2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C76H93F3N32O8 — CID 162024887

IUPAC2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCOc1ccncc1NC(=O)c1c(N)nn2ccc(N(C)CC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCNC(C(F)(F)F)C3)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCCN3CCCC3)nc12
InChIInChI=1S/C20H26N8O2.2C19H24N8O2.C18H19F3N8O2/c1-26-9-4-5-13(26)12-27(2)16-7-10-28-19(24-16)17(18(21)25-28)20(29)23-14-11-22-8-6-15(14)30-3;1-26-8-3-4-12(26)10-22-15-6-9-27-18(24-15)16(17(20)25-27)19(28)23-13-11-21-7-5-14(13)29-2;1-29-14-4-6-21-12-13(14)23-19(28)16-17(20)25-27-10-5-15(24-18(16)27)22-7-11-26-8-2-3-9-26;1-31-11-2-4-23-8-10(11)25-17(30)14-15(22)27-29-6-3-13(26-16(14)29)28-7-5-24-12(9-28)18(19,20)21/h6-8,10-11,13H,4-5,9,12H2,1-3H3,(H2,21,25)(H,23,29);5-7,9,11-12H,3-4,8,10H2,1-2H3,(H2,20,25)(H,22,24)(H,23,28);4-6,10,12H,2-3,7-9,11H2,1H3,(H2,20,25)(H,22,24)(H,23,28);2-4,6,8,12,24H,5,7,9H2,1H3,(H2,22,27)(H,25,30)
InChIKeyYVFWFCLZVHNPOI-UHFFFAOYSA-N
MW1639.79 g/mol
LogP5.75
Rot. Bonds23

About 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 162024887) has the molecular formula C76H93F3N32O8 and a molecular weight of 1639.79 g/mol. Its IUPAC name is 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound Name2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID162024887
Molecular FormulaC76H93F3N32O8
Molecular Weight1639.79 g/mol
Exact Mass1638.78
IUPAC Name2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCOc1ccncc1NC(=O)c1c(N)nn2ccc(N(C)CC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCNC(C(F)(F)F)C3)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCCN3CCCC3)nc12
InChIInChI=1S/C20H26N8O2.2C19H24N8O2.C18H19F3N8O2/c1-26-9-4-5-13(26)12-27(2)16-7-10-28-19(24-16)17(18(21)25-28)20(29)23-14-11-22-8-6-15(14)30-3;1-26-8-3-4-12(26)10-22-15-6-9-27-18(24-15)16(17(20)25-27)19(28)23-13-11-21-7-5-14(13)29-2;1-29-14-4-6-21-12-13(14)23-19(28)16-17(20)25-27-10-5-15(24-18(16)27)22-7-11-26-8-2-3-9-26;1-31-11-2-4-23-8-10(11)25-17(30)14-15(22)27-29-6-3-13(26-16(14)29)28-7-5-24-12(9-28)18(19,20)21/h6-8,10-11,13H,4-5,9,12H2,1-3H3,(H2,21,25)(H,23,29);5-7,9,11-12H,3-4,8,10H2,1-2H3,(H2,20,25)(H,22,24)(H,23,28);4-6,10,12H,2-3,7-9,11H2,1H3,(H2,20,25)(H,22,24)(H,23,28);2-4,6,8,12,24H,5,7,9H2,1H3,(H2,22,27)(H,25,30)
InChIKeyYVFWFCLZVHNPOI-UHFFFAOYSA-N
XLogP5.75
TPSA482.01 Ų
H-Bond Donors11
H-Bond Acceptors36
Rotatable Bonds23
Heavy Atoms119
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001639.79
LogP ≤ 55.75
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1036

Analyze 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

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Related Compounds

2-amino-N-[4-[[(3R)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287701
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287702
2-amino-N-[4-[[(3S)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 76287848
2-amino-N-(4-methoxypyridin-3-yl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 78210242
2-amino-N-[4-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302753
2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302754
2-amino-N-[4-(1-methylpiperidin-4-yl)oxypyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86302756
2-amino-N-[4-[(3S)-1-(2-methoxyethyl)piperidin-3-yl]oxypyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304150
2-amino-N-[4-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304308
2-amino-N-[4-[(3S)-1-methylpyrrolidin-3-yl]oxypyridin-3-yl]-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304462
2-amino-N-(4-piperidin-4-yloxypyridin-3-yl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304463
2-amino-N-(4-pyridin-4-yloxypyridin-3-yl)-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86304961

Frequently Asked Questions

What is the IUPAC name of 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 162024887) is 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is COc1ccncc1NC(=O)c1c(N)nn2ccc(N(C)CC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(N3CCNC(C(F)(F)F)C3)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCC3CCCN3C)nc12.COc1ccncc1NC(=O)c1c(N)nn2ccc(NCCN3CCCC3)nc12.
What is the InChIKey of 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is YVFWFCLZVHNPOI-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H26N8O2.2C19H24N8O2.C18H19F3N8O2/c1-26-9-4-5-13(26)12-27(2)16-7-10-28-19(24-16)17(18(21)25-28)20(29)23-14-11-22-8-6-15(14)30-3;1-26-8-3-4-12(26)10-22-15-6-9-27-18(24-15)16(17(20)25-27)19(28)23-13-11-21-7-5-14(13)29-2;1-29-14-4-6-21-12-13(14)23-19(28)16-17(20)25-27-10-5-15(24-18(16)27)22-7-11-26-8-2-3-9-26;1-31-11-2-4-23-8-10(11)25-17(30)14-15(22)27-29-6-3-13(26-16(14)29)28-7-5-24-12(9-28)18(19,20)21/h6-8,10-11,13H,4-5,9,12H2,1-3H3,(H2,21,25)(H,23,29);5-7,9,11-12H,3-4,8,10H2,1-2H3,(H2,20,25)(H,22,24)(H,23,28);4-6,10,12H,2-3,7-9,11H2,1H3,(H2,20,25)(H,22,24)(H,23,28);2-4,6,8,12,24H,5,7,9H2,1H3,(H2,22,27)(H,25,30).
What are the key properties of 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 1639.79 g/mol, XLogP of 5.75, 23 rotatable bonds, 11 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-N-(4-methoxy-3-pyridinyl)-5-[methyl-[(1-methylpyrrolidin-2-yl)methyl]amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[(1-methylpyrrolidin-2-yl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-(4-methoxy-3-pyridinyl)-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 162024887), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).