N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide

C125H137F16N11O11 — CID 162078884

IUPACN-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
SMILESCCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2ccc(C(N)=O)nc2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccc(C#N)c2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccnc2C#N)CC1.C[C@H]1C[C@H](c2ccc(C#N)cc2)CC[C@H]1N(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CC1.C[C@](O)(c1ccc(C(=O)N(C2CCC(c3ccccc3F)CC2)C2CC2)cc1)C(F)(F)F
InChIInChI=1S/C27H29F3N2O2.C25H27F4NO2.C25H27F3N2O2.C24H28F3N3O3.C24H26F3N3O2/c1-17-15-21(19-5-3-18(16-31)4-6-19)9-14-24(17)32(23-12-13-23)25(33)20-7-10-22(11-8-20)26(2,34)27(28,29)30;1-24(32,25(27,28)29)18-10-6-17(7-11-18)23(31)30(20-14-15-20)19-12-8-16(9-13-19)21-4-2-3-5-22(21)26;1-3-30(22-13-9-18(10-14-22)20-6-4-5-17(15-20)16-29)23(31)19-7-11-21(12-8-19)24(2,32)25(26,27)28;1-3-30(22(32)16-4-9-18(10-5-16)23(2,33)24(25,26)27)19-11-6-15(7-12-19)17-8-13-20(21(28)31)29-14-17;1-3-30(19-12-8-16(9-13-19)20-5-4-14-29-21(20)15-28)22(31)17-6-10-18(11-7-17)23(2,32)24(25,26)27/h3-8,10-11,17,21,23-24,34H,9,12-15H2,1-2H3;2-7,10-11,16,19-20,32H,8-9,12-15H2,1H3;4-8,11-12,15,18,22,32H,3,9-10,13-14H2,1-2H3;4-5,8-10,13-15,19,33H,3,6-7,11-12H2,1-2H3,(H2,28,31);4-7,10-11,14,16,19,32H,3,8-9,12-13H2,1-2H3/t17-,21+,24+,26-;16?,19?,24-;18?,22?,24-;15?,19?,23-;16?,19?,23-/m00000/s1
InChIKeyZCBMNQJIPLDLEO-SWXHSCONSA-N
MW2273.50 g/mol
LogP26.40
Rot. Bonds26

About N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide

N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide (PubChem CID 162078884) has the molecular formula C125H137F16N11O11 and a molecular weight of 2273.50 g/mol. Its IUPAC name is N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide.

Molecular Properties

Compound NameN-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
PubChem CID162078884
Molecular FormulaC125H137F16N11O11
Molecular Weight2273.50 g/mol
Exact Mass2272.02
IUPAC NameN-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
SMILESCCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2ccc(C(N)=O)nc2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccc(C#N)c2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccnc2C#N)CC1.C[C@H]1C[C@H](c2ccc(C#N)cc2)CC[C@H]1N(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CC1.C[C@](O)(c1ccc(C(=O)N(C2CCC(c3ccccc3F)CC2)C2CC2)cc1)C(F)(F)F
InChIInChI=1S/C27H29F3N2O2.C25H27F4NO2.C25H27F3N2O2.C24H28F3N3O3.C24H26F3N3O2/c1-17-15-21(19-5-3-18(16-31)4-6-19)9-14-24(17)32(23-12-13-23)25(33)20-7-10-22(11-8-20)26(2,34)27(28,29)30;1-24(32,25(27,28)29)18-10-6-17(7-11-18)23(31)30(20-14-15-20)19-12-8-16(9-13-19)21-4-2-3-5-22(21)26;1-3-30(22-13-9-18(10-14-22)20-6-4-5-17(15-20)16-29)23(31)19-7-11-21(12-8-19)24(2,32)25(26,27)28;1-3-30(22(32)16-4-9-18(10-5-16)23(2,33)24(25,26)27)19-11-6-15(7-12-19)17-8-13-20(21(28)31)29-14-17;1-3-30(19-12-8-16(9-13-19)20-5-4-14-29-21(20)15-28)22(31)17-6-10-18(11-7-17)23(2,32)24(25,26)27/h3-8,10-11,17,21,23-24,34H,9,12-15H2,1-2H3;2-7,10-11,16,19-20,32H,8-9,12-15H2,1H3;4-8,11-12,15,18,22,32H,3,9-10,13-14H2,1-2H3;4-5,8-10,13-15,19,33H,3,6-7,11-12H2,1-2H3,(H2,28,31);4-7,10-11,14,16,19,32H,3,8-9,12-13H2,1-2H3/t17-,21+,24+,26-;16?,19?,24-;18?,22?,24-;15?,19?,23-;16?,19?,23-/m00000/s1
InChIKeyZCBMNQJIPLDLEO-SWXHSCONSA-N
XLogP26.40
TPSA342.94 Ų
H-Bond Donors6
H-Bond Acceptors16
Rotatable Bonds26
Heavy Atoms163
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002273.50
LogP ≤ 526.40
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1016

Analyze N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide with MolForge

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Related Compounds

5-[4-[cyclopropyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
CID 57892518
3-[4-[cyclopropyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
CID 57892537
N-[4-(2-cyanopyridin-3-yl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CID 57892544
5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
CID 57892564
3-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide
CID 57892579
N-[4-(6-cyanopyridin-3-yl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CID 57892581
N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]-3-pyridinyl]-6-[2,6-difluoro-4-(1-hydroxycyclopropyl)phenyl]-5-fluoropyridine-2-carboxamide
CID 60172806
N-[4-[(1R,3R,5S)-3-amino-5-methylcyclohexyl]-3-pyridinyl]-6-[2,6-difluoro-4-(1-hydroxycyclopropyl)phenyl]-5-fluoropyridine-2-carboxamide
CID 70655095
[(3R)-3-[4-[2-[2-[2-(2-cyclopropylphenyl)-5-[1-(5-fluoropyridine-2-carbonyl)pyrrolidin-3-yl]-4-(hydroxymethyl)phenyl]cyclopropyl]phenyl]-2-(hydroxymethyl)phenyl]pyrrolidin-1-yl]-(5-fluoro-2-pyridinyl)methanone
CID 156814994
N-[4-(2-cyanophenyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1S,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;bis(N-ethyl-N-(4-pyridin-2-ylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide);N-methyl-N-(4-pyridin-2-ylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CID 157125857
N-[4-(4-cyanophenyl)cyclohexyl]-N-(2-methoxyethyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;bis(N-[4-(2-cyano-4-pyridinyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide);N-[4-(6-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(3-fluoro-4-pyridinyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CID 157255626
N-[4-(4-cyanophenyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-(4-imidazol-1-ylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-(4-phenylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[(1S,3R)-3-pyridin-2-ylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[(1R,3S)-3-pyridin-2-ylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
CID 157261427

Frequently Asked Questions

What is the IUPAC name of N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide?
The IUPAC name of N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide (CID 162078884) is N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide.
What is the SMILES notation for N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide?
The canonical SMILES for N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide is CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2ccc(C(N)=O)nc2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccc(C#N)c2)CC1.CCN(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CCC(c2cccnc2C#N)CC1.C[C@H]1C[C@H](c2ccc(C#N)cc2)CC[C@H]1N(C(=O)c1ccc([C@](C)(O)C(F)(F)F)cc1)C1CC1.C[C@](O)(c1ccc(C(=O)N(C2CCC(c3ccccc3F)CC2)C2CC2)cc1)C(F)(F)F.
What is the InChIKey of N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide?
The InChIKey is ZCBMNQJIPLDLEO-SWXHSCONSA-N. The full InChI is InChI=1S/C27H29F3N2O2.C25H27F4NO2.C25H27F3N2O2.C24H28F3N3O3.C24H26F3N3O2/c1-17-15-21(19-5-3-18(16-31)4-6-19)9-14-24(17)32(23-12-13-23)25(33)20-7-10-22(11-8-20)26(2,34)27(28,29)30;1-24(32,25(27,28)29)18-10-6-17(7-11-18)23(31)30(20-14-15-20)19-12-8-16(9-13-19)21-4-2-3-5-22(21)26;1-3-30(22-13-9-18(10-14-22)20-6-4-5-17(15-20)16-29)23(31)19-7-11-21(12-8-19)24(2,32)25(26,27)28;1-3-30(22(32)16-4-9-18(10-5-16)23(2,33)24(25,26)27)19-11-6-15(7-12-19)17-8-13-20(21(28)31)29-14-17;1-3-30(19-12-8-16(9-13-19)20-5-4-14-29-21(20)15-28)22(31)17-6-10-18(11-7-17)23(2,32)24(25,26)27/h3-8,10-11,17,21,23-24,34H,9,12-15H2,1-2H3;2-7,10-11,16,19-20,32H,8-9,12-15H2,1H3;4-8,11-12,15,18,22,32H,3,9-10,13-14H2,1-2H3;4-5,8-10,13-15,19,33H,3,6-7,11-12H2,1-2H3,(H2,28,31);4-7,10-11,14,16,19,32H,3,8-9,12-13H2,1-2H3/t17-,21+,24+,26-;16?,19?,24-;18?,22?,24-;15?,19?,23-;16?,19?,23-/m00000/s1.
What are the key properties of N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide?
N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide has a molecular weight of 2273.50 g/mol, XLogP of 26.40, 26 rotatable bonds, 6 hydrogen bond donors, and 16 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(3-cyanophenyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[(1R,2S,4R)-4-(4-cyanophenyl)-2-methylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-[4-(2-cyano-3-pyridinyl)cyclohexyl]-N-ethyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;N-cyclopropyl-N-[4-(2-fluorophenyl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide;5-[4-[ethyl-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzoyl]amino]cyclohexyl]pyridine-2-carboxamide is sourced from PubChem (CID 162078884), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).