N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one

C208H220ClF9N28O27S — CID 161489686

IUPACN-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
SMILESCc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2cccc(C(C)(C)S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C3CC3)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2Cl)cc1=O
InChIInChI=1S/C29H31N3O3.C28H32N2O4.C27H32N4O5S.C26H25F3N2O3.C26H26F2N2O3.C25H27N5O3.C24H25F2N5O3.C23H22ClF2N5O3/c1-20-8-9-22(26(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-27(31(4)28(34)18-23)32-10-12-35-13-11-32;1-19-8-9-21(25(31)15-20-6-5-7-23(14-20)28(2,3)33)16-24(19)22-17-26(29(4)27(32)18-22)30-10-12-34-13-11-30;1-18-23(20-14-24(30(4)25(32)15-20)31-9-11-36-12-10-31)16-22(17-28-18)29-26(33)19-7-6-8-21(13-19)27(2,3)37(5,34)35;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-17-6-7-19(23(31)13-18-4-3-5-20(12-18)26(27)28)14-22(17)21-15-24(29(2)25(32)16-21)30-8-10-33-11-9-30;1-16-21(19-12-23(29(2)24(31)13-19)30-7-9-33-10-8-30)14-20(15-27-16)28-25(32)18-5-6-26-22(11-18)17-3-4-17;1-15-19(17-11-21(30(3)22(32)12-17)31-6-8-34-9-7-31)13-18(14-28-15)29-23(33)16-4-5-27-20(10-16)24(2,25)26;1-23(25,26)18-9-14(3-4-27-18)22(33)29-16-12-17(21(24)28-13-16)15-10-19(30(2)20(32)11-15)31-5-7-34-8-6-31/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-18,33H,10-13,15H2,1-4H3;6-8,13-17H,9-12H2,1-5H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;3-7,12,14-16,26H,8-11,13H2,1-2H3;5-6,11-15,17H,3-4,7-10H2,1-2H3,(H,28,32);4-5,10-14H,6-9H2,1-3H3,(H,29,33);3-4,9-13H,5-8H2,1-2H3,(H,29,33)
InChIKeyWFLDTHYOUYQNDX-UHFFFAOYSA-N
MW3782.72 g/mol
LogP30.76
Rot. Bonds44

About N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one

N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one (PubChem CID 161489686) has the molecular formula C208H220ClF9N28O27S and a molecular weight of 3782.72 g/mol. Its IUPAC name is N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one.

Molecular Properties

Compound NameN-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
PubChem CID161489686
Molecular FormulaC208H220ClF9N28O27S
Molecular Weight3782.72 g/mol
Exact Mass3779.60
IUPAC NameN-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one
SMILESCc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2cccc(C(C)(C)S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C3CC3)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2Cl)cc1=O
InChIInChI=1S/C29H31N3O3.C28H32N2O4.C27H32N4O5S.C26H25F3N2O3.C26H26F2N2O3.C25H27N5O3.C24H25F2N5O3.C23H22ClF2N5O3/c1-20-8-9-22(26(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-27(31(4)28(34)18-23)32-10-12-35-13-11-32;1-19-8-9-21(25(31)15-20-6-5-7-23(14-20)28(2,3)33)16-24(19)22-17-26(29(4)27(32)18-22)30-10-12-34-13-11-30;1-18-23(20-14-24(30(4)25(32)15-20)31-9-11-36-12-10-31)16-22(17-28-18)29-26(33)19-7-6-8-21(13-19)27(2,3)37(5,34)35;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-17-6-7-19(23(31)13-18-4-3-5-20(12-18)26(27)28)14-22(17)21-15-24(29(2)25(32)16-21)30-8-10-33-11-9-30;1-16-21(19-12-23(29(2)24(31)13-19)30-7-9-33-10-8-30)14-20(15-27-16)28-25(32)18-5-6-26-22(11-18)17-3-4-17;1-15-19(17-11-21(30(3)22(32)12-17)31-6-8-34-9-7-31)13-18(14-28-15)29-23(33)16-4-5-27-20(10-16)24(2,25)26;1-23(25,26)18-9-14(3-4-27-18)22(33)29-16-12-17(21(24)28-13-16)15-10-19(30(2)20(32)11-15)31-5-7-34-8-6-31/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-18,33H,10-13,15H2,1-4H3;6-8,13-17H,9-12H2,1-5H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;3-7,12,14-16,26H,8-11,13H2,1-2H3;5-6,11-15,17H,3-4,7-10H2,1-2H3,(H,28,32);4-5,10-14H,6-9H2,1-3H3,(H,29,33);3-4,9-13H,5-8H2,1-2H3,(H,29,33)
InChIKeyWFLDTHYOUYQNDX-UHFFFAOYSA-N
XLogP30.76
TPSA628.83 Ų
H-Bond Donors5
H-Bond Acceptors51
Rotatable Bonds44
Heavy Atoms274
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003782.72
LogP ≤ 530.76
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1051

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'dyes5A(27)', 'substructure': 'N/A'}, {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one with MolForge

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Launch Full Analysis

Related Compounds

2-(1-cyano-1-fluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;1-ethyl-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-3-methylsulfonylbenzamide;N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-propan-2-ylpyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 162096666
N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-methylsulfonylbenzamide;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide
CID 162236294

Frequently Asked Questions

What is the IUPAC name of N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The IUPAC name of N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one (CID 161489686) is N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one.
What is the SMILES notation for N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The canonical SMILES for N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one is Cc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2cccc(C(C)(C)S(C)(=O)=O)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cc1ncc(NC(=O)c2ccnc(C3CC3)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.Cn1c(N2CCOCC2)cc(-c2cc(NC(=O)c3ccnc(C(C)(F)F)c3)cnc2Cl)cc1=O.
What is the InChIKey of N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
The InChIKey is WFLDTHYOUYQNDX-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H31N3O3.C28H32N2O4.C27H32N4O5S.C26H25F3N2O3.C26H26F2N2O3.C25H27N5O3.C24H25F2N5O3.C23H22ClF2N5O3/c1-20-8-9-22(26(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-27(31(4)28(34)18-23)32-10-12-35-13-11-32;1-19-8-9-21(25(31)15-20-6-5-7-23(14-20)28(2,3)33)16-24(19)22-17-26(29(4)27(32)18-22)30-10-12-34-13-11-30;1-18-23(20-14-24(30(4)25(32)15-20)31-9-11-36-12-10-31)16-22(17-28-18)29-26(33)19-7-6-8-21(13-19)27(2,3)37(5,34)35;1-17-6-7-19(23(32)13-18-4-3-5-21(12-18)26(27,28)29)14-22(17)20-15-24(30(2)25(33)16-20)31-8-10-34-11-9-31;1-17-6-7-19(23(31)13-18-4-3-5-20(12-18)26(27)28)14-22(17)21-15-24(29(2)25(32)16-21)30-8-10-33-11-9-30;1-16-21(19-12-23(29(2)24(31)13-19)30-7-9-33-10-8-30)14-20(15-27-16)28-25(32)18-5-6-26-22(11-18)17-3-4-17;1-15-19(17-11-21(30(3)22(32)12-17)31-6-8-34-9-7-31)13-18(14-28-15)29-23(33)16-4-5-27-20(10-16)24(2,25)26;1-23(25,26)18-9-14(3-4-27-18)22(33)29-16-12-17(21(24)28-13-16)15-10-19(30(2)20(32)11-15)31-5-7-34-8-6-31/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-18,33H,10-13,15H2,1-4H3;6-8,13-17H,9-12H2,1-5H3,(H,29,33);3-7,12,14-16H,8-11,13H2,1-2H3;3-7,12,14-16,26H,8-11,13H2,1-2H3;5-6,11-15,17H,3-4,7-10H2,1-2H3,(H,28,32);4-5,10-14H,6-9H2,1-3H3,(H,29,33);3-4,9-13H,5-8H2,1-2H3,(H,29,33).
What are the key properties of N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one?
N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one has a molecular weight of 3782.72 g/mol, XLogP of 30.76, 44 rotatable bonds, 5 hydrogen bond donors, and 51 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-chloro-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;4-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;4-[5-[2-[3-(2-hydroxypropan-2-yl)phenyl]acetyl]-2-methylphenyl]-1-methyl-6-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;N-[6-methyl-5-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)-3-pyridinyl]-3-(2-methylsulfonylpropan-2-yl)benzamide;1-methyl-4-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-6-morpholin-4-ylpyridin-2-one is sourced from PubChem (CID 161489686), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).