5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate

C134H150F7N37O17S10 — CID 161408648

IUPAC5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate
SMILESCOc1cccc(C(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)c1.COc1ncc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1C.Cc1nc(C(F)(F)F)c(S(=O)(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)s1.Cc1nnc2sc(C(=O)NC3CN(C(=O)Nc4ccc(C(C)C)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(C(=O)Oc4ccc(C(C)(F)F)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(S(=O)(=O)CC(C)(F)F)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(CN4CCCCC4)cc3)c(N)c2c1C
InChIInChI=1S/C22H26N6O2S.C22H27N5OS.C21H21F2N5O3S.C20H21N5O3S.C17H17F3N6O3S3.C17H19N5O2S.C15H19F2N5O3S2/c1-11(2)14-5-7-15(8-6-14)25-22(30)28-9-16(10-28)24-20(29)19-18(23)17-12(3)13(4)26-27-21(17)31-19;1-14-15(2)25-26-22-18(14)19(23)20(29-22)21(28)24-12-16-6-8-17(9-7-16)13-27-10-4-3-5-11-27;1-10-11(2)26-27-19-15(10)16(24)17(32-19)18(29)25-13-8-28(9-13)20(30)31-14-6-4-12(5-7-14)21(3,22)23;1-10-11(2)23-24-19-15(10)16(21)17(29-19)18(26)22-13-8-25(9-13)20(27)12-5-4-6-14(7-12)28-3;1-6-7(2)24-25-15-10(6)11(21)12(31-15)14(27)23-9-4-26(5-9)32(28,29)16-13(17(18,19)20)22-8(3)30-16;1-8-5-11(7-20-16(8)24-4)6-19-15(23)14-13(18)12-9(2)10(3)21-22-17(12)25-14;1-7-8(2)20-21-14-10(7)11(18)12(26-14)13(23)19-9-4-22(5-9)27(24,25)6-15(3,16)17/h5-8,11,16H,9-10,23H2,1-4H3,(H,24,29)(H,25,30);6-9H,3-5,10-13,23H2,1-2H3,(H,24,28);4-7,13H,8-9,24H2,1-3H3,(H,25,29);4-7,13H,8-9,21H2,1-3H3,(H,22,26);9H,4-5,21H2,1-3H3,(H,23,27);5,7H,6,18H2,1-4H3,(H,19,23);9H,4-6,18H2,1-3H3,(H,19,23)
InChIKeyVVEJLSISYAPEOD-UHFFFAOYSA-N
MW3004.57 g/mol
LogP19.53
Rot. Bonds30

About 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate

5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate (PubChem CID 161408648) has the molecular formula C134H150F7N37O17S10 and a molecular weight of 3004.57 g/mol. Its IUPAC name is 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate.

Molecular Properties

Compound Name5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate
PubChem CID161408648
Molecular FormulaC134H150F7N37O17S10
Molecular Weight3004.57 g/mol
Exact Mass3001.91
IUPAC Name5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate
SMILESCOc1cccc(C(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)c1.COc1ncc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1C.Cc1nc(C(F)(F)F)c(S(=O)(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)s1.Cc1nnc2sc(C(=O)NC3CN(C(=O)Nc4ccc(C(C)C)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(C(=O)Oc4ccc(C(C)(F)F)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(S(=O)(=O)CC(C)(F)F)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(CN4CCCCC4)cc3)c(N)c2c1C
InChIInChI=1S/C22H26N6O2S.C22H27N5OS.C21H21F2N5O3S.C20H21N5O3S.C17H17F3N6O3S3.C17H19N5O2S.C15H19F2N5O3S2/c1-11(2)14-5-7-15(8-6-14)25-22(30)28-9-16(10-28)24-20(29)19-18(23)17-12(3)13(4)26-27-21(17)31-19;1-14-15(2)25-26-22-18(14)19(23)20(29-22)21(28)24-12-16-6-8-17(9-7-16)13-27-10-4-3-5-11-27;1-10-11(2)26-27-19-15(10)16(24)17(32-19)18(29)25-13-8-28(9-13)20(30)31-14-6-4-12(5-7-14)21(3,22)23;1-10-11(2)23-24-19-15(10)16(21)17(29-19)18(26)22-13-8-25(9-13)20(27)12-5-4-6-14(7-12)28-3;1-6-7(2)24-25-15-10(6)11(21)12(31-15)14(27)23-9-4-26(5-9)32(28,29)16-13(17(18,19)20)22-8(3)30-16;1-8-5-11(7-20-16(8)24-4)6-19-15(23)14-13(18)12-9(2)10(3)21-22-17(12)25-14;1-7-8(2)20-21-14-10(7)11(18)12(26-14)13(23)19-9-4-22(5-9)27(24,25)6-15(3,16)17/h5-8,11,16H,9-10,23H2,1-4H3,(H,24,29)(H,25,30);6-9H,3-5,10-13,23H2,1-2H3,(H,24,28);4-7,13H,8-9,24H2,1-3H3,(H,25,29);4-7,13H,8-9,21H2,1-3H3,(H,22,26);9H,4-5,21H2,1-3H3,(H,23,27);5,7H,6,18H2,1-4H3,(H,19,23);9H,4-6,18H2,1-3H3,(H,19,23)
InChIKeyVVEJLSISYAPEOD-UHFFFAOYSA-N
XLogP19.53
TPSA770.73 Ų
H-Bond Donors15
H-Bond Acceptors49
Rotatable Bonds30
Heavy Atoms205
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003004.57
LogP ≤ 519.53
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1049

Analyze 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate with MolForge

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Frequently Asked Questions

What is the IUPAC name of 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate?
The IUPAC name of 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate (CID 161408648) is 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate.
What is the SMILES notation for 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate?
The canonical SMILES for 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate is COc1cccc(C(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)c1.COc1ncc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1C.Cc1nc(C(F)(F)F)c(S(=O)(=O)N2CC(NC(=O)c3sc4nnc(C)c(C)c4c3N)C2)s1.Cc1nnc2sc(C(=O)NC3CN(C(=O)Nc4ccc(C(C)C)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(C(=O)Oc4ccc(C(C)(F)F)cc4)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NC3CN(S(=O)(=O)CC(C)(F)F)C3)c(N)c2c1C.Cc1nnc2sc(C(=O)NCc3ccc(CN4CCCCC4)cc3)c(N)c2c1C.
What is the InChIKey of 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate?
The InChIKey is VVEJLSISYAPEOD-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H26N6O2S.C22H27N5OS.C21H21F2N5O3S.C20H21N5O3S.C17H17F3N6O3S3.C17H19N5O2S.C15H19F2N5O3S2/c1-11(2)14-5-7-15(8-6-14)25-22(30)28-9-16(10-28)24-20(29)19-18(23)17-12(3)13(4)26-27-21(17)31-19;1-14-15(2)25-26-22-18(14)19(23)20(29-22)21(28)24-12-16-6-8-17(9-7-16)13-27-10-4-3-5-11-27;1-10-11(2)26-27-19-15(10)16(24)17(32-19)18(29)25-13-8-28(9-13)20(30)31-14-6-4-12(5-7-14)21(3,22)23;1-10-11(2)23-24-19-15(10)16(21)17(29-19)18(26)22-13-8-25(9-13)20(27)12-5-4-6-14(7-12)28-3;1-6-7(2)24-25-15-10(6)11(21)12(31-15)14(27)23-9-4-26(5-9)32(28,29)16-13(17(18,19)20)22-8(3)30-16;1-8-5-11(7-20-16(8)24-4)6-19-15(23)14-13(18)12-9(2)10(3)21-22-17(12)25-14;1-7-8(2)20-21-14-10(7)11(18)12(26-14)13(23)19-9-4-22(5-9)27(24,25)6-15(3,16)17/h5-8,11,16H,9-10,23H2,1-4H3,(H,24,29)(H,25,30);6-9H,3-5,10-13,23H2,1-2H3,(H,24,28);4-7,13H,8-9,24H2,1-3H3,(H,25,29);4-7,13H,8-9,21H2,1-3H3,(H,22,26);9H,4-5,21H2,1-3H3,(H,23,27);5,7H,6,18H2,1-4H3,(H,19,23);9H,4-6,18H2,1-3H3,(H,19,23).
What are the key properties of 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate?
5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate has a molecular weight of 3004.57 g/mol, XLogP of 19.53, 30 rotatable bonds, 15 hydrogen bond donors, and 49 hydrogen bond acceptors.
Where does this data come from?
All data for 5-amino-N-[1-(2,2-difluoropropylsulfonyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[[2-methyl-4-(trifluoromethyl)-1,3-thiazol-5-yl]sulfonyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[[4-(piperidin-1-ylmethyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-3,4-dimethyl-N-[1-[(4-propan-2-ylphenyl)carbamoyl]azetidin-3-yl]thieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[1-(3-methoxybenzoyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;5-amino-N-[(6-methoxy-5-methyl-3-pyridinyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide;[4-(1,1-difluoroethyl)phenyl] 3-[(5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carbonyl)amino]azetidine-1-carboxylate is sourced from PubChem (CID 161408648), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).