N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

C105H125F2N19O15S4 — CID 162172275

About N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide (PubChem CID 162172275) has the molecular formula C105H125F2N19O15S4 and a molecular weight of 2059.54 g/mol. Its IUPAC name is N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
• PubChem CID: 162172275
• Molecular Formula: C105H125F2N19O15S4
• Molecular Weight: 2059.54 g/mol
• Exact Mass: 2057.85
• IUPAC Name: N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
• SMILES: CC1CN(c2nc(OC(C)C(C)C)c(F)cc2C(=O)NS(=O)(=O)c2cccc(N)n2)C(C)(C)C1.CC1CN(c2ncc(-c3ccc(C(C)C)cc3)cc2C(=O)NS(=O)(=O)c2cccc(N)n2)C(C)(C)C1.CCOc1cc(F)ccc1-c1ccc(C(=O)NS(=O)(=O)c2cccnc2N)c(N2C[C@@H](C)CC2(C)C)n1.Cc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3ccc[nH]c3=O)c(N3C[C@@H](C)CC3(C)C)n2)c2ccccc12
• InChI: InChI=1S/C29H30N4O4S.C27H33N5O3S.C26H30FN5O4S.C23H32FN5O4S/c1-18-16-29(3,4)33(17-18)26-23(27(34)32-38(36,37)25-10-7-15-30-28(25)35)13-14-24(31-26)22-12-11-19(2)20-8-5-6-9-21(20)22;1-17(2)19-9-11-20(12-10-19)21-13-22(25(29-15-21)32-16-18(3)14-27(32,4)5)26(33)31-36(34,35)24-8-6-7-23(28)30-24;1-5-36-21-13-17(27)8-9-18(21)20-11-10-19(24(30-20)32-15-16(2)14-26(32,3)4)25(33)31-37(34,35)22-7-6-12-29-23(22)28;1-13(2)15(4)33-22-17(24)10-16(20(27-22)29-12-14(3)11-23(29,5)6)21(30)28-34(31,32)19-9-7-8-18(25)26-19/h5-15,18H,16-17H2,1-4H3,(H,30,35)(H,32,34);6-13,15,17-18H,14,16H2,1-5H3,(H2,28,30)(H,31,33);6-13,16H,5,14-15H2,1-4H3,(H2,28,29)(H,31,33);7-10,13-15H,11-12H2,1-6H3,(H2,25,26)(H,28,30)/t18-;;16-;/m0.0./s1
• InChIKey: ZNYHAUKWXKEKHQ-OONNBDSJSA-N
• XLogP: 16.61
• TPSA: 485.53 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 29
• Rotatable Bonds: 25
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2059.54
LogP ≤ 5	16.61
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The IUPAC name of N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide (CID 162172275) is N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide.

What is the SMILES notation for N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The canonical SMILES for N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide is CC1CN(c2nc(OC(C)C(C)C)c(F)cc2C(=O)NS(=O)(=O)c2cccc(N)n2)C(C)(C)C1.CC1CN(c2ncc(-c3ccc(C(C)C)cc3)cc2C(=O)NS(=O)(=O)c2cccc(N)n2)C(C)(C)C1.CCOc1cc(F)ccc1-c1ccc(C(=O)NS(=O)(=O)c2cccnc2N)c(N2C[C@@H](C)CC2(C)C)n1.Cc1ccc(-c2ccc(C(=O)NS(=O)(=O)c3ccc[nH]c3=O)c(N3C[C@@H](C)CC3(C)C)n2)c2ccccc12.

What is the InChIKey of N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

The InChIKey is ZNYHAUKWXKEKHQ-OONNBDSJSA-N. The full InChI is InChI=1S/C29H30N4O4S.C27H33N5O3S.C26H30FN5O4S.C23H32FN5O4S/c1-18-16-29(3,4)33(17-18)26-23(27(34)32-38(36,37)25-10-7-15-30-28(25)35)13-14-24(31-26)22-12-11-19(2)20-8-5-6-9-21(20)22;1-17(2)19-9-11-20(12-10-19)21-13-22(25(29-15-21)32-16-18(3)14-27(32,4)5)26(33)31-36(34,35)24-8-6-7-23(28)30-24;1-5-36-21-13-17(27)8-9-18(21)20-11-10-19(24(30-20)32-15-16(2)14-26(32,3)4)25(33)31-37(34,35)22-7-6-12-29-23(22)28;1-13(2)15(4)33-22-17(24)10-16(20(27-22)29-12-14(3)11-23(29,5)6)21(30)28-34(31,32)19-9-7-8-18(25)26-19/h5-15,18H,16-17H2,1-4H3,(H,30,35)(H,32,34);6-13,15,17-18H,14,16H2,1-5H3,(H2,28,30)(H,31,33);6-13,16H,5,14-15H2,1-4H3,(H2,28,29)(H,31,33);7-10,13-15H,11-12H2,1-6H3,(H2,25,26)(H,28,30)/t18-;;16-;/m0.0./s1.

What are the key properties of N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide?

N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide has a molecular weight of 2059.54 g/mol, XLogP of 16.61, 25 rotatable bonds, 8 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(2-amino-3-pyridinyl)sulfonyl]-6-(2-ethoxy-4-fluorophenyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-fluoro-6-(3-methylbutan-2-yloxy)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;N-[(6-amino-2-pyridinyl)sulfonyl]-5-(4-propan-2-ylphenyl)-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide;6-(4-methylnaphthalen-1-yl)-N-[(2-oxo-1H-pyridin-3-yl)sulfonyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide is sourced from PubChem (CID 162172275), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).