N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide

C262H220ClF19N40O25S2 — CID 161387373

IUPACN-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
SMILESC/C=C/c1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.C=Cc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.CCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cn3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(F)c(F)c3F)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ncc(C)s3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3nnc(C4CC4)s3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/C3CC3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(CCc3ccc(F)cc3)cc2n(C)c1=O.Cc1ccnc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)c1
InChIInChI=1S/C32H25F4N3O2.C29H24F3N3O2.C27H24F3N3O2.C27H22F3N3O2.C26H20F3N3O2.C25H19F3N4O3.C25H23N5O3.C24H20ClN5O3.C24H22N6O3S.C23H21N5O3S/c1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-6-10-23(34-27(36)19-4-3-5-21(12-19)29(30,31)32)14-24(17)25-13-20-16-33-22(11-9-18-7-8-18)15-26(20)35(2)28(25)37;2*1-4-6-20-14-24-18(15-31-20)12-23(26(35)33(24)3)22-13-21(10-9-16(22)2)32-25(34)17-7-5-8-19(11-17)27(28,29)30;1-4-19-13-23-17(14-30-19)11-22(25(34)32(23)3)21-12-20(9-8-15(21)2)31-24(33)16-6-5-7-18(10-16)26(27,28)29;1-12-4-5-14(23(33)31-25(35)30-19-7-6-18(26)21(27)22(19)28)9-16(12)17-10-15-11-29-13(2)8-20(15)32(3)24(17)34;1-14-7-8-26-22(9-14)28-25(33)29-23(31)17-6-5-15(2)19(11-17)20-12-18-13-27-16(3)10-21(18)30(4)24(20)32;1-13-4-5-15(22(31)29-24(33)28-21-7-6-17(25)12-27-21)9-18(13)19-10-16-11-26-14(2)8-20(16)30(3)23(19)32;1-12-4-5-15(20(31)26-23(33)27-24-29-28-21(34-24)14-6-7-14)9-17(12)18-10-16-11-25-13(2)8-19(16)30(3)22(18)32;1-12-5-6-15(20(29)26-22(31)27-23-25-10-14(3)32-23)8-17(12)18-9-16-11-24-13(2)7-19(16)28(4)21(18)30/h3-8,10-12,14-18H,9,13H2,1-2H3,(H,38,40);3-6,9-16,18H,7-8H2,1-2H3,(H,34,36);5,7-15H,4,6H2,1-3H3,(H,32,34);4-15H,1-3H3,(H,32,34);4-14H,1H2,2-3H3,(H,31,33);4-11H,1-3H3,(H2,30,31,33,35);5-13H,1-4H3,(H2,26,28,29,31,33);4-12H,1-3H3,(H2,27,28,29,31,33);4-5,8-11,14H,6-7H2,1-3H3,(H2,26,27,29,31,33);5-11H,1-4H3,(H2,25,26,27,29,31)/b;11-9+;;6-4+;;;;;;
InChIKeyVSNIYQUQYHCEMU-RQAZUSSISA-N
MW4789.45 g/mol
LogP52.44
Rot. Bonds40

About N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide

N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide (PubChem CID 161387373) has the molecular formula C262H220ClF19N40O25S2 and a molecular weight of 4789.45 g/mol. Its IUPAC name is N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound NameN-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
PubChem CID161387373
Molecular FormulaC262H220ClF19N40O25S2
Molecular Weight4789.45 g/mol
Exact Mass4785.60
IUPAC NameN-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
SMILESC/C=C/c1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.C=Cc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.CCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cn3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(F)c(F)c3F)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ncc(C)s3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3nnc(C4CC4)s3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/C3CC3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(CCc3ccc(F)cc3)cc2n(C)c1=O.Cc1ccnc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)c1
InChIInChI=1S/C32H25F4N3O2.C29H24F3N3O2.C27H24F3N3O2.C27H22F3N3O2.C26H20F3N3O2.C25H19F3N4O3.C25H23N5O3.C24H20ClN5O3.C24H22N6O3S.C23H21N5O3S/c1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-6-10-23(34-27(36)19-4-3-5-21(12-19)29(30,31)32)14-24(17)25-13-20-16-33-22(11-9-18-7-8-18)15-26(20)35(2)28(25)37;2*1-4-6-20-14-24-18(15-31-20)12-23(26(35)33(24)3)22-13-21(10-9-16(22)2)32-25(34)17-7-5-8-19(11-17)27(28,29)30;1-4-19-13-23-17(14-30-19)11-22(25(34)32(23)3)21-12-20(9-8-15(21)2)31-24(33)16-6-5-7-18(10-16)26(27,28)29;1-12-4-5-14(23(33)31-25(35)30-19-7-6-18(26)21(27)22(19)28)9-16(12)17-10-15-11-29-13(2)8-20(15)32(3)24(17)34;1-14-7-8-26-22(9-14)28-25(33)29-23(31)17-6-5-15(2)19(11-17)20-12-18-13-27-16(3)10-21(18)30(4)24(20)32;1-13-4-5-15(22(31)29-24(33)28-21-7-6-17(25)12-27-21)9-18(13)19-10-16-11-26-14(2)8-20(16)30(3)23(19)32;1-12-4-5-15(20(31)26-23(33)27-24-29-28-21(34-24)14-6-7-14)9-17(12)18-10-16-11-25-13(2)8-19(16)30(3)22(18)32;1-12-5-6-15(20(29)26-22(31)27-23-25-10-14(3)32-23)8-17(12)18-9-16-11-24-13(2)7-19(16)28(4)21(18)30/h3-8,10-12,14-18H,9,13H2,1-2H3,(H,38,40);3-6,9-16,18H,7-8H2,1-2H3,(H,34,36);5,7-15H,4,6H2,1-3H3,(H,32,34);4-15H,1-3H3,(H,32,34);4-14H,1H2,2-3H3,(H,31,33);4-11H,1-3H3,(H2,30,31,33,35);5-13H,1-4H3,(H2,26,28,29,31,33);4-12H,1-3H3,(H2,27,28,29,31,33);4-5,8-11,14H,6-7H2,1-3H3,(H2,26,27,29,31,33);5-11H,1-4H3,(H2,25,26,27,29,31)/b;11-9+;;6-4+;;;;;;
InChIKeyVSNIYQUQYHCEMU-RQAZUSSISA-N
XLogP52.44
TPSA849.85 Ų
H-Bond Donors15
H-Bond Acceptors52
Rotatable Bonds40
Heavy Atoms349
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004789.45
LogP ≤ 552.44
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1052

Analyze N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide with MolForge

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What is the IUPAC name of N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide?
The IUPAC name of N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide (CID 161387373) is N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide is C/C=C/c1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.C=Cc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.CCCc1cc2c(cn1)cc(-c1cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(Cl)cn3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ccc(F)c(F)c3F)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3ncc(C)s3)ccc1C)c(=O)n2C.Cc1cc2c(cn1)cc(-c1cc(C(=O)NC(=O)Nc3nnc(C4CC4)s3)ccc1C)c(=O)n2C.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(/C=C/C3CC3)cc2n(C)c1=O.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc2cnc(CCc3ccc(F)cc3)cc2n(C)c1=O.Cc1ccnc(NC(=O)NC(=O)c2ccc(C)c(-c3cc4cnc(C)cc4n(C)c3=O)c2)c1.
What is the InChIKey of N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide?
The InChIKey is VSNIYQUQYHCEMU-RQAZUSSISA-N. The full InChI is InChI=1S/C32H25F4N3O2.C29H24F3N3O2.C27H24F3N3O2.C27H22F3N3O2.C26H20F3N3O2.C25H19F3N4O3.C25H23N5O3.C24H20ClN5O3.C24H22N6O3S.C23H21N5O3S/c1-19-6-12-26(38-30(40)21-4-3-5-23(14-21)32(34,35)36)16-27(19)28-15-22-18-37-25(17-29(22)39(2)31(28)41)13-9-20-7-10-24(33)11-8-20;1-17-6-10-23(34-27(36)19-4-3-5-21(12-19)29(30,31)32)14-24(17)25-13-20-16-33-22(11-9-18-7-8-18)15-26(20)35(2)28(25)37;2*1-4-6-20-14-24-18(15-31-20)12-23(26(35)33(24)3)22-13-21(10-9-16(22)2)32-25(34)17-7-5-8-19(11-17)27(28,29)30;1-4-19-13-23-17(14-30-19)11-22(25(34)32(23)3)21-12-20(9-8-15(21)2)31-24(33)16-6-5-7-18(10-16)26(27,28)29;1-12-4-5-14(23(33)31-25(35)30-19-7-6-18(26)21(27)22(19)28)9-16(12)17-10-15-11-29-13(2)8-20(15)32(3)24(17)34;1-14-7-8-26-22(9-14)28-25(33)29-23(31)17-6-5-15(2)19(11-17)20-12-18-13-27-16(3)10-21(18)30(4)24(20)32;1-13-4-5-15(22(31)29-24(33)28-21-7-6-17(25)12-27-21)9-18(13)19-10-16-11-26-14(2)8-20(16)30(3)23(19)32;1-12-4-5-15(20(31)26-23(33)27-24-29-28-21(34-24)14-6-7-14)9-17(12)18-10-16-11-25-13(2)8-19(16)30(3)22(18)32;1-12-5-6-15(20(29)26-22(31)27-23-25-10-14(3)32-23)8-17(12)18-9-16-11-24-13(2)7-19(16)28(4)21(18)30/h3-8,10-12,14-18H,9,13H2,1-2H3,(H,38,40);3-6,9-16,18H,7-8H2,1-2H3,(H,34,36);5,7-15H,4,6H2,1-3H3,(H,32,34);4-15H,1-3H3,(H,32,34);4-14H,1H2,2-3H3,(H,31,33);4-11H,1-3H3,(H2,30,31,33,35);5-13H,1-4H3,(H2,26,28,29,31,33);4-12H,1-3H3,(H2,27,28,29,31,33);4-5,8-11,14H,6-7H2,1-3H3,(H2,26,27,29,31,33);5-11H,1-4H3,(H2,25,26,27,29,31)/b;11-9+;;6-4+;;;;;;.
What are the key properties of N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide?
N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide has a molecular weight of 4789.45 g/mol, XLogP of 52.44, 40 rotatable bonds, 15 hydrogen bond donors, and 52 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(5-chloro-2-pyridinyl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;N-[3-[7-[(E)-2-cyclopropylethenyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[(5-cyclopropyl-1,3,4-thiadiazol-2-yl)carbamoyl]-3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylbenzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(4-methyl-2-pyridinyl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]benzamide;3-(1,7-dimethyl-2-oxo-1,6-naphthyridin-3-yl)-4-methyl-N-[(2,3,4-trifluorophenyl)carbamoyl]benzamide;N-[3-(7-ethenyl-1-methyl-2-oxo-1,6-naphthyridin-3-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-[2-(4-fluorophenyl)ethyl]-1-methyl-2-oxo-1,6-naphthyridin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[1-methyl-2-oxo-7-[(E)-prop-1-enyl]-1,6-naphthyridin-3-yl]phenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-2-oxo-7-propyl-1,6-naphthyridin-3-yl)phenyl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 161387373), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).