5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)

C174H191F10N37O10 — CID 162150646

About 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)

5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide) (PubChem CID 162150646) has the molecular formula C174H191F10N37O10 and a molecular weight of 3150.67 g/mol. Its IUPAC name is 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide).

Molecular Properties

• Compound Name: 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)
• PubChem CID: 162150646
• Molecular Formula: C174H191F10N37O10
• Molecular Weight: 3150.67 g/mol
• Exact Mass: 3148.54
• IUPAC Name: 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)
• SMILES: C=C(CN1CCC(c2ccc3ncc(-n4cc(-c5cc(C(=O)NC6CC6)c(F)cc5C)cn4)n3c2)CC1)N(C)C.CCOc1cc2ncc(-n3cnc(-c4cc(C(=O)NC5CC5)c(F)cc4C)c3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cnc(-c4cc(C(=O)NC5CC5)c(F)cc4C)c3)n2cc1C1(F)CCN(C)CC1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc(C4CCN(C5CCC5)CC4)cn23)c1
• InChI: InChI=1S/C31H36FN7O.C30H33FN6O.C29H32F2N6O2.3C28H30F2N6O2/c1-20-13-28(32)27(31(40)35-25-6-7-25)14-26(20)24-15-34-39(19-24)30-16-33-29-8-5-23(18-38(29)30)22-9-11-37(12-10-22)17-21(2)36(3)4;1-19-13-27(31)26(30(38)34-23-6-7-23)14-25(19)22-15-33-37(18-22)29-16-32-28-8-5-21(17-36(28)29)20-9-11-35(12-10-20)24-3-2-4-24;1-4-39-25-13-26-32-14-27(37(26)15-22(25)29(31)7-9-35(3)10-8-29)36-16-24(33-17-36)20-12-21(23(30)11-18(20)2)28(38)34-19-5-6-19;2*1-17-10-23(29)21(27(37)33-19-4-5-19)11-20(17)18-13-32-36(15-18)26-14-31-25-12-24(38-3)22(16-35(25)26)28(30)6-8-34(2)9-7-28;1-17-10-22(29)20(27(37)33-18-4-5-18)11-19(17)23-15-35(16-32-23)26-13-31-25-12-24(38-3)21(14-36(25)26)28(30)6-8-34(2)9-7-28/h5,8,13-16,18-19,22,25H,2,6-7,9-12,17H2,1,3-4H3,(H,35,40);5,8,13-18,20,23-24H,2-4,6-7,9-12H2,1H3,(H,34,38);11-17,19H,4-10H2,1-3H3,(H,34,38);2*10-16,19H,4-9H2,1-3H3,(H,33,37);10-16,18H,4-9H2,1-3H3,(H,33,37)
• InChIKey: ZLDUYSSINAGJPM-UHFFFAOYSA-N
• XLogP: 28.13
• TPSA: 444.92 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 41
• Rotatable Bonds: 39
• Heavy Atoms: 231
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3150.67
LogP ≤ 5	28.13
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)?

The IUPAC name of 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide) (CID 162150646) is 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide).

What is the SMILES notation for 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)?

The canonical SMILES for 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide) is C=C(CN1CCC(c2ccc3ncc(-n4cc(-c5cc(C(=O)NC6CC6)c(F)cc5C)cn4)n3c2)CC1)N(C)C.CCOc1cc2ncc(-n3cnc(-c4cc(C(=O)NC5CC5)c(F)cc4C)c3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1C1(F)CCN(C)CC1.COc1cc2ncc(-n3cnc(-c4cc(C(=O)NC5CC5)c(F)cc4C)c3)n2cc1C1(F)CCN(C)CC1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc(C4CCN(C5CCC5)CC4)cn23)c1.

What is the InChIKey of 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)?

The InChIKey is ZLDUYSSINAGJPM-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H36FN7O.C30H33FN6O.C29H32F2N6O2.3C28H30F2N6O2/c1-20-13-28(32)27(31(40)35-25-6-7-25)14-26(20)24-15-34-39(19-24)30-16-33-29-8-5-23(18-38(29)30)22-9-11-37(12-10-22)17-21(2)36(3)4;1-19-13-27(31)26(30(38)34-23-6-7-23)14-25(19)22-15-33-37(18-22)29-16-32-28-8-5-21(17-36(28)29)20-9-11-35(12-10-20)24-3-2-4-24;1-4-39-25-13-26-32-14-27(37(26)15-22(25)29(31)7-9-35(3)10-8-29)36-16-24(33-17-36)20-12-21(23(30)11-18(20)2)28(38)34-19-5-6-19;2*1-17-10-23(29)21(27(37)33-19-4-5-19)11-20(17)18-13-32-36(15-18)26-14-31-25-12-24(38-3)22(16-35(25)26)28(30)6-8-34(2)9-7-28;1-17-10-22(29)20(27(37)33-18-4-5-18)11-19(17)23-15-35(16-32-23)26-13-31-25-12-24(38-3)21(14-36(25)26)28(30)6-8-34(2)9-7-28/h5,8,13-16,18-19,22,25H,2,6-7,9-12,17H2,1,3-4H3,(H,35,40);5,8,13-18,20,23-24H,2-4,6-7,9-12H2,1H3,(H,34,38);11-17,19H,4-10H2,1-3H3,(H,34,38);2*10-16,19H,4-9H2,1-3H3,(H,33,37);10-16,18H,4-9H2,1-3H3,(H,33,37).

What are the key properties of 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide)?

5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide) has a molecular weight of 3150.67 g/mol, XLogP of 28.13, 39 rotatable bonds, 6 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[1-[6-(1-cyclobutylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-N-cyclopropyl-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[6-[1-[2-(dimethylamino)prop-2-enyl]piperidin-4-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoro-1-methylpiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]imidazol-4-yl]-4-methylbenzamide;bis(N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoro-1-methylpiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide) is sourced from PubChem (CID 162150646), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).