1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one

C118H100F12N20O8 — CID 162189969

About 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one

1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one (PubChem CID 162189969) has the molecular formula C118H100F12N20O8 and a molecular weight of 2154.21 g/mol. Its IUPAC name is 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one.

Molecular Properties

• Compound Name: 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one
• PubChem CID: 162189969
• Molecular Formula: C118H100F12N20O8
• Molecular Weight: 2154.21 g/mol
• Exact Mass: 2152.78
• IUPAC Name: 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one
• SMILES: O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)cc2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)cc2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2cccc(C(F)(F)F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2cccc(C(F)(F)F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1
• InChI: InChI=1S/2C30H26F3N5O2.2C29H24F3N5O2/c31-30(32,33)22-5-4-8-24(19-22)38-26(21-9-14-34-15-10-21)20-25(35-38)28(40)36-17-12-29(13-18-36)27(39)11-16-37(29)23-6-2-1-3-7-23;31-30(32,33)22-6-8-24(9-7-22)38-26(21-10-15-34-16-11-21)20-25(35-38)28(40)36-18-13-29(14-19-36)27(39)12-17-37(29)23-4-2-1-3-5-23;30-29(31,32)21-5-3-6-23(17-21)37-26(19-8-12-33-13-9-19)18-24(34-37)28(39)35-14-10-22(11-15-35)36-25-7-2-1-4-20(25)16-27(36)38;30-29(31,32)21-5-7-23(8-6-21)37-26(19-9-13-33-14-10-19)18-24(34-37)28(39)35-15-11-22(12-16-35)36-25-4-2-1-3-20(25)17-27(36)38/h1-10,14-15,19-20H,11-13,16-18H2;1-11,15-16,20H,12-14,17-19H2;1-9,12-13,17-18,22H,10-11,14-16H2;1-10,13-14,18,22H,11-12,15-17H2
• InChIKey: ZQDYTAVYQJNHMB-UHFFFAOYSA-N
• XLogP: 21.11
• TPSA: 285.32 Ų
• H-Bond Acceptors: 22
• Rotatable Bonds: 16
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2154.21
LogP ≤ 5	21.11
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	22

Frequently Asked Questions

What is the IUPAC name of 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The IUPAC name of 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one (CID 162189969) is 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one.

What is the SMILES notation for 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The canonical SMILES for 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one is O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)cc2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)cc2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2cccc(C(F)(F)F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2cccc(C(F)(F)F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.

What is the InChIKey of 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The InChIKey is ZQDYTAVYQJNHMB-UHFFFAOYSA-N. The full InChI is InChI=1S/2C30H26F3N5O2.2C29H24F3N5O2/c31-30(32,33)22-5-4-8-24(19-22)38-26(21-9-14-34-15-10-21)20-25(35-38)28(40)36-17-12-29(13-18-36)27(39)11-16-37(29)23-6-2-1-3-7-23;31-30(32,33)22-6-8-24(9-7-22)38-26(21-10-15-34-16-11-21)20-25(35-38)28(40)36-18-13-29(14-19-36)27(39)12-17-37(29)23-4-2-1-3-5-23;30-29(31,32)21-5-3-6-23(17-21)37-26(19-8-12-33-13-9-19)18-24(34-37)28(39)35-14-10-22(11-15-35)36-25-7-2-1-4-20(25)16-27(36)38;30-29(31,32)21-5-7-23(8-6-21)37-26(19-9-13-33-14-10-19)18-24(34-37)28(39)35-15-11-22(12-16-35)36-25-4-2-1-3-20(25)17-27(36)38/h1-10,14-15,19-20H,11-13,16-18H2;1-11,15-16,20H,12-14,17-19H2;1-9,12-13,17-18,22H,10-11,14-16H2;1-10,13-14,18,22H,11-12,15-17H2.

What are the key properties of 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one has a molecular weight of 2154.21 g/mol, XLogP of 21.11, 16 rotatable bonds, 0 hydrogen bond donors, and 22 hydrogen bond acceptors.

Where does this data come from?

All data for 1-phenyl-8-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-phenyl-8-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-[1-[5-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;1-[1-[5-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one is sourced from PubChem (CID 162189969), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).