N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide

C61H48F3N19O6 — CID 162009179

IUPACN-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide
SMILESCn1cc(NC(=O)c2cccc(-c3cc[nH]c(=O)c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3ccc(=O)[nH]c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3cncc(OCC(F)(F)F)c3)n2)c(-c2cnccn2)n1
InChIInChI=1S/C21H16F3N7O2.2C20H16N6O2/c1-31-11-18(19(30-31)17-10-25-5-6-27-17)29-20(32)16-4-2-3-15(28-16)13-7-14(9-26-8-13)33-12-21(22,23)24;1-26-12-17(19(25-26)15-5-2-3-10-21-15)24-20(28)16-7-4-6-14(23-16)13-8-9-18(27)22-11-13;1-26-12-17(19(25-26)15-5-2-3-9-21-15)24-20(28)16-7-4-6-14(23-16)13-8-10-22-18(27)11-13/h2-11H,12H2,1H3,(H,29,32);2*2-12H,1H3,(H,22,27)(H,24,28)
InChIKeyYTFXZMOVZNSMCA-UHFFFAOYSA-N
MW1200.18 g/mol
LogP8.50
Rot. Bonds14

About N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide

N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide (PubChem CID 162009179) has the molecular formula C61H48F3N19O6 and a molecular weight of 1200.18 g/mol. Its IUPAC name is N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide.

Molecular Properties

Compound NameN-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide
PubChem CID162009179
Molecular FormulaC61H48F3N19O6
Molecular Weight1200.18 g/mol
Exact Mass1199.40
IUPAC NameN-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide
SMILESCn1cc(NC(=O)c2cccc(-c3cc[nH]c(=O)c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3ccc(=O)[nH]c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3cncc(OCC(F)(F)F)c3)n2)c(-c2cnccn2)n1
InChIInChI=1S/C21H16F3N7O2.2C20H16N6O2/c1-31-11-18(19(30-31)17-10-25-5-6-27-17)29-20(32)16-4-2-3-15(28-16)13-7-14(9-26-8-13)33-12-21(22,23)24;1-26-12-17(19(25-26)15-5-2-3-10-21-15)24-20(28)16-7-4-6-14(23-16)13-8-9-18(27)22-11-13;1-26-12-17(19(25-26)15-5-2-3-9-21-15)24-20(28)16-7-4-6-14(23-16)13-8-10-22-18(27)11-13/h2-11H,12H2,1H3,(H,29,32);2*2-12H,1H3,(H,22,27)(H,24,28)
InChIKeyYTFXZMOVZNSMCA-UHFFFAOYSA-N
XLogP8.50
TPSA318.83 Ų
H-Bond Donors5
H-Bond Acceptors20
Rotatable Bonds14
Heavy Atoms89
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001200.18
LogP ≤ 58.50
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1020

Analyze N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-[2-[2-[2-[2-[[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
CID 57402366
N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methylpyridin-3-yl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 90456408
N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-ylpyridazin-3-yl]-6-methylpyridin-3-yl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 90456521
N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-ylpyridazin-3-yl]-6-methylpyridin-3-yl]-2-(1,1-difluoropropyl)pyridine-4-carboxamide
CID 90456591
2-(1,1-difluoropropyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methylpyridin-3-yl]pyridine-4-carboxamide
CID 90456930
N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]pyridin-3-yl]-4-(trifluoromethyl)pyridine-2-carboxamide
CID 90461189
2-(2-fluoropropan-2-yl)-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]-3-pyridinyl]pyridine-4-carboxamide
CID 117609656
2-(1,1-difluoroethyl)-N-(6-methyl-5-(5-morpholino-6-((tetrahydro-2H-pyran-4-yl)oxy)pyridazin-3-yl)pyridin-3-yl)isonicotinamide
CID 117609844
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-[2-[2-[2-[2-[[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
CID 57398875
2-(1,1-difluoropropyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methylpyridin-3-yl]pyridine-4-carboxamide
CID 90456865
2-(2,6-Dioxopiperidin-3-yl)-5-[2-[2-[4-[[4-[4-[4-[3-(2-methylpropoxy)-4-pyridinyl]pyrazol-1-yl]phenyl]piperazin-1-yl]methyl]triazol-1-yl]ethoxy]ethylamino]isoindole-1,3-dione
CID 177644409
2-(2,6-Dioxopiperidin-3-yl)-5-[7-[4-[[4-[4-[4-[3-(2-methylpropoxy)-4-pyridinyl]pyrazol-1-yl]phenyl]piperazin-1-yl]methyl]triazol-1-yl]heptylamino]isoindole-1,3-dione
CID 177653345

Frequently Asked Questions

What is the IUPAC name of N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide?
The IUPAC name of N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide (CID 162009179) is N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide.
What is the SMILES notation for N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide?
The canonical SMILES for N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide is Cn1cc(NC(=O)c2cccc(-c3cc[nH]c(=O)c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3ccc(=O)[nH]c3)n2)c(-c2ccccn2)n1.Cn1cc(NC(=O)c2cccc(-c3cncc(OCC(F)(F)F)c3)n2)c(-c2cnccn2)n1.
What is the InChIKey of N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide?
The InChIKey is YTFXZMOVZNSMCA-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H16F3N7O2.2C20H16N6O2/c1-31-11-18(19(30-31)17-10-25-5-6-27-17)29-20(32)16-4-2-3-15(28-16)13-7-14(9-26-8-13)33-12-21(22,23)24;1-26-12-17(19(25-26)15-5-2-3-10-21-15)24-20(28)16-7-4-6-14(23-16)13-8-9-18(27)22-11-13;1-26-12-17(19(25-26)15-5-2-3-9-21-15)24-20(28)16-7-4-6-14(23-16)13-8-10-22-18(27)11-13/h2-11H,12H2,1H3,(H,29,32);2*2-12H,1H3,(H,22,27)(H,24,28).
What are the key properties of N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide?
N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide has a molecular weight of 1200.18 g/mol, XLogP of 8.50, 14 rotatable bonds, 5 hydrogen bond donors, and 20 hydrogen bond acceptors.
Where does this data come from?
All data for N-(1-methyl-3-pyrazin-2-ylpyrazol-4-yl)-6-[5-(2,2,2-trifluoroethoxy)-3-pyridinyl]pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(2-oxo-1H-pyridin-4-yl)pyridine-2-carboxamide;N-(1-methyl-3-pyridin-2-ylpyrazol-4-yl)-6-(6-oxo-1H-pyridin-3-yl)pyridine-2-carboxamide is sourced from PubChem (CID 162009179), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).