N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide

C122H133F11N34O13 — CID 162055958

IUPACN-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide
SMILESCCN(C(=O)c1cc(F)cnc1-c1ncccn1)[C@@H](C)COc1cnc(C(C)(F)F)cn1.CCN(C(=O)c1cc(OC)cnc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1.CCN(C(=O)c1cccnc1-n1nccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1ccncc1-n1cccn1)[C@@H](C)COc1ccc(C(C)(F)F)cn1.CCN(C(=O)c1cnccc1-n1cccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1cnccc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1
InChIInChI=1S/C21H21F3N6O2.C21H22F3N5O2.C21H23F2N5O2.C20H21F3N6O2.C20H24N6O3.C19H22N6O2/c1-4-30(13(2)12-32-17-11-27-16(10-28-17)21(3,23)24)20(31)15-8-14(22)9-29-18(15)19-25-6-5-7-26-19;1-4-28(20(30)16-12-25-8-6-18(16)29-9-5-7-27-29)14(2)13-31-19-17(22)10-15(11-26-19)21(3,23)24;1-4-27(15(2)14-30-19-7-6-16(12-25-19)21(3,22)23)20(29)17-8-10-24-13-18(17)28-11-5-9-26-28;1-4-28(19(30)15-6-5-7-24-17(15)29-26-8-9-27-29)13(2)12-31-18-16(21)10-14(11-25-18)20(3,22)23;1-5-25(15(3)13-29-18-7-6-14(2)11-21-18)20(27)17-10-16(28-4)12-22-19(17)26-23-8-9-24-26;1-4-24(15(3)13-27-18-6-5-14(2)11-21-18)19(26)16-12-20-8-7-17(16)25-22-9-10-23-25/h5-11,13H,4,12H2,1-3H3;5-12,14H,4,13H2,1-3H3;5-13,15H,4,14H2,1-3H3;5-11,13H,4,12H2,1-3H3;6-12,15H,5,13H2,1-4H3;5-12,15H,4,13H2,1-3H3/t13-;14-;15-;13-;2*15-/m000000/s1
InChIKeyYZEJBNLKBBTJHM-JMXFCCIDSA-N
MW2492.61 g/mol
LogP18.89
Rot. Bonds47

About N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide

N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide (PubChem CID 162055958) has the molecular formula C122H133F11N34O13 and a molecular weight of 2492.61 g/mol. Its IUPAC name is N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide
PubChem CID162055958
Molecular FormulaC122H133F11N34O13
Molecular Weight2492.61 g/mol
Exact Mass2491.06
IUPAC NameN-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide
SMILESCCN(C(=O)c1cc(F)cnc1-c1ncccn1)[C@@H](C)COc1cnc(C(C)(F)F)cn1.CCN(C(=O)c1cc(OC)cnc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1.CCN(C(=O)c1cccnc1-n1nccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1ccncc1-n1cccn1)[C@@H](C)COc1ccc(C(C)(F)F)cn1.CCN(C(=O)c1cnccc1-n1cccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1cnccc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1
InChIInChI=1S/C21H21F3N6O2.C21H22F3N5O2.C21H23F2N5O2.C20H21F3N6O2.C20H24N6O3.C19H22N6O2/c1-4-30(13(2)12-32-17-11-27-16(10-28-17)21(3,23)24)20(31)15-8-14(22)9-29-18(15)19-25-6-5-7-26-19;1-4-28(20(30)16-12-25-8-6-18(16)29-9-5-7-27-29)14(2)13-31-19-17(22)10-15(11-26-19)21(3,23)24;1-4-27(15(2)14-30-19-7-6-16(12-25-19)21(3,22)23)20(29)17-8-10-24-13-18(17)28-11-5-9-26-28;1-4-28(19(30)15-6-5-7-24-17(15)29-26-8-9-27-29)13(2)12-31-18-16(21)10-14(11-25-18)20(3,22)23;1-5-25(15(3)13-29-18-7-6-14(2)11-21-18)20(27)17-10-16(28-4)12-22-19(17)26-23-8-9-24-26;1-4-24(15(3)13-27-18-6-5-14(2)11-21-18)19(26)16-12-20-8-7-17(16)25-22-9-10-23-25/h5-11,13H,4,12H2,1-3H3;5-12,14H,4,13H2,1-3H3;5-13,15H,4,14H2,1-3H3;5-11,13H,4,12H2,1-3H3;6-12,15H,5,13H2,1-4H3;5-12,15H,4,13H2,1-3H3/t13-;14-;15-;13-;2*15-/m000000/s1
InChIKeyYZEJBNLKBBTJHM-JMXFCCIDSA-N
XLogP18.89
TPSA507.59 Ų
H-Bond Donors
H-Bond Acceptors41
Rotatable Bonds47
Heavy Atoms180
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002492.61
LogP ≤ 518.89
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1041

Analyze N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

6-[(1R)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-[1-[3-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]-3-[5-oxo-3-(2,2,2-trifluoroethoxy)-1,6-naphthyridin-6-yl]propyl]pyrazol-4-yl]-1,6-naphthyridin-5-one
CID 129157542
N-[2-[3-fluoro-2-imino-5-(3-methyl-1,2-oxazol-5-yl)-1-pyridinyl]-2-iminoethyl]-N-[(Z)-2-[3-methyl-5-(1-methylpyrazol-4-yl)-2-pyridinyl]ethenyl]formamide;6-[1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2,2,2-trifluoroethoxy)-1,6-naphthyridin-5-one
CID 143835056
N-ethyl-6-[2-[3-[ethyl-[(2S)-1-[[5-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]carbamoyl]-2-pyridinyl]triazol-4-yl]-5-fluoro-3-(1-methylpyrazol-3-yl)-N-[(2S)-1-[[5-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]pyridine-2-carboxamide
CID 155048123
5-[2-[5-[2-[5-[2-[3-[[(2S)-1-[(5-chloro-2-pyridinyl)oxy]propan-2-yl]-ethylcarbamoyl]-5-fluoro-2-pyridinyl]triazol-4-yl]-3-[ethyl-[(2S)-1-[[5-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]carbamoyl]-2-pyridinyl]triazol-4-yl]-3-[ethyl-[(2S)-1-[[3-fluoro-5-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]carbamoyl]-6-methyl-2-pyridinyl]triazol-4-yl]-N-ethyl-6-methyl-2-(triazol-2-yl)-N-[(2S)-1-[5-(trifluoromethyl)pyrazin-2-yl]oxypropan-2-yl]pyridine-3-carboxamide
CID 155048125
N-ethyl-5-[2-[3-[ethyl-[(2S)-1-[5-(trifluoromethyl)pyrimidin-2-yl]oxypropan-2-yl]carbamoyl]-6-methyl-2-pyridinyl]triazol-4-yl]-6-methyl-2-(triazol-2-yl)-N-[(2S)-1-[[5-(trifluoromethyl)-2-pyridinyl]oxy]propan-2-yl]pyridine-3-carboxamide
CID 155048132
N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-6-methyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-5-fluoro-2-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-fluoro-2-(1-methylpyrazol-3-yl)pyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-5-methyl-3-pyrazol-1-ylpyridine-2-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide
CID 157065681
N-[(2S)-1-[[5-(1,1-difluoroethoxy)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3,5-difluoro-2-(triazol-2-yl)benzamide;N-[(2S)-1-[[5-(1,1-difluoroethoxy)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-fluoro-2-pyrimidin-2-ylbenzamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-fluoro-3-methyl-6-(triazol-2-yl)benzamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-methoxy-2-(triazol-2-yl)benzamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(1-methylpyrazol-4-yl)benzamide;N-ethyl-4-fluoro-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-pyrimidin-2-ylbenzamide
CID 157137243
(7S)-2-(5,6-dimethoxy-3-pyridinyl)-7-ethoxy-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]pyrrolo[3,4-b]pyridin-5-one;(2R)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;(2S)-2'-(5,6-dimethoxy-3-pyridinyl)-4'-methyl-6'-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]spiro[oxolane-2,7'-pyrrolo[3,4-b]pyridine]-5'-one;2-(6-ethoxy-5-methoxy-3-pyridinyl)-7-methoxy-4-methyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7S)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one;(7R)-2-(5-ethoxy-3-pyridinyl)-4,7-dimethyl-6-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-7H-pyrrolo[3,4-b]pyridin-5-one
CID 157162836
3-(cyclopropylmethyl)-8-[[4-(2,4-difluorophenyl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine;[1-(cyclopropylmethyl)-4-(trifluoromethyl)pyrazolo[3,4-b]pyridin-5-yl]-[4-(2,4-difluorophenyl)piperazin-1-yl]methanone;2-[[4-[2-(2-fluoroethoxy)-4-(trifluoromethyl)phenyl]piperidin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridine;2-[[4-[3-methoxy-5-(trifluoromethyl)-2-pyridinyl]-3-methylpiperidin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridine;2-[[(1R,5S)-6-[[3-methoxy-5-(trifluoromethyl)-2-pyridinyl]oxymethyl]-3-azabicyclo[3.1.0]hexan-3-yl]methyl]-1-methylimidazo[4,5-b]pyridine;2-[[4-[3-methoxy-5-(trifluoromethyl)-2-pyridinyl]piperidin-1-yl]methyl]-1-methylimidazo[4,5-b]pyridine;2-[[4-[3-methoxy-5-(trifluoromethyl)-2-pyridinyl]piperidin-1-yl]methyl]-1,3,5-triazatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraene
CID 157176874
(3-Ethoxy-6-methyl-2-pyridinyl)-[2-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone;(3-fluoro-2-pyrimidin-2-ylphenyl)-[2-[5-(trifluoromethyl)pyrimidin-2-yl]oxy-7-azabicyclo[2.2.1]heptan-7-yl]methanone;[3-(triazol-2-yl)-2-pyridinyl]-[2-[[5-(trifluoromethyl)pyrazin-2-yl]methyl]-7-azabicyclo[2.2.1]heptan-7-yl]methanone
CID 157197432
CID 157205339
CID 157205339
1-[4-(4,6-Dimethyl-2-pyridinyl)-1-methylpyrazol-5-yl]-2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[4-(5-fluoro-2-pyridinyl)-1-methylpyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[4-(3-methoxy-2-pyridinyl)-1-methylpyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-(6-methylpyrazin-2-yl)pyrazol-5-yl]ethanone;2-(6-fluoro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-[1-methyl-4-[6-(trifluoromethyl)-2-pyridinyl]pyrazol-5-yl]ethanone
CID 157243843

Frequently Asked Questions

What is the IUPAC name of N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide?
The IUPAC name of N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide (CID 162055958) is N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide.
What is the SMILES notation for N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide?
The canonical SMILES for N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide is CCN(C(=O)c1cc(F)cnc1-c1ncccn1)[C@@H](C)COc1cnc(C(C)(F)F)cn1.CCN(C(=O)c1cc(OC)cnc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1.CCN(C(=O)c1cccnc1-n1nccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1ccncc1-n1cccn1)[C@@H](C)COc1ccc(C(C)(F)F)cn1.CCN(C(=O)c1cnccc1-n1cccn1)[C@@H](C)COc1ncc(C(C)(F)F)cc1F.CCN(C(=O)c1cnccc1-n1nccn1)[C@@H](C)COc1ccc(C)cn1.
What is the InChIKey of N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide?
The InChIKey is YZEJBNLKBBTJHM-JMXFCCIDSA-N. The full InChI is InChI=1S/C21H21F3N6O2.C21H22F3N5O2.C21H23F2N5O2.C20H21F3N6O2.C20H24N6O3.C19H22N6O2/c1-4-30(13(2)12-32-17-11-27-16(10-28-17)21(3,23)24)20(31)15-8-14(22)9-29-18(15)19-25-6-5-7-26-19;1-4-28(20(30)16-12-25-8-6-18(16)29-9-5-7-27-29)14(2)13-31-19-17(22)10-15(11-26-19)21(3,23)24;1-4-27(15(2)14-30-19-7-6-16(12-25-19)21(3,22)23)20(29)17-8-10-24-13-18(17)28-11-5-9-26-28;1-4-28(19(30)15-6-5-7-24-17(15)29-26-8-9-27-29)13(2)12-31-18-16(21)10-14(11-25-18)20(3,22)23;1-5-25(15(3)13-29-18-7-6-14(2)11-21-18)20(27)17-10-16(28-4)12-22-19(17)26-23-8-9-24-26;1-4-24(15(3)13-27-18-6-5-14(2)11-21-18)19(26)16-12-20-8-7-17(16)25-22-9-10-23-25/h5-11,13H,4,12H2,1-3H3;5-12,14H,4,13H2,1-3H3;5-13,15H,4,14H2,1-3H3;5-11,13H,4,12H2,1-3H3;6-12,15H,5,13H2,1-4H3;5-12,15H,4,13H2,1-3H3/t13-;14-;15-;13-;2*15-/m000000/s1.
What are the key properties of N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide?
N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide has a molecular weight of 2492.61 g/mol, XLogP of 18.89, 47 rotatable bonds, 0 hydrogen bond donors, and 41 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-4-pyrazol-1-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-3-fluoro-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-2-(triazol-2-yl)pyridine-3-carboxamide;N-[(2S)-1-[5-(1,1-difluoroethyl)pyrazin-2-yl]oxypropan-2-yl]-N-ethyl-5-fluoro-2-pyrimidin-2-ylpyridine-3-carboxamide;N-[(2S)-1-[[5-(1,1-difluoroethyl)-2-pyridinyl]oxy]propan-2-yl]-N-ethyl-3-pyrazol-1-ylpyridine-4-carboxamide;N-ethyl-5-methoxy-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-2-(triazol-2-yl)pyridine-3-carboxamide;N-ethyl-N-[(2S)-1-[(5-methyl-2-pyridinyl)oxy]propan-2-yl]-4-(triazol-2-yl)pyridine-3-carboxamide is sourced from PubChem (CID 162055958), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).