3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide

C137H160F6N24O7S6 — CID 161484119

About 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide

3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 161484119) has the molecular formula C137H160F6N24O7S6 and a molecular weight of 2561.34 g/mol. Its IUPAC name is 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 161484119
• Molecular Formula: C137H160F6N24O7S6
• Molecular Weight: 2561.34 g/mol
• Exact Mass: 2559.11
• IUPAC Name: 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide
• SMILES: COc1cc(N2CCCCC2)ccc1CCNC(=O)c1sc2nc(C)ccc2c1N.Cc1ccc2c(N)c(C(=O)NCCc3cc(F)c(N4CCCCC4)c(F)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(C(F)(F)F)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(C4CC4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)cc3F)sc2n1.Cc1ccc2c(n1)CS(C(=O)NCCc1ccc(N3CCCCC3)cc1)=C2N
• InChI: InChI=1S/C25H30N4OS.C23H25F3N4OS.C23H28N4O2S.C22H24F2N4OS.C22H25FN4OS.C22H28N4OS/c1-16-5-9-19-22(26)23(31-25(19)28-16)24(30)27-12-11-17-6-10-21(20(15-17)18-7-8-18)29-13-3-2-4-14-29;1-14-5-7-16-19(27)20(32-22(16)29-14)21(31)28-10-9-15-6-8-18(17(13-15)23(24,25)26)30-11-3-2-4-12-30;1-15-6-9-18-20(24)21(30-23(18)26-15)22(28)25-11-10-16-7-8-17(14-19(16)29-2)27-12-4-3-5-13-27;1-13-5-6-15-18(25)20(30-22(15)27-13)21(29)26-8-7-14-11-16(23)19(17(24)12-14)28-9-3-2-4-10-28;1-14-5-8-17-19(24)20(29-22(17)26-14)21(28)25-10-9-15-6-7-16(13-18(15)23)27-11-3-2-4-12-27;1-16-5-10-19-20(25-16)15-28(21(19)23)22(27)24-12-11-17-6-8-18(9-7-17)26-13-3-2-4-14-26/h5-6,9-10,15,18H,2-4,7-8,11-14,26H2,1H3,(H,27,30);5-8,13H,2-4,9-12,27H2,1H3,(H,28,31);6-9,14H,3-5,10-13,24H2,1-2H3,(H,25,28);5-6,11-12H,2-4,7-10,25H2,1H3,(H,26,29);5-8,13H,2-4,9-12,24H2,1H3,(H,25,28);5-10H,2-4,11-15,23H2,1H3,(H,24,27)
• InChIKey: WETFKXYLNRFLRA-UHFFFAOYSA-N
• XLogP: 26.62
• TPSA: 436.73 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 30
• Rotatable Bonds: 31
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2561.34
LogP ≤ 5	26.62
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'}, {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'}, {'alert_name': 'thioester', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide (CID 161484119) is 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide is COc1cc(N2CCCCC2)ccc1CCNC(=O)c1sc2nc(C)ccc2c1N.Cc1ccc2c(N)c(C(=O)NCCc3cc(F)c(N4CCCCC4)c(F)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(C(F)(F)F)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)c(C4CC4)c3)sc2n1.Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCCCC4)cc3F)sc2n1.Cc1ccc2c(n1)CS(C(=O)NCCc1ccc(N3CCCCC3)cc1)=C2N.

What is the InChIKey of 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is WETFKXYLNRFLRA-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H30N4OS.C23H25F3N4OS.C23H28N4O2S.C22H24F2N4OS.C22H25FN4OS.C22H28N4OS/c1-16-5-9-19-22(26)23(31-25(19)28-16)24(30)27-12-11-17-6-10-21(20(15-17)18-7-8-18)29-13-3-2-4-14-29;1-14-5-7-16-19(27)20(32-22(16)29-14)21(31)28-10-9-15-6-8-18(17(13-15)23(24,25)26)30-11-3-2-4-12-30;1-15-6-9-18-20(24)21(30-23(18)26-15)22(28)25-11-10-16-7-8-17(14-19(16)29-2)27-12-4-3-5-13-27;1-13-5-6-15-18(25)20(30-22(15)27-13)21(29)26-8-7-14-11-16(23)19(17(24)12-14)28-9-3-2-4-10-28;1-14-5-8-17-19(24)20(29-22(17)26-14)21(28)25-10-9-15-6-7-16(13-18(15)23)27-11-3-2-4-12-27;1-16-5-10-19-20(25-16)15-28(21(19)23)22(27)24-12-11-17-6-8-18(9-7-17)26-13-3-2-4-14-26/h5-6,9-10,15,18H,2-4,7-8,11-14,26H2,1H3,(H,27,30);5-8,13H,2-4,9-12,27H2,1H3,(H,28,31);6-9,14H,3-5,10-13,24H2,1-2H3,(H,25,28);5-6,11-12H,2-4,7-10,25H2,1H3,(H,26,29);5-8,13H,2-4,9-12,24H2,1H3,(H,25,28);5-10H,2-4,11-15,23H2,1H3,(H,24,27).

What are the key properties of 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide?

3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2561.34 g/mol, XLogP of 26.62, 31 rotatable bonds, 12 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-[2-(3-cyclopropyl-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(3,5-difluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-fluoro-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;3-amino-N-[2-(2-methoxy-4-piperidin-1-ylphenyl)ethyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide;5-amino-2-methyl-N-[2-(4-piperidin-1-ylphenyl)ethyl]-7H-thieno[3,4-b]pyridine-6-carboxamide;3-amino-6-methyl-N-[2-[4-piperidin-1-yl-3-(trifluoromethyl)phenyl]ethyl]thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 161484119), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).