tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine

C213H204F8N56O12 — CID 161414911

IUPACtert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine
SMILESCc1ccc([C@@H](O)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5nccc45)cn3)CC2)cc1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5ccc(F)cc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)Cc5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3ccnn3c2)cn1
InChIInChI=1S/C29H29N7O2.2C28H25F2N7O2.C28H25F2N7O.C28H27N7O2.C27H23F2N7O.C25H29N7O2.C20H21N7/c1-20-3-5-21(6-4-20)28(37)29(38)35-13-11-34(12-14-35)27-8-7-22(16-30-27)25-15-23(24-17-32-33(2)18-24)19-36-26(25)9-10-31-36;1-34-16-20(15-33-34)19-12-23(25-6-7-32-37(25)17-19)18-2-5-26(31-14-18)35-8-10-36(11-9-35)28(39)27(38)22-4-3-21(29)13-24(22)30;1-34-16-20(15-33-34)19-13-21(24-7-8-32-37(24)17-19)18-5-6-25(31-14-18)35-9-11-36(12-10-35)28(39)27(38)26-22(29)3-2-4-23(26)30;1-34-17-21(16-33-34)20-13-22(26-7-8-32-37(26)18-20)19-5-6-27(31-15-19)35-9-11-36(12-10-35)28(38)14-23-24(29)3-2-4-25(23)30;1-32-18-23(17-31-32)22-15-24(25-9-10-30-35(25)19-22)21-7-8-26(29-16-21)33-11-13-34(14-12-33)28(37)27(36)20-5-3-2-4-6-20;1-33-16-20(15-32-33)19-13-21(24-7-8-31-36(24)17-19)18-5-6-25(30-14-18)34-9-11-35(12-10-34)27(37)26-22(28)3-2-4-23(26)29;1-25(2,3)34-24(33)31-11-9-30(10-12-31)23-6-5-18(14-26-23)21-13-19(20-15-28-29(4)16-20)17-32-22(21)7-8-27-32;1-25-13-17(12-24-25)16-10-18(19-4-5-23-27(19)14-16)15-2-3-20(22-11-15)26-8-6-21-7-9-26/h3-10,15-19,28,37H,11-14H2,1-2H3;2-7,12-17,27,38H,8-11H2,1H3;2-8,13-17,27,38H,9-12H2,1H3;2-8,13,15-18H,9-12,14H2,1H3;2-10,15-19,27,36H,11-14H2,1H3;2-8,13-17H,9-12H2,1H3;5-8,13-17H,9-12H2,1-4H3;2-5,10-14,21H,6-9H2,1H3/t28-;;;;27-;;;/m1...1.../s1
InChIKeyVVYLPJQWSBNSIX-RSWVMFTISA-N
MW3892.34 g/mol
LogP27.64
Rot. Bonds35

About tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine

tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine (PubChem CID 161414911) has the molecular formula C213H204F8N56O12 and a molecular weight of 3892.34 g/mol. Its IUPAC name is tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine.

Molecular Properties

Compound Nametert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine
PubChem CID161414911
Molecular FormulaC213H204F8N56O12
Molecular Weight3892.34 g/mol
Exact Mass3889.69
IUPAC Nametert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine
SMILESCc1ccc([C@@H](O)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5nccc45)cn3)CC2)cc1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5ccc(F)cc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)Cc5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3ccnn3c2)cn1
InChIInChI=1S/C29H29N7O2.2C28H25F2N7O2.C28H25F2N7O.C28H27N7O2.C27H23F2N7O.C25H29N7O2.C20H21N7/c1-20-3-5-21(6-4-20)28(37)29(38)35-13-11-34(12-14-35)27-8-7-22(16-30-27)25-15-23(24-17-32-33(2)18-24)19-36-26(25)9-10-31-36;1-34-16-20(15-33-34)19-12-23(25-6-7-32-37(25)17-19)18-2-5-26(31-14-18)35-8-10-36(11-9-35)28(39)27(38)22-4-3-21(29)13-24(22)30;1-34-16-20(15-33-34)19-13-21(24-7-8-32-37(24)17-19)18-5-6-25(31-14-18)35-9-11-36(12-10-35)28(39)27(38)26-22(29)3-2-4-23(26)30;1-34-17-21(16-33-34)20-13-22(26-7-8-32-37(26)18-20)19-5-6-27(31-15-19)35-9-11-36(12-10-35)28(38)14-23-24(29)3-2-4-25(23)30;1-32-18-23(17-31-32)22-15-24(25-9-10-30-35(25)19-22)21-7-8-26(29-16-21)33-11-13-34(14-12-33)28(37)27(36)20-5-3-2-4-6-20;1-33-16-20(15-32-33)19-13-21(24-7-8-31-36(24)17-19)18-5-6-25(30-14-18)34-9-11-35(12-10-34)27(37)26-22(28)3-2-4-23(26)29;1-25(2,3)34-24(33)31-11-9-30(10-12-31)23-6-5-18(14-26-23)21-13-19(20-15-28-29(4)16-20)17-32-22(21)7-8-27-32;1-25-13-17(12-24-25)16-10-18(19-4-5-23-27(19)14-16)15-2-3-20(22-11-15)26-8-6-21-7-9-26/h3-10,15-19,28,37H,11-14H2,1-2H3;2-7,12-17,27,38H,8-11H2,1H3;2-8,13-17,27,38H,9-12H2,1H3;2-8,13,15-18H,9-12,14H2,1H3;2-10,15-19,27,36H,11-14H2,1H3;2-8,13-17H,9-12H2,1H3;5-8,13-17H,9-12H2,1-4H3;2-5,10-14,21H,6-9H2,1H3/t28-;;;;27-;;;/m1...1.../s1
InChIKeyVVYLPJQWSBNSIX-RSWVMFTISA-N
XLogP27.64
TPSA654.35 Ų
H-Bond Donors5
H-Bond Acceptors61
Rotatable Bonds35
Heavy Atoms289
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003892.34
LogP ≤ 527.64
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1061

Analyze tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine with MolForge

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Frequently Asked Questions

What is the IUPAC name of tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine?
The IUPAC name of tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine (CID 161414911) is tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine.
What is the SMILES notation for tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine?
The canonical SMILES for tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine is Cc1ccc([C@@H](O)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5nccc45)cn3)CC2)cc1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C(O)c5ccc(F)cc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)Cc5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)c5c(F)cccc5F)CC4)nc3)c3ccnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3ccnn3c2)cn1.
What is the InChIKey of tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine?
The InChIKey is VVYLPJQWSBNSIX-RSWVMFTISA-N. The full InChI is InChI=1S/C29H29N7O2.2C28H25F2N7O2.C28H25F2N7O.C28H27N7O2.C27H23F2N7O.C25H29N7O2.C20H21N7/c1-20-3-5-21(6-4-20)28(37)29(38)35-13-11-34(12-14-35)27-8-7-22(16-30-27)25-15-23(24-17-32-33(2)18-24)19-36-26(25)9-10-31-36;1-34-16-20(15-33-34)19-12-23(25-6-7-32-37(25)17-19)18-2-5-26(31-14-18)35-8-10-36(11-9-35)28(39)27(38)22-4-3-21(29)13-24(22)30;1-34-16-20(15-33-34)19-13-21(24-7-8-32-37(24)17-19)18-5-6-25(31-14-18)35-9-11-36(12-10-35)28(39)27(38)26-22(29)3-2-4-23(26)30;1-34-17-21(16-33-34)20-13-22(26-7-8-32-37(26)18-20)19-5-6-27(31-15-19)35-9-11-36(12-10-35)28(38)14-23-24(29)3-2-4-25(23)30;1-32-18-23(17-31-32)22-15-24(25-9-10-30-35(25)19-22)21-7-8-26(29-16-21)33-11-13-34(14-12-33)28(37)27(36)20-5-3-2-4-6-20;1-33-16-20(15-32-33)19-13-21(24-7-8-31-36(24)17-19)18-5-6-25(30-14-18)34-9-11-35(12-10-34)27(37)26-22(28)3-2-4-23(26)29;1-25(2,3)34-24(33)31-11-9-30(10-12-31)23-6-5-18(14-26-23)21-13-19(20-15-28-29(4)16-20)17-32-22(21)7-8-27-32;1-25-13-17(12-24-25)16-10-18(19-4-5-23-27(19)14-16)15-2-3-20(22-11-15)26-8-6-21-7-9-26/h3-10,15-19,28,37H,11-14H2,1-2H3;2-7,12-17,27,38H,8-11H2,1H3;2-8,13-17,27,38H,9-12H2,1H3;2-8,13,15-18H,9-12,14H2,1H3;2-10,15-19,27,36H,11-14H2,1H3;2-8,13-17H,9-12H2,1H3;5-8,13-17H,9-12H2,1-4H3;2-5,10-14,21H,6-9H2,1H3/t28-;;;;27-;;;/m1...1.../s1.
What are the key properties of tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine?
tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine has a molecular weight of 3892.34 g/mol, XLogP of 27.64, 35 rotatable bonds, 5 hydrogen bond donors, and 61 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl 4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazine-1-carboxylate;2-(2,4-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;2-(2,6-difluorophenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2,6-difluorophenyl)-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]methanone;(2R)-2-hydroxy-2-(4-methylphenyl)-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;6-(1-methylpyrazol-4-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine is sourced from PubChem (CID 161414911), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).