4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

C69H67F3N16O5 — CID 162159416

About 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine

4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 162159416) has the molecular formula C69H67F3N16O5 and a molecular weight of 1257.40 g/mol. Its IUPAC name is 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 162159416
• Molecular Formula: C69H67F3N16O5
• Molecular Weight: 1257.40 g/mol
• Exact Mass: 1256.54
• IUPAC Name: 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine
• SMILES: Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)ccn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(=O)N(C)C)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cnn(CC(C)O)c3)c2n1
• InChI: InChI=1S/C25H24FN5O2.C22H23FN6O2.C22H20FN5O/c1-15-14-31-23(29-15)19(16-4-6-17(7-5-16)24(32)30(2)3)12-27-25(31)28-13-20-18-10-11-33-22(18)9-8-21(20)26;1-13-10-29-21(27-13)17(15-7-26-28(12-15)11-14(2)30)8-24-22(29)25-9-18-16-5-6-31-20(16)4-3-19(18)23;1-13-9-15(5-7-24-13)17-10-25-22(28-12-14(2)27-21(17)28)26-11-18-16-6-8-29-20(16)4-3-19(18)23/h4-9,12,14H,10-11,13H2,1-3H3,(H,27,28);3-4,7-8,10,12,14,30H,5-6,9,11H2,1-2H3,(H,24,25);3-5,7,9-10,12H,6,8,11H2,1-2H3,(H,25,26)
• InChIKey: ZMGTVGMWWOGKDB-UHFFFAOYSA-N
• XLogP: 11.15
• TPSA: 225.60 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 20
• Rotatable Bonds: 15
• Heavy Atoms: 93
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1257.40
LogP ≤ 5	11.15
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine (CID 162159416) is 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is Cc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)ccn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(=O)N(C)C)cc3)c2n1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3cnn(CC(C)O)c3)c2n1.

What is the InChIKey of 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is ZMGTVGMWWOGKDB-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H24FN5O2.C22H23FN6O2.C22H20FN5O/c1-15-14-31-23(29-15)19(16-4-6-17(7-5-16)24(32)30(2)3)12-27-25(31)28-13-20-18-10-11-33-22(18)9-8-21(20)26;1-13-10-29-21(27-13)17(15-7-26-28(12-15)11-14(2)30)8-24-22(29)25-9-18-16-5-6-31-20(16)4-3-19(18)23;1-13-9-15(5-7-24-13)17-10-25-22(28-12-14(2)27-21(17)28)26-11-18-16-6-8-29-20(16)4-3-19(18)23/h4-9,12,14H,10-11,13H2,1-3H3,(H,27,28);3-4,7-8,10,12,14,30H,5-6,9,11H2,1-2H3,(H,24,25);3-5,7,9-10,12H,6,8,11H2,1-2H3,(H,25,26).

What are the key properties of 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine?

4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1257.40 g/mol, XLogP of 11.15, 15 rotatable bonds, 4 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]-N,N-dimethylbenzamide;1-[4-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-2-methylimidazo[1,2-c]pyrimidin-8-yl]pyrazol-1-yl]propan-2-ol;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-(2-methyl-4-pyridinyl)imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 162159416), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).