N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide

C274H366N54O24S3 — CID 161404394

IUPACN-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCC(N)=O)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(C(N)=O)cn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1nccc(C#N)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncccc1C#N)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccn(C)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccon1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nccs1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nncs1)C(=O)N2CC1CCC1.CSc1n[nH]c(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1C#N.Cc1cc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)no1
InChIInChI=1S/C30H39N5O3.C30H37N5O2.C29H36N6O2.C28H37N7O2S.C27H38N6O2.C27H37N5O3.C26H35N5O3.C26H35N5O2S.C26H38N4O3.C25H34N6O2S/c1-33(2)30(24-9-4-3-5-10-24)15-13-29(14-16-30)21-34(28(38)35(29)19-22-7-6-8-22)20-26(36)17-25-12-11-23(18-32-25)27(31)37;1-33(2)30(25-11-4-3-5-12-25)15-13-29(14-16-30)22-34(28(37)35(29)20-23-8-6-9-23)21-26(36)18-27-24(19-31)10-7-17-32-27;1-33(2)29(23-9-4-3-5-10-23)14-12-28(13-15-29)21-34(27(37)35(28)19-22-7-6-8-22)20-25(36)17-26-31-16-11-24(18-30)32-26;1-33(2)28(21-10-5-4-6-11-21)14-12-27(13-15-28)19-34(26(37)35(27)17-20-8-7-9-20)18-23(36)30-24-22(16-29)25(38-3)32-31-24;1-30(2)27(22-10-5-4-6-11-22)15-13-26(14-16-27)20-32(25(35)33(26)18-21-8-7-9-21)19-24(34)28-23-12-17-31(3)29-23;1-20-16-23(29-35-20)28-24(33)18-31-19-26(32(25(31)34)17-21-8-7-9-21)12-14-27(15-13-26,30(2)3)22-10-5-4-6-11-22;1-29(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-30(18-23(32)27-22-11-16-34-28-22)24(33)31(25)17-20-7-6-8-20;1-29(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)19-30(18-22(32)28-23-27-15-16-34-23)24(33)31(25)17-20-7-6-8-20;1-28(2)26(21-9-4-3-5-10-21)15-13-25(14-16-26)19-29(18-22(31)11-12-23(27)32)24(33)30(25)17-20-7-6-8-20;1-29(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)17-30(16-21(32)27-22-28-26-18-34-22)23(33)31(24)15-19-7-6-8-19/h3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3,(H2,31,37);3-5,7,10-12,17,23H,6,8-9,13-16,18,20-22H2,1-2H3;3-5,9-11,16,22H,6-8,12-15,17,19-21H2,1-2H3;4-6,10-11,20H,7-9,12-15,17-19H2,1-3H3,(H2,30,31,32,36);4-6,10-12,17,21H,7-9,13-16,18-20H2,1-3H3,(H,28,29,34);4-6,10-11,16,21H,7-9,12-15,17-19H2,1-3H3,(H,28,29,33);3-5,9-11,16,20H,6-8,12-15,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,15-16,20H,6-8,11-14,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,20H,6-8,11-19H2,1-2H3,(H2,27,32);3-5,9-10,18-19H,6-8,11-17H2,1-2H3,(H,27,28,32)
InChIKeyVUQLJBAFGCAZAM-UHFFFAOYSA-N
MW4896.50 g/mol
LogP39.11
Rot. Bonds77

About N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide

N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide (PubChem CID 161404394) has the molecular formula C274H366N54O24S3 and a molecular weight of 4896.50 g/mol. Its IUPAC name is N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide.

Molecular Properties

Compound NameN-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide
PubChem CID161404394
Molecular FormulaC274H366N54O24S3
Molecular Weight4896.50 g/mol
Exact Mass4892.82
IUPAC NameN-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCC(N)=O)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(C(N)=O)cn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1nccc(C#N)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncccc1C#N)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccn(C)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccon1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nccs1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nncs1)C(=O)N2CC1CCC1.CSc1n[nH]c(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1C#N.Cc1cc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)no1
InChIInChI=1S/C30H39N5O3.C30H37N5O2.C29H36N6O2.C28H37N7O2S.C27H38N6O2.C27H37N5O3.C26H35N5O3.C26H35N5O2S.C26H38N4O3.C25H34N6O2S/c1-33(2)30(24-9-4-3-5-10-24)15-13-29(14-16-30)21-34(28(38)35(29)19-22-7-6-8-22)20-26(36)17-25-12-11-23(18-32-25)27(31)37;1-33(2)30(25-11-4-3-5-12-25)15-13-29(14-16-30)22-34(28(37)35(29)20-23-8-6-9-23)21-26(36)18-27-24(19-31)10-7-17-32-27;1-33(2)29(23-9-4-3-5-10-23)14-12-28(13-15-29)21-34(27(37)35(28)19-22-7-6-8-22)20-25(36)17-26-31-16-11-24(18-30)32-26;1-33(2)28(21-10-5-4-6-11-21)14-12-27(13-15-28)19-34(26(37)35(27)17-20-8-7-9-20)18-23(36)30-24-22(16-29)25(38-3)32-31-24;1-30(2)27(22-10-5-4-6-11-22)15-13-26(14-16-27)20-32(25(35)33(26)18-21-8-7-9-21)19-24(34)28-23-12-17-31(3)29-23;1-20-16-23(29-35-20)28-24(33)18-31-19-26(32(25(31)34)17-21-8-7-9-21)12-14-27(15-13-26,30(2)3)22-10-5-4-6-11-22;1-29(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-30(18-23(32)27-22-11-16-34-28-22)24(33)31(25)17-20-7-6-8-20;1-29(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)19-30(18-22(32)28-23-27-15-16-34-23)24(33)31(25)17-20-7-6-8-20;1-28(2)26(21-9-4-3-5-10-21)15-13-25(14-16-26)19-29(18-22(31)11-12-23(27)32)24(33)30(25)17-20-7-6-8-20;1-29(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)17-30(16-21(32)27-22-28-26-18-34-22)23(33)31(24)15-19-7-6-8-19/h3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3,(H2,31,37);3-5,7,10-12,17,23H,6,8-9,13-16,18,20-22H2,1-2H3;3-5,9-11,16,22H,6-8,12-15,17,19-21H2,1-2H3;4-6,10-11,20H,7-9,12-15,17-19H2,1-3H3,(H2,30,31,32,36);4-6,10-12,17,21H,7-9,13-16,18-20H2,1-3H3,(H,28,29,34);4-6,10-11,16,21H,7-9,12-15,17-19H2,1-3H3,(H,28,29,33);3-5,9-11,16,20H,6-8,12-15,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,15-16,20H,6-8,11-14,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,20H,6-8,11-19H2,1-2H3,(H2,27,32);3-5,9-10,18-19H,6-8,11-17H2,1-2H3,(H,27,28,32)
InChIKeyVUQLJBAFGCAZAM-UHFFFAOYSA-N
XLogP39.11
TPSA857.12 Ų
H-Bond Donors9
H-Bond Acceptors52
Rotatable Bonds77
Heavy Atoms355
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004896.50
LogP ≤ 539.11
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1052

Analyze N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide with MolForge

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Related Compounds

5-tert-butyl-N-methyl-1,2-oxazol-3-amine;bis(3-cyclopropyl-N,1-dimethylpyrazol-5-amine);3-(methylamino)benzonitrile;N-methyl-1,3-benzothiazol-6-amine;bis(N-methyl-3-(methylamino)benzamide);bis(N-methyl-3-[3-(methylamino)phenyl]-1,2,4-oxadiazol-5-amine);N-methyl-1,2-oxazol-3-amine;N-methyl-3-(1H-pyrazol-5-yl)aniline;N-methyl-3-pyridin-4-ylaniline;bis(N-methyl-3-(1,3-thiazol-4-yl)aniline);N-methyl-3-(3H-1,2,4-triazol-3-yl)aniline
CID 157379786
CID 157677602
CID 157677602
CID 158357924
CID 158357924
5-tert-butyl-N-methyl-1,2-oxazol-3-amine;N-cyclobutyl-3-(methylamino)benzamide;3-cyclopropyl-N,1-dimethylpyrazol-5-amine;N-(cyclopropylmethyl)-3-(methylamino)benzamide;bis(N-methyl-3-(methylamino)benzamide);bis(N-methyl-3-[3-(methylamino)phenyl]-1,2,4-oxadiazol-5-amine);N-methyl-3-(methylamino)-N-propan-2-ylbenzamide;[2-methyl-6-(methylamino)-4-pyridinyl]-pyrrolidin-1-ylmethanone;N-methyl-1,2-oxazol-3-amine;N-methyl-3-(1H-pyrazol-5-yl)aniline;bis(N-methyl-3-(1,3-thiazol-4-yl)aniline);N-methyl-3-(3H-1,2,4-triazol-3-yl)aniline;N,N,2-trimethyl-6-(methylamino)pyridine-4-carboxamide
CID 159779485
5-tert-butyl-N-methyl-1,2-oxazol-3-amine;3-cyclopropyl-N,1-dimethylpyrazol-5-amine;bis(N-methyl-3-(methylamino)benzamide);bis(N-methyl-3-[3-(methylamino)phenyl]-1,2,4-oxadiazol-5-amine);N-methyl-3-(methylamino)-N-propan-2-ylbenzamide;[2-methyl-6-(methylamino)-4-pyridinyl]-pyrrolidin-1-ylmethanone;N-methyl-1,2-oxazol-3-amine;N-methyl-3-(1H-pyrazol-5-yl)aniline;bis(N-methyl-3-(1,3-thiazol-4-yl)aniline);N-methyl-3-(3H-1,2,4-triazol-3-yl)aniline
CID 160092194
5-tert-butyl-N-methyl-1,2-oxazol-3-amine;3-cyclopropyl-N,1-dimethylpyrazol-5-amine;tris(N-methyl-3-(methylamino)benzamide);bis(N-methyl-3-[3-(methylamino)phenyl]-1,2,4-oxadiazol-5-amine);N-methyl-3-(methylamino)-N-propan-2-ylbenzamide;[2-methyl-6-(methylamino)-4-pyridinyl]-pyrrolidin-1-ylmethanone;N-methyl-1,2-oxazol-3-amine;N-methyl-3-(1H-pyrazol-5-yl)aniline;N-methyl-3-pyridin-4-ylaniline;bis(N-methyl-3-(1,3-thiazol-4-yl)aniline);N-methyl-3-(3H-1,2,4-triazol-3-yl)aniline
CID 161071656
CID 161416705
CID 161416705
CID 161678337
CID 161678337
CID 161730896
CID 161730896

Frequently Asked Questions

What is the IUPAC name of N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide?
The IUPAC name of N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide (CID 161404394) is N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide.
What is the SMILES notation for N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide?
The canonical SMILES for N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide is CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)CCC(N)=O)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ccc(C(N)=O)cn1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1nccc(C#N)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Cc1ncccc1C#N)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccn(C)n1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1ccon1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nccs1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(CC(=O)Nc1nncs1)C(=O)N2CC1CCC1.CSc1n[nH]c(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)c1C#N.Cc1cc(NC(=O)CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)no1.
What is the InChIKey of N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide?
The InChIKey is VUQLJBAFGCAZAM-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H39N5O3.C30H37N5O2.C29H36N6O2.C28H37N7O2S.C27H38N6O2.C27H37N5O3.C26H35N5O3.C26H35N5O2S.C26H38N4O3.C25H34N6O2S/c1-33(2)30(24-9-4-3-5-10-24)15-13-29(14-16-30)21-34(28(38)35(29)19-22-7-6-8-22)20-26(36)17-25-12-11-23(18-32-25)27(31)37;1-33(2)30(25-11-4-3-5-12-25)15-13-29(14-16-30)22-34(28(37)35(29)20-23-8-6-9-23)21-26(36)18-27-24(19-31)10-7-17-32-27;1-33(2)29(23-9-4-3-5-10-23)14-12-28(13-15-29)21-34(27(37)35(28)19-22-7-6-8-22)20-25(36)17-26-31-16-11-24(18-30)32-26;1-33(2)28(21-10-5-4-6-11-21)14-12-27(13-15-28)19-34(26(37)35(27)17-20-8-7-9-20)18-23(36)30-24-22(16-29)25(38-3)32-31-24;1-30(2)27(22-10-5-4-6-11-22)15-13-26(14-16-27)20-32(25(35)33(26)18-21-8-7-9-21)19-24(34)28-23-12-17-31(3)29-23;1-20-16-23(29-35-20)28-24(33)18-31-19-26(32(25(31)34)17-21-8-7-9-21)12-14-27(15-13-26,30(2)3)22-10-5-4-6-11-22;1-29(2)26(21-9-4-3-5-10-21)14-12-25(13-15-26)19-30(18-23(32)27-22-11-16-34-28-22)24(33)31(25)17-20-7-6-8-20;1-29(2)26(21-9-4-3-5-10-21)13-11-25(12-14-26)19-30(18-22(32)28-23-27-15-16-34-23)24(33)31(25)17-20-7-6-8-20;1-28(2)26(21-9-4-3-5-10-21)15-13-25(14-16-26)19-29(18-22(31)11-12-23(27)32)24(33)30(25)17-20-7-6-8-20;1-29(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)17-30(16-21(32)27-22-28-26-18-34-22)23(33)31(24)15-19-7-6-8-19/h3-5,9-12,18,22H,6-8,13-17,19-21H2,1-2H3,(H2,31,37);3-5,7,10-12,17,23H,6,8-9,13-16,18,20-22H2,1-2H3;3-5,9-11,16,22H,6-8,12-15,17,19-21H2,1-2H3;4-6,10-11,20H,7-9,12-15,17-19H2,1-3H3,(H2,30,31,32,36);4-6,10-12,17,21H,7-9,13-16,18-20H2,1-3H3,(H,28,29,34);4-6,10-11,16,21H,7-9,12-15,17-19H2,1-3H3,(H,28,29,33);3-5,9-11,16,20H,6-8,12-15,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,15-16,20H,6-8,11-14,17-19H2,1-2H3,(H,27,28,32);3-5,9-10,20H,6-8,11-19H2,1-2H3,(H2,27,32);3-5,9-10,18-19H,6-8,11-17H2,1-2H3,(H,27,28,32).
What are the key properties of N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide?
N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide has a molecular weight of 4896.50 g/mol, XLogP of 39.11, 77 rotatable bonds, 9 hydrogen bond donors, and 52 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-cyano-3-methylsulfanyl-1H-pyrazol-5-yl)-2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1-methylpyrazol-3-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,2-oxazol-3-yl)acetamide;5-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-oxopentanamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carbonitrile;6-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyridine-3-carboxamide;2-[3-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-2-oxopropyl]pyrimidine-4-carbonitrile;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide;2-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(1,3-thiazol-2-yl)acetamide is sourced from PubChem (CID 161404394), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).