[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone

C105H100Cl8N18O10 — CID 161451488

About [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone

[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone (PubChem CID 161451488) has the molecular formula C105H100Cl8N18O10 and a molecular weight of 2057.69 g/mol. Its IUPAC name is [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone.

Molecular Properties

• Compound Name: [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone
• PubChem CID: 161451488
• Molecular Formula: C105H100Cl8N18O10
• Molecular Weight: 2057.69 g/mol
• Exact Mass: 2052.54
• IUPAC Name: [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone
• SMILES: CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(N(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(O)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCOCC4)cc3)c2c1)c1c(Cl)cncc1Cl
• InChI: InChI=1S/C28H29Cl2N5O2.C26H25Cl2N5O2.C26H24Cl2N4O3.C25H22Cl2N4O3/c1-17(26-23(29)15-31-16-24(26)30)37-21-8-9-25-22(14-21)27(33-32-25)18-4-6-19(7-5-18)28(36)35-12-10-20(11-13-35)34(2)3;1-16(24-21(27)14-29-15-22(24)28)35-19-7-8-23-20(13-19)25(31-30-23)17-3-5-18(6-4-17)26(34)33-11-9-32(2)10-12-33;1-15(24-21(27)13-29-14-22(24)28)35-19-6-7-23-20(12-19)25(31-30-23)16-2-4-17(5-3-16)26(34)32-10-8-18(33)9-11-32;1-15(23-20(26)13-28-14-21(23)27)34-18-6-7-22-19(12-18)24(30-29-22)16-2-4-17(5-3-16)25(32)31-8-10-33-11-9-31/h4-9,14-17,20H,10-13H2,1-3H3,(H,32,33);3-8,13-16H,9-12H2,1-2H3,(H,30,31);2-7,12-15,18,33H,8-11H2,1H3,(H,30,31);2-7,12-15H,8-11H2,1H3,(H,29,30)
• InChIKey: WAOZARQFZOELGM-UHFFFAOYSA-N
• XLogP: 22.91
• TPSA: 320.38 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 20
• Rotatable Bonds: 21
• Heavy Atoms: 141
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2057.69
LogP ≤ 5	22.91
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone?

The IUPAC name of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone (CID 161451488) is [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone.

What is the SMILES notation for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone?

The canonical SMILES for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone is CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(N(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(O)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCOCC4)cc3)c2c1)c1c(Cl)cncc1Cl.

What is the InChIKey of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone?

The InChIKey is WAOZARQFZOELGM-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29Cl2N5O2.C26H25Cl2N5O2.C26H24Cl2N4O3.C25H22Cl2N4O3/c1-17(26-23(29)15-31-16-24(26)30)37-21-8-9-25-22(14-21)27(33-32-25)18-4-6-19(7-5-18)28(36)35-12-10-20(11-13-35)34(2)3;1-16(24-21(27)14-29-15-22(24)28)35-19-7-8-23-20(13-19)25(31-30-23)17-3-5-18(6-4-17)26(34)33-11-9-32(2)10-12-33;1-15(24-21(27)13-29-14-22(24)28)35-19-6-7-23-20(12-19)25(31-30-23)16-2-4-17(5-3-16)26(34)32-10-8-18(33)9-11-32;1-15(23-20(26)13-28-14-21(23)27)34-18-6-7-22-19(12-18)24(30-29-22)16-2-4-17(5-3-16)25(32)31-8-10-33-11-9-31/h4-9,14-17,20H,10-13H2,1-3H3,(H,32,33);3-8,13-16H,9-12H2,1-2H3,(H,30,31);2-7,12-15,18,33H,8-11H2,1H3,(H,30,31);2-7,12-15H,8-11H2,1H3,(H,29,30).

What are the key properties of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone?

[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone has a molecular weight of 2057.69 g/mol, XLogP of 22.91, 21 rotatable bonds, 5 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-hydroxypiperidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-morpholin-4-ylmethanone is sourced from PubChem (CID 161451488), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).