;1-26-25(20-10-6-4-7-11-20)16-14-24(15-17-25)19-28(21-12-8-5-9-13-21)23(31)29(24)18-22(30)27(2)3;1-26(2)25(21-10-6-4-7-11-21)16-14-24(15-17-25)20-27(22-12-8-5-9-13-22)23(29)28(24)18-19-30-3/h4-6,8-9,17-18H,3,7,10-15,20-21H2,1-2H3;3-5,7-12,34H,6,13-18,20-21H2,1-2H3;2-4,6-7,15-16,29H,5,8-13,18-19H2,1H3;5-9,16,18H,10-15,19H2,1-4H3;4-13,26H,14-19H2,1-3H3;4-13H,14-20H2,1-3H3.
What are the key properties of 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide?
5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide has a molecular weight of 2673.49 g/mol, XLogP of 24.35, 33 rotatable bonds, 3 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[1-[(1-cyanocyclobutyl)methyl]-8-[ethyl(methyl)amino]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[1-[(1-cyanocyclobutyl)methyl]-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;4-[8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzonitrile;8-(dimethylamino)-1-(2-methoxyethyl)-3,8-diphenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-methoxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;N,N-dimethyl-2-[8-(methylamino)-2-oxo-3,8-diphenyl-1,3-diazaspiro[4.5]decan-1-yl]acetamide is sourced from PubChem (CID 161385611), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).