(5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione

C112H101N19O16S — CID 162199144

About (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione

(5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione (PubChem CID 162199144) has the molecular formula C112H101N19O16S and a molecular weight of 2001.22 g/mol. Its IUPAC name is (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione.

Molecular Properties

• Compound Name: (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione
• PubChem CID: 162199144
• Molecular Formula: C112H101N19O16S
• Molecular Weight: 2001.22 g/mol
• Exact Mass: 1999.74
• IUPAC Name: (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione
• SMILES: COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4cc(C)c5nn(C(C)C)cc5c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4ccc5c(cnn5CC5CC5)c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4ccc5nn(CC6CC6)cc5c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4nccs4)cc3)NC(=O)NC1=O)C2
• InChI: InChI=1S/2C30H27N5O4.C30H29N5O4.C22H18N4O4S/c1-39-24-10-6-21-16-34(27(36)25(21)13-24)17-30(28(37)32-29(38)33-30)23-8-4-19(5-9-23)20-7-11-26-22(12-20)14-31-35(26)15-18-2-3-18;1-39-24-10-6-21-15-34(27(36)25(21)13-24)17-30(28(37)31-29(38)32-30)23-8-4-19(5-9-23)20-7-11-26-22(12-20)16-35(33-26)14-18-2-3-18;1-17(2)35-15-22-12-21(11-18(3)26(22)33-35)19-5-8-23(9-6-19)30(28(37)31-29(38)32-30)16-34-14-20-7-10-24(39-4)13-25(20)27(34)36;1-30-16-7-4-14-11-26(19(27)17(14)10-16)12-22(20(28)24-21(29)25-22)15-5-2-13(3-6-15)18-23-8-9-31-18/h4-14,18H,2-3,15-17H2,1H3,(H2,32,33,37,38);4-13,16,18H,2-3,14-15,17H2,1H3,(H2,31,32,37,38);5-13,15,17H,14,16H2,1-4H3,(H2,31,32,37,38);2-10H,11-12H2,1H3,(H2,24,25,28,29)/t3*30-;22-/m0000/s1
• InChIKey: ZRIQFMZRCBEKNW-SCOJMYOSSA-N
• XLogP: 14.43
• TPSA: 417.31 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 24
• Rotatable Bonds: 25
• Heavy Atoms: 148
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2001.22
LogP ≤ 5	14.43
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	24

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione?

The IUPAC name of (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione (CID 162199144) is (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione.

What is the SMILES notation for (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione?

The canonical SMILES for (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione is COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4cc(C)c5nn(C(C)C)cc5c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4ccc5c(cnn5CC5CC5)c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4ccc5nn(CC6CC6)cc5c4)cc3)NC(=O)NC1=O)C2.COc1ccc2c(c1)C(=O)N(C[C@@]1(c3ccc(-c4nccs4)cc3)NC(=O)NC1=O)C2.

What is the InChIKey of (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione?

The InChIKey is ZRIQFMZRCBEKNW-SCOJMYOSSA-N. The full InChI is InChI=1S/2C30H27N5O4.C30H29N5O4.C22H18N4O4S/c1-39-24-10-6-21-16-34(27(36)25(21)13-24)17-30(28(37)32-29(38)33-30)23-8-4-19(5-9-23)20-7-11-26-22(12-20)14-31-35(26)15-18-2-3-18;1-39-24-10-6-21-15-34(27(36)25(21)13-24)17-30(28(37)31-29(38)32-30)23-8-4-19(5-9-23)20-7-11-26-22(12-20)16-35(33-26)14-18-2-3-18;1-17(2)35-15-22-12-21(11-18(3)26(22)33-35)19-5-8-23(9-6-19)30(28(37)31-29(38)32-30)16-34-14-20-7-10-24(39-4)13-25(20)27(34)36;1-30-16-7-4-14-11-26(19(27)17(14)10-16)12-22(20(28)24-21(29)25-22)15-5-2-13(3-6-15)18-23-8-9-31-18/h4-14,18H,2-3,15-17H2,1H3,(H2,32,33,37,38);4-13,16,18H,2-3,14-15,17H2,1H3,(H2,31,32,37,38);5-13,15,17H,14,16H2,1-4H3,(H2,31,32,37,38);2-10H,11-12H2,1H3,(H2,24,25,28,29)/t3*30-;22-/m0000/s1.

What are the key properties of (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione?

(5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione has a molecular weight of 2001.22 g/mol, XLogP of 14.43, 25 rotatable bonds, 8 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-5-[4-[1-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[4-[2-(cyclopropylmethyl)indazol-5-yl]phenyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(7-methyl-2-propan-2-ylindazol-5-yl)phenyl]imidazolidine-2,4-dione;(5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(1,3-thiazol-2-yl)phenyl]imidazolidine-2,4-dione is sourced from PubChem (CID 162199144), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).