1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol

C104H110Cl6F18N20O10 — CID 162195654

About 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol

1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol (PubChem CID 162195654) has the molecular formula C104H110Cl6F18N20O10 and a molecular weight of 2354.84 g/mol. Its IUPAC name is 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol.

Molecular Properties

• Compound Name: 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol
• PubChem CID: 162195654
• Molecular Formula: C104H110Cl6F18N20O10
• Molecular Weight: 2354.84 g/mol
• Exact Mass: 2350.66
• IUPAC Name: 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol
• SMILES: CC(=O)N1CCC(C(F)(F)C(O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.N#CCCCNC(=O)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.O=C(NC1CCC(F)(F)CC1)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.O=C(NCCCF)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.OC(c1cc(Cl)cc2cn[nH]c12)C1(C(F)(F)F)CCCC1.OC1(c2cc(Cl)cc3cn[nH]c23)CC2(CCCCC2)C1
• InChI: InChI=1S/C21H22ClF5N4O2.C19H19ClF3N5O2.C18H19ClF4N4O2.C16H17ClF3N3O2.C16H19ClN2O.C14H14ClF3N2O/c22-14-9-11-10-28-30-17(11)15(16(14)23)18(32)21(26,27)12-3-7-31(8-4-12)19(33)29-13-1-5-20(24,25)6-2-13;20-13-9-11-10-26-27-16(11)14(15(13)21)17(29)19(22,23)12-3-7-28(8-4-12)18(30)25-6-2-1-5-24;19-12-8-10-9-25-26-15(10)13(14(12)21)16(28)18(22,23)11-2-6-27(7-3-11)17(29)24-5-1-4-20;1-8(24)23-4-2-10(3-5-23)16(19,20)15(25)12-13(18)11(17)6-9-7-21-22-14(9)12;17-12-6-11-8-18-19-14(11)13(7-12)16(20)9-15(10-16)4-2-1-3-5-15;15-9-5-8-7-19-20-11(8)10(6-9)12(21)13(14(16,17)18)3-1-2-4-13/h9-10,12-13H,1-8H2,(H,28,30)(H,29,33);9-10,12H,1-4,6-8H2,(H,25,30)(H,26,27);8-9,11H,1-7H2,(H,24,29)(H,25,26);6-7,10,15,25H,2-5H2,1H3,(H,21,22);6-8,20H,1-5,9-10H2,(H,18,19);5-7,12,21H,1-4H2,(H,19,20)
• InChIKey: ZQXAMIKSLQPCGI-UHFFFAOYSA-N
• XLogP: 24.83
• TPSA: 425.10 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 17
• Rotatable Bonds: 22
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2354.84
LogP ≤ 5	24.83
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	17

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol?

The IUPAC name of 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol (CID 162195654) is 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol.

What is the SMILES notation for 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol?

The canonical SMILES for 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol is CC(=O)N1CCC(C(F)(F)C(O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.N#CCCCNC(=O)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.O=C(NC1CCC(F)(F)CC1)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.O=C(NCCCF)N1CCC(C(F)(F)C(=O)c2c(F)c(Cl)cc3cn[nH]c23)CC1.OC(c1cc(Cl)cc2cn[nH]c12)C1(C(F)(F)F)CCCC1.OC1(c2cc(Cl)cc3cn[nH]c23)CC2(CCCCC2)C1.

What is the InChIKey of 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol?

The InChIKey is ZQXAMIKSLQPCGI-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H22ClF5N4O2.C19H19ClF3N5O2.C18H19ClF4N4O2.C16H17ClF3N3O2.C16H19ClN2O.C14H14ClF3N2O/c22-14-9-11-10-28-30-17(11)15(16(14)23)18(32)21(26,27)12-3-7-31(8-4-12)19(33)29-13-1-5-20(24,25)6-2-13;20-13-9-11-10-26-27-16(11)14(15(13)21)17(29)19(22,23)12-3-7-28(8-4-12)18(30)25-6-2-1-5-24;19-12-8-10-9-25-26-15(10)13(14(12)21)16(28)18(22,23)11-2-6-27(7-3-11)17(29)24-5-1-4-20;1-8(24)23-4-2-10(3-5-23)16(19,20)15(25)12-13(18)11(17)6-9-7-21-22-14(9)12;17-12-6-11-8-18-19-14(11)13(7-12)16(20)9-15(10-16)4-2-1-3-5-15;15-9-5-8-7-19-20-11(8)10(6-9)12(21)13(14(16,17)18)3-1-2-4-13/h9-10,12-13H,1-8H2,(H,28,30)(H,29,33);9-10,12H,1-4,6-8H2,(H,25,30)(H,26,27);8-9,11H,1-7H2,(H,24,29)(H,25,26);6-7,10,15,25H,2-5H2,1H3,(H,21,22);6-8,20H,1-5,9-10H2,(H,18,19);5-7,12,21H,1-4H2,(H,19,20).

What are the key properties of 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol?

1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol has a molecular weight of 2354.84 g/mol, XLogP of 24.83, 22 rotatable bonds, 12 hydrogen bond donors, and 17 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-hydroxyethyl]piperidin-1-yl]ethanone;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-cyanopropyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(4,4-difluorocyclohexyl)piperidine-1-carboxamide;4-[2-(5-chloro-6-fluoro-1H-indazol-7-yl)-1,1-difluoro-2-oxoethyl]-N-(3-fluoropropyl)piperidine-1-carboxamide;2-(5-chloro-1H-indazol-7-yl)spiro[3.5]nonan-2-ol;(5-chloro-1H-indazol-7-yl)-[1-(trifluoromethyl)cyclopentyl]methanol is sourced from PubChem (CID 162195654), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).