8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine

C143H185Cl7F2N16O22S3 — CID 162075475

About 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine

8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine (PubChem CID 162075475) has the molecular formula C143H185Cl7F2N16O22S3 and a molecular weight of 2862.51 g/mol. Its IUPAC name is 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine.

Molecular Properties

• Compound Name: 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine
• PubChem CID: 162075475
• Molecular Formula: C143H185Cl7F2N16O22S3
• Molecular Weight: 2862.51 g/mol
• Exact Mass: 2857.08
• IUPAC Name: 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine
• SMILES: CC(C)Cc1cc(OC(C)C)c2ccc(OCCN3CCOCC3)c(Cl)c2n1.CC(C)Nc1nc(-c2cc(OC(C)C)c3ccc(OC[C@@H]4CC(F)(F)CN4C)c(Cl)c3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)C)c3ccc(OC[C@H]4COCCN4)c(Cl)c3n2)cs1.CCCOc1ccc2c(OC(C)C)cc(SCC)nc2c1Cl.CCOc1cc(OC(C)C)c2ccc(OCCOC)c(Cl)c2n1.COCCOc1cc(OC(C)C)c2ccc(OCCOC)c(Cl)c2n1.COCCOc1ccc2c(OC(C)C)cc(-n3ccc(CC(C)C)n3)nc2c1Cl
• InChI: InChI=1S/C24H29ClF2N4O2S.C23H29ClN4O3S.C22H28ClN3O3.C22H31ClN2O3.C18H24ClNO5.C17H22ClNO4.C17H22ClNO2S/c1-13(2)28-23-30-18(11-34-23)17-8-20(33-14(3)4)16-6-7-19(21(25)22(16)29-17)32-10-15-9-24(26,27)12-31(15)5;1-13(2)26-23-28-18(12-32-23)17-9-20(31-14(3)4)16-5-6-19(21(24)22(16)27-17)30-11-15-10-29-8-7-25-15;1-14(2)12-16-8-9-26(25-16)20-13-19(29-15(3)4)17-6-7-18(28-11-10-27-5)21(23)22(17)24-20;1-15(2)13-17-14-20(28-16(3)4)18-5-6-19(21(23)22(18)24-17)27-12-9-25-7-10-26-11-8-25;1-12(2)25-15-11-16(24-10-8-22-4)20-18-13(15)5-6-14(17(18)19)23-9-7-21-3;1-5-21-15-10-14(23-11(2)3)12-6-7-13(22-9-8-20-4)16(18)17(12)19-15;1-5-9-20-13-8-7-12-14(21-11(3)4)10-15(22-6-2)19-17(12)16(13)18/h6-8,11,13-15H,9-10,12H2,1-5H3,(H,28,30);5-6,9,12-15,25H,7-8,10-11H2,1-4H3,(H,26,28);6-9,13-15H,10-12H2,1-5H3;5-6,14-16H,7-13H2,1-4H3;5-6,11-12H,7-10H2,1-4H3;6-7,10-11H,5,8-9H2,1-4H3;7-8,10-11H,5-6,9H2,1-4H3/t2*15-;;;;;/m01...../s1
• InChIKey: ZBQMQAKHMRISJZ-QNQGJNMGSA-N
• XLogP: 34.39
• TPSA: 379.46 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 41
• Rotatable Bonds: 58
• Heavy Atoms: 193
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2862.51
LogP ≤ 5	34.39
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	41

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The IUPAC name of 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine (CID 162075475) is 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine.

What is the SMILES notation for 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The canonical SMILES for 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine is CC(C)Cc1cc(OC(C)C)c2ccc(OCCN3CCOCC3)c(Cl)c2n1.CC(C)Nc1nc(-c2cc(OC(C)C)c3ccc(OC[C@@H]4CC(F)(F)CN4C)c(Cl)c3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)C)c3ccc(OC[C@H]4COCCN4)c(Cl)c3n2)cs1.CCCOc1ccc2c(OC(C)C)cc(SCC)nc2c1Cl.CCOc1cc(OC(C)C)c2ccc(OCCOC)c(Cl)c2n1.COCCOc1cc(OC(C)C)c2ccc(OCCOC)c(Cl)c2n1.COCCOc1ccc2c(OC(C)C)cc(-n3ccc(CC(C)C)n3)nc2c1Cl.

What is the InChIKey of 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The InChIKey is ZBQMQAKHMRISJZ-QNQGJNMGSA-N. The full InChI is InChI=1S/C24H29ClF2N4O2S.C23H29ClN4O3S.C22H28ClN3O3.C22H31ClN2O3.C18H24ClNO5.C17H22ClNO4.C17H22ClNO2S/c1-13(2)28-23-30-18(11-34-23)17-8-20(33-14(3)4)16-6-7-19(21(25)22(16)29-17)32-10-15-9-24(26,27)12-31(15)5;1-13(2)26-23-28-18(12-32-23)17-9-20(31-14(3)4)16-5-6-19(21(24)22(16)27-17)30-11-15-10-29-8-7-25-15;1-14(2)12-16-8-9-26(25-16)20-13-19(29-15(3)4)17-6-7-18(28-11-10-27-5)21(23)22(17)24-20;1-15(2)13-17-14-20(28-16(3)4)18-5-6-19(21(23)22(18)24-17)27-12-9-25-7-10-26-11-8-25;1-12(2)25-15-11-16(24-10-8-22-4)20-18-13(15)5-6-14(17(18)19)23-9-7-21-3;1-5-21-15-10-14(23-11(2)3)12-6-7-13(22-9-8-20-4)16(18)17(12)19-15;1-5-9-20-13-8-7-12-14(21-11(3)4)10-15(22-6-2)19-17(12)16(13)18/h6-8,11,13-15H,9-10,12H2,1-5H3,(H,28,30);5-6,9,12-15,25H,7-8,10-11H2,1-4H3,(H,26,28);6-9,13-15H,10-12H2,1-5H3;5-6,14-16H,7-13H2,1-4H3;5-6,11-12H,7-10H2,1-4H3;6-7,10-11H,5,8-9H2,1-4H3;7-8,10-11H,5-6,9H2,1-4H3/t2*15-;;;;;/m01...../s1.

What are the key properties of 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine has a molecular weight of 2862.51 g/mol, XLogP of 34.39, 58 rotatable bonds, 3 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 8-chloro-2,7-bis(2-methoxyethoxy)-4-propan-2-yloxyquinoline;4-[8-chloro-7-[[(2S)-4,4-difluoro-1-methylpyrrolidin-2-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;8-chloro-2-ethoxy-7-(2-methoxyethoxy)-4-propan-2-yloxyquinoline;8-chloro-2-ethylsulfanyl-4-propan-2-yloxy-7-propoxyquinoline;8-chloro-7-(2-methoxyethoxy)-2-[3-(2-methylpropyl)pyrazol-1-yl]-4-propan-2-yloxyquinoline;4-[2-[8-chloro-2-(2-methylpropyl)-4-propan-2-yloxyquinolin-7-yl]oxyethyl]morpholine;4-[8-chloro-7-[[(3R)-morpholin-3-yl]methoxy]-4-propan-2-yloxyquinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine is sourced from PubChem (CID 162075475), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).