3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine

C148H117ClF11N29 — CID 161405210

About 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine

3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine (PubChem CID 161405210) has the molecular formula C148H117ClF11N29 and a molecular weight of 2546.20 g/mol. Its IUPAC name is 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine.

Molecular Properties

• Compound Name: 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine
• PubChem CID: 161405210
• Molecular Formula: C148H117ClF11N29
• Molecular Weight: 2546.20 g/mol
• Exact Mass: 2543.96
• IUPAC Name: 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine
• SMILES: C=C(c1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12)C(C)(F)F.CCc1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12.CN(CC(C)(F)F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12.Cc1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12.FCc1cccc2cc(Nc3[nH]nc4ncccc34)ccc12.FCc1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.Fc1ccc(C2CC2)c2ccc(Cc3[nH]nc4cccnc34)cc12.Fc1ccc(Cl)c2ccc(Cc3[nH]nc4cccnc34)cc12
• InChI: InChI=1S/C21H16F3N3.C20H16FN3.C19H18F2N6.C19H16FN3.C18H14FN3.C17H11ClFN3.2C17H13FN4/c1-12(21(2,23)24)14-7-8-17(22)16-10-13(5-6-15(14)16)11-19-20-18(26-27-19)4-3-9-25-20;21-17-8-7-14(13-4-5-13)15-6-3-12(10-16(15)17)11-19-20-18(23-24-19)2-1-9-22-20;1-19(20,21)11-27(2)18-14-6-5-13(10-12(14)7-9-23-18)24-17-16-15(25-26-17)4-3-8-22-16;1-2-13-6-8-16(20)15-10-12(5-7-14(13)15)11-18-19-17(22-23-18)4-3-9-21-19;1-11-4-7-15(19)14-9-12(5-6-13(11)14)10-17-18-16(21-22-17)3-2-8-20-18;18-13-5-6-14(19)12-8-10(3-4-11(12)13)9-16-17-15(21-22-16)2-1-7-20-17;18-10-12-4-1-3-11-9-13(6-7-14(11)12)20-17-16-15(21-22-17)5-2-8-19-16;18-10-12-4-1-3-11-9-13(6-7-14(11)12)20-17-15-5-2-8-19-16(15)21-22-17/h3-10H,1,11H2,2H3,(H,26,27);1-3,6-10,13H,4-5,11H2,(H,23,24);3-10H,11H2,1-2H3,(H2,24,25,26);3-10H,2,11H2,1H3,(H,22,23);2-9H,10H2,1H3,(H,21,22);1-8H,9H2,(H,21,22);1-9H,10H2,(H2,20,21,22);1-9H,10H2,(H2,19,20,21,22)
• InChIKey: VUTBLTRPFARGNS-UHFFFAOYSA-N
• XLogP: 36.26
• TPSA: 384.78 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 21
• Rotatable Bonds: 25
• Heavy Atoms: 189
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2546.20
LogP ≤ 5	36.26
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	21

Frequently Asked Questions

What is the IUPAC name of 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine?

The IUPAC name of 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine (CID 161405210) is 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine.

What is the SMILES notation for 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine?

The canonical SMILES for 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine is C=C(c1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12)C(C)(F)F.CCc1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12.CN(CC(C)(F)F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12.Cc1ccc(F)c2cc(Cc3[nH]nc4cccnc34)ccc12.FCc1cccc2cc(Nc3[nH]nc4ncccc34)ccc12.FCc1cccc2cc(Nc3n[nH]c4cccnc34)ccc12.Fc1ccc(C2CC2)c2ccc(Cc3[nH]nc4cccnc34)cc12.Fc1ccc(Cl)c2ccc(Cc3[nH]nc4cccnc34)cc12.

What is the InChIKey of 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine?

The InChIKey is VUTBLTRPFARGNS-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H16F3N3.C20H16FN3.C19H18F2N6.C19H16FN3.C18H14FN3.C17H11ClFN3.2C17H13FN4/c1-12(21(2,23)24)14-7-8-17(22)16-10-13(5-6-15(14)16)11-19-20-18(26-27-19)4-3-9-25-20;21-17-8-7-14(13-4-5-13)15-6-3-12(10-16(15)17)11-19-20-18(23-24-19)2-1-9-22-20;1-19(20,21)11-27(2)18-14-6-5-13(10-12(14)7-9-23-18)24-17-16-15(25-26-17)4-3-8-22-16;1-2-13-6-8-16(20)15-10-12(5-7-14(13)15)11-18-19-17(22-23-18)4-3-9-21-19;1-11-4-7-15(19)14-9-12(5-6-13(11)14)10-17-18-16(21-22-17)3-2-8-20-18;18-13-5-6-14(19)12-8-10(3-4-11(12)13)9-16-17-15(21-22-16)2-1-7-20-17;18-10-12-4-1-3-11-9-13(6-7-14(11)12)20-17-16-15(21-22-17)5-2-8-19-16;18-10-12-4-1-3-11-9-13(6-7-14(11)12)20-17-15-5-2-8-19-16(15)21-22-17/h3-10H,1,11H2,2H3,(H,26,27);1-3,6-10,13H,4-5,11H2,(H,23,24);3-10H,11H2,1-2H3,(H2,24,25,26);3-10H,2,11H2,1H3,(H,22,23);2-9H,10H2,1H3,(H,21,22);1-8H,9H2,(H,21,22);1-9H,10H2,(H2,20,21,22);1-9H,10H2,(H2,19,20,21,22).

What are the key properties of 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine?

3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine has a molecular weight of 2546.20 g/mol, XLogP of 36.26, 25 rotatable bonds, 11 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 3-[(5-chloro-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(5-cyclopropyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[[5-(3,3-difluorobut-1-en-2-yl)-8-fluoronaphthalen-2-yl]methyl]-2H-pyrazolo[4,3-b]pyridine;1-N-(2,2-difluoropropyl)-1-N-methyl-6-N-(1H-pyrazolo[4,3-b]pyridin-3-yl)isoquinoline-1,6-diamine;3-[(5-ethyl-8-fluoronaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;3-[(8-fluoro-5-methylnaphthalen-2-yl)methyl]-2H-pyrazolo[4,3-b]pyridine;N-[5-(fluoromethyl)naphthalen-2-yl]-1H-pyrazolo[4,3-b]pyridin-3-amine;N-[5-(fluoromethyl)naphthalen-2-yl]-2H-pyrazolo[3,4-b]pyridin-3-amine is sourced from PubChem (CID 161405210), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).