(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide

C99H131Cl5N16O17 — CID 162186101

About (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide

(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide (PubChem CID 162186101) has the molecular formula C99H131Cl5N16O17 and a molecular weight of 1994.50 g/mol. Its IUPAC name is (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide.

Molecular Properties

• Compound Name: (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide
• PubChem CID: 162186101
• Molecular Formula: C99H131Cl5N16O17
• Molecular Weight: 1994.50 g/mol
• Exact Mass: 1990.83
• IUPAC Name: (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide
• SMILES: COCC(COC)n1nccc1[C@@H](Cc1ccc(Cl)cc1)[C@@H](CC(=O)NO)OC.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCCCC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCN(C)CC1
• InChI: InChI=1S/C21H29ClN4O3.C21H28ClN3O3.C20H28ClN3O5.C19H24ClN3O3.C18H22ClN3O3/c1-25-11-8-17(9-12-25)26-19(7-10-23-26)18(20(29-2)14-21(27)24-28)13-15-3-5-16(22)6-4-15;1-28-20(14-21(26)24-27)18(13-15-7-9-16(22)10-8-15)19-11-12-23-25(19)17-5-3-2-4-6-17;1-27-12-16(13-28-2)24-18(8-9-22-24)17(19(29-3)11-20(25)23-26)10-14-4-6-15(21)7-5-14;1-26-18(12-19(24)22-25)16(11-13-5-7-14(20)8-6-13)17-9-10-21-23(17)15-3-2-4-15;1-25-17(11-18(23)21-24)15(10-12-2-4-13(19)5-3-12)16-8-9-20-22(16)14-6-7-14/h3-7,10,17-18,20,28H,8-9,11-14H2,1-2H3,(H,24,27);7-12,17-18,20,27H,2-6,13-14H2,1H3,(H,24,26);4-9,16-17,19,26H,10-13H2,1-3H3,(H,23,25);5-10,15-16,18,25H,2-4,11-12H2,1H3,(H,22,24);2-5,8-9,14-15,17,24H,6-7,10-11H2,1H3,(H,21,23)/t2*18-,20-;17-,19-;16-,18-;15-,17-/m11111/s1
• InChIKey: ZPRDFZQCGPNCQA-RBVWZFGUSA-N
• XLogP: 16.53
• TPSA: 403.60 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 28
• Rotatable Bonds: 44
• Heavy Atoms: 137
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1994.50
LogP ≤ 5	16.53
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide?

The IUPAC name of (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide (CID 162186101) is (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide.

What is the SMILES notation for (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide?

The canonical SMILES for (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide is COCC(COC)n1nccc1[C@@H](Cc1ccc(Cl)cc1)[C@@H](CC(=O)NO)OC.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCCCC1.CO[C@H](CC(=O)NO)[C@H](Cc1ccc(Cl)cc1)c1ccnn1C1CCN(C)CC1.

What is the InChIKey of (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide?

The InChIKey is ZPRDFZQCGPNCQA-RBVWZFGUSA-N. The full InChI is InChI=1S/C21H29ClN4O3.C21H28ClN3O3.C20H28ClN3O5.C19H24ClN3O3.C18H22ClN3O3/c1-25-11-8-17(9-12-25)26-19(7-10-23-26)18(20(29-2)14-21(27)24-28)13-15-3-5-16(22)6-4-15;1-28-20(14-21(26)24-27)18(13-15-7-9-16(22)10-8-15)19-11-12-23-25(19)17-5-3-2-4-6-17;1-27-12-16(13-28-2)24-18(8-9-22-24)17(19(29-3)11-20(25)23-26)10-14-4-6-15(21)7-5-14;1-26-18(12-19(24)22-25)16(11-13-5-7-14(20)8-6-13)17-9-10-21-23(17)15-3-2-4-15;1-25-17(11-18(23)21-24)15(10-12-2-4-13(19)5-3-12)16-8-9-20-22(16)14-6-7-14/h3-7,10,17-18,20,28H,8-9,11-14H2,1-2H3,(H,24,27);7-12,17-18,20,27H,2-6,13-14H2,1H3,(H,24,26);4-9,16-17,19,26H,10-13H2,1-3H3,(H,23,25);5-10,15-16,18,25H,2-4,11-12H2,1H3,(H,22,24);2-5,8-9,14-15,17,24H,6-7,10-11H2,1H3,(H,21,23)/t2*18-,20-;17-,19-;16-,18-;15-,17-/m11111/s1.

What are the key properties of (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide?

(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide has a molecular weight of 1994.50 g/mol, XLogP of 16.53, 44 rotatable bonds, 10 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for (3R,4R)-5-(4-chlorophenyl)-4-(2-cyclobutylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclohexylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-(2-cyclopropylpyrazol-3-yl)-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-4-[2-(1,3-dimethoxypropan-2-yl)pyrazol-3-yl]-N-hydroxy-3-methoxypentanamide;(3R,4R)-5-(4-chlorophenyl)-N-hydroxy-3-methoxy-4-[2-(1-methylpiperidin-4-yl)pyrazol-3-yl]pentanamide is sourced from PubChem (CID 162186101), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).