3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate

C144H140Br2F4N26O10S6 — CID 162169722

About 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate

3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate (PubChem CID 162169722) has the molecular formula C144H140Br2F4N26O10S6 and a molecular weight of 2823.08 g/mol. Its IUPAC name is 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate.

Molecular Properties

• Compound Name: 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate
• PubChem CID: 162169722
• Molecular Formula: C144H140Br2F4N26O10S6
• Molecular Weight: 2823.08 g/mol
• Exact Mass: 2818.79
• IUPAC Name: 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate
• SMILES: CCN1CCc2nc3oc(C(=O)Nc4c(F)cc(F)cc4Br)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccc5ccccc5c4)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccccc4-c4ccccc4)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccccc4C)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Oc4c(F)cc(F)cc4Br)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Oc4ccccc4C)c(N)c3cc2C1.Cc1ccccc1NC(=O)c1sc2nc3c(cc2c1N)CNCC3
• InChI: InChI=1S/C25H24N4OS.C23H22N4OS.C20H22N4OS.C20H21N3O2S.C19H17BrF2N4O2.C19H16BrF2N3O2S.C18H18N4OS/c1-2-29-13-12-20-17(15-29)14-19-22(26)23(31-25(19)28-20)24(30)27-21-11-7-6-10-18(21)16-8-4-3-5-9-16;1-2-27-10-9-19-16(13-27)12-18-20(24)21(29-23(18)26-19)22(28)25-17-8-7-14-5-3-4-6-15(14)11-17;1-3-24-9-8-16-13(11-24)10-14-17(21)18(26-20(14)23-16)19(25)22-15-7-5-4-6-12(15)2;1-3-23-9-8-15-13(11-23)10-14-17(21)18(26-19(14)22-15)20(24)25-16-7-5-4-6-12(16)2;1-2-26-4-3-14-9(8-26)5-11-15(23)17(28-19(11)24-14)18(27)25-16-12(20)6-10(21)7-13(16)22;1-2-25-4-3-14-9(8-25)5-11-15(23)17(28-18(11)24-14)19(26)27-16-12(20)6-10(21)7-13(16)22;1-10-4-2-3-5-13(10)21-17(23)16-15(19)12-8-11-9-20-7-6-14(11)22-18(12)24-16/h3-11,14H,2,12-13,15,26H2,1H3,(H,27,30);3-8,11-12H,2,9-10,13,24H2,1H3,(H,25,28);4-7,10H,3,8-9,11,21H2,1-2H3,(H,22,25);4-7,10H,3,8-9,11,21H2,1-2H3;5-7H,2-4,8,23H2,1H3,(H,25,27);5-7H,2-4,8,23H2,1H3;2-5,8,20H,6-7,9,19H2,1H3,(H,21,23)
• InChIKey: ZNPVOAREQAKFCW-UHFFFAOYSA-N
• XLogP: 29.12
• TPSA: 515.08 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 37
• Rotatable Bonds: 21
• Heavy Atoms: 192
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2823.08
LogP ≤ 5	29.12
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phenol_ester', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate?

The IUPAC name of 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate (CID 162169722) is 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate.

What is the SMILES notation for 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate?

The canonical SMILES for 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate is CCN1CCc2nc3oc(C(=O)Nc4c(F)cc(F)cc4Br)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccc5ccccc5c4)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccccc4-c4ccccc4)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Nc4ccccc4C)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Oc4c(F)cc(F)cc4Br)c(N)c3cc2C1.CCN1CCc2nc3sc(C(=O)Oc4ccccc4C)c(N)c3cc2C1.Cc1ccccc1NC(=O)c1sc2nc3c(cc2c1N)CNCC3.

What is the InChIKey of 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate?

The InChIKey is ZNPVOAREQAKFCW-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H24N4OS.C23H22N4OS.C20H22N4OS.C20H21N3O2S.C19H17BrF2N4O2.C19H16BrF2N3O2S.C18H18N4OS/c1-2-29-13-12-20-17(15-29)14-19-22(26)23(31-25(19)28-20)24(30)27-21-11-7-6-10-18(21)16-8-4-3-5-9-16;1-2-27-10-9-19-16(13-27)12-18-20(24)21(29-23(18)26-19)22(28)25-17-8-7-14-5-3-4-6-15(14)11-17;1-3-24-9-8-16-13(11-24)10-14-17(21)18(26-20(14)23-16)19(25)22-15-7-5-4-6-12(15)2;1-3-23-9-8-15-13(11-23)10-14-17(21)18(26-19(14)22-15)20(24)25-16-7-5-4-6-12(16)2;1-2-26-4-3-14-9(8-26)5-11-15(23)17(28-19(11)24-14)18(27)25-16-12(20)6-10(21)7-13(16)22;1-2-25-4-3-14-9(8-25)5-11-15(23)17(28-18(11)24-14)19(26)27-16-12(20)6-10(21)7-13(16)22;1-10-4-2-3-5-13(10)21-17(23)16-15(19)12-8-11-9-20-7-6-14(11)22-18(12)24-16/h3-11,14H,2,12-13,15,26H2,1H3,(H,27,30);3-8,11-12H,2,9-10,13,24H2,1H3,(H,25,28);4-7,10H,3,8-9,11,21H2,1-2H3,(H,22,25);4-7,10H,3,8-9,11,21H2,1-2H3;5-7H,2-4,8,23H2,1H3,(H,25,27);5-7H,2-4,8,23H2,1H3;2-5,8,20H,6-7,9,19H2,1H3,(H,21,23).

What are the key properties of 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate?

3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate has a molecular weight of 2823.08 g/mol, XLogP of 29.12, 21 rotatable bonds, 13 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 3-amino-N-(2-bromo-4,6-difluorophenyl)-6-ethyl-7,8-dihydro-5H-furo[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-methylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-naphthalen-2-yl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-6-ethyl-N-(2-phenylphenyl)-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxamide;3-amino-N-(2-methylphenyl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide;(2-bromo-4,6-difluorophenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate;(2-methylphenyl) 3-amino-6-ethyl-7,8-dihydro-5H-thieno[2,3-b][1,6]naphthyridine-2-carboxylate is sourced from PubChem (CID 162169722), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).