4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide

C154H190F9N27O26S13 — CID 162202163

IUPAC4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide
SMILESCC(C)(C1CCN(C(=O)Nc2ccns2)CC1)S(=O)(=O)c1cc(F)cc(F)c1.CC(C)(C1CCN(C(=O)Nc2cnns2)CC1)S(=O)(=O)c1cccc(F)c1.CC(F)(F)Oc1ccc(S(=O)(=O)C2(C3CCN(C(=O)Nc4ccns4)CC3)CC2)cc1.COc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1cc(NC(=O)N2CCC([C@](C)(F)S(=O)(=O)c3cc(C(C)(F)F)nn3C)CC2)ccn1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccns2)CC1.O=C(Nc1ccns1)N1CCC(C2(S(=O)(=O)c3cccc(F)c3)CC2)CC1
InChIInChI=1S/C21H27N3O4S.C21H27N3O3S.C20H26F3N5O3S.C20H23F2N3O4S2.C19H25N3O3S2.C18H21F2N3O3S2.C18H20FN3O3S2.C17H21FN4O3S2/c1-21(2,29(26,27)19-7-5-4-6-18(19)28-3)16-10-14-24(15-11-16)20(25)23-17-8-12-22-13-9-17;1-16-6-4-5-7-19(16)28(26,27)21(2,3)17-10-14-24(15-11-17)20(25)23-18-8-12-22-13-9-18;1-13-11-15(5-8-24-13)25-18(29)28-9-6-14(7-10-28)20(3,23)32(30,31)17-12-16(19(2,21)22)26-27(17)4;1-19(21,22)29-15-2-4-16(5-3-15)31(27,28)20(9-10-20)14-7-12-25(13-8-14)18(26)24-17-6-11-23-30-17;1-14-6-4-5-7-16(14)27(24,25)19(2,3)15-9-12-22(13-10-15)18(23)21-17-8-11-20-26-17;1-18(2,28(25,26)15-10-13(19)9-14(20)11-15)12-4-7-23(8-5-12)17(24)22-16-3-6-21-27-16;19-14-2-1-3-15(12-14)27(24,25)18(7-8-18)13-5-10-22(11-6-13)17(23)21-16-4-9-20-26-16;1-17(2,27(24,25)14-5-3-4-13(18)10-14)12-6-8-22(9-7-12)16(23)20-15-11-19-21-26-15/h4-9,12-13,16H,10-11,14-15H2,1-3H3,(H,22,23,25);4-9,12-13,17H,10-11,14-15H2,1-3H3,(H,22,23,25);5,8,11-12,14H,6-7,9-10H2,1-4H3,(H,24,25,29);2-6,11,14H,7-10,12-13H2,1H3,(H,24,26);4-8,11,15H,9-10,12-13H2,1-3H3,(H,21,23);3,6,9-12H,4-5,7-8H2,1-2H3,(H,22,24);1-4,9,12-13H,5-8,10-11H2,(H,21,23);3-5,10-12H,6-9H2,1-2H3,(H,20,23)/t;;20-;;;;;/m..1...../s1
InChIKeyZRSOFYDLFJVORA-YHGOZYOXSA-N
MW3423.23 g/mol
LogP30.07
Rot. Bonds36

About 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide

4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide (PubChem CID 162202163) has the molecular formula C154H190F9N27O26S13 and a molecular weight of 3423.23 g/mol. Its IUPAC name is 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide.

Molecular Properties

Compound Name4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide
PubChem CID162202163
Molecular FormulaC154H190F9N27O26S13
Molecular Weight3423.23 g/mol
Exact Mass3420.06
IUPAC Name4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide
SMILESCC(C)(C1CCN(C(=O)Nc2ccns2)CC1)S(=O)(=O)c1cc(F)cc(F)c1.CC(C)(C1CCN(C(=O)Nc2cnns2)CC1)S(=O)(=O)c1cccc(F)c1.CC(F)(F)Oc1ccc(S(=O)(=O)C2(C3CCN(C(=O)Nc4ccns4)CC3)CC2)cc1.COc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1cc(NC(=O)N2CCC([C@](C)(F)S(=O)(=O)c3cc(C(C)(F)F)nn3C)CC2)ccn1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccns2)CC1.O=C(Nc1ccns1)N1CCC(C2(S(=O)(=O)c3cccc(F)c3)CC2)CC1
InChIInChI=1S/C21H27N3O4S.C21H27N3O3S.C20H26F3N5O3S.C20H23F2N3O4S2.C19H25N3O3S2.C18H21F2N3O3S2.C18H20FN3O3S2.C17H21FN4O3S2/c1-21(2,29(26,27)19-7-5-4-6-18(19)28-3)16-10-14-24(15-11-16)20(25)23-17-8-12-22-13-9-17;1-16-6-4-5-7-19(16)28(26,27)21(2,3)17-10-14-24(15-11-17)20(25)23-18-8-12-22-13-9-18;1-13-11-15(5-8-24-13)25-18(29)28-9-6-14(7-10-28)20(3,23)32(30,31)17-12-16(19(2,21)22)26-27(17)4;1-19(21,22)29-15-2-4-16(5-3-15)31(27,28)20(9-10-20)14-7-12-25(13-8-14)18(26)24-17-6-11-23-30-17;1-14-6-4-5-7-16(14)27(24,25)19(2,3)15-9-12-22(13-10-15)18(23)21-17-8-11-20-26-17;1-18(2,28(25,26)15-10-13(19)9-14(20)11-15)12-4-7-23(8-5-12)17(24)22-16-3-6-21-27-16;19-14-2-1-3-15(12-14)27(24,25)18(7-8-18)13-5-10-22(11-6-13)17(23)21-16-4-9-20-26-16;1-17(2,27(24,25)14-5-3-4-13(18)10-14)12-6-8-22(9-7-12)16(23)20-15-11-19-21-26-15/h4-9,12-13,16H,10-11,14-15H2,1-3H3,(H,22,23,25);4-9,12-13,17H,10-11,14-15H2,1-3H3,(H,22,23,25);5,8,11-12,14H,6-7,9-10H2,1-4H3,(H,24,25,29);2-6,11,14H,7-10,12-13H2,1H3,(H,24,26);4-8,11,15H,9-10,12-13H2,1-3H3,(H,21,23);3,6,9-12H,4-5,7-8H2,1-2H3,(H,22,24);1-4,9,12-13H,5-8,10-11H2,(H,21,23);3-5,10-12H,6-9H2,1-2H3,(H,20,23)/t;;20-;;;;;/m..1...../s1
InChIKeyZRSOFYDLFJVORA-YHGOZYOXSA-N
XLogP30.07
TPSA684.13 Ų
H-Bond Donors8
H-Bond Acceptors42
Rotatable Bonds36
Heavy Atoms229
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003423.23
LogP ≤ 530.07
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1042

Analyze 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide with MolForge

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Related Compounds

1-(4-fluorophenyl)-N-[(1S)-1-(4-methoxy-3-methylsulfonylphenyl)propyl]-5-(trifluoromethyl)-6,7-dihydro-5H-pyrazolo[4,5-b]pyridine-4-carboxamide;bis(1-(4-fluorophenyl)-5-methyl-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)butyl]-6,7-dihydro-5H-pyrazolo[4,5-b]pyridine-4-carboxamide);bis(1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)butyl]-6-(trifluoromethyl)-6,7-dihydro-5H-pyrazolo[4,5-b]pyridine-4-carboxamide)
CID 157247451
4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[(1R)-1-[3-(difluoromethyl)-1-methylpyrazol-4-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[1-fluoro-1-(3-methylphenyl)sulfonylethyl]-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide;4-[1-fluoro-1-(3-methylphenyl)sulfonylethyl]-N-(1,2-oxazol-4-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-methylphenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide
CID 157934711
4-[2-(2-chlorophenyl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluoro-5-methylphenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluoro-5-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(2-methylphenyl)sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(3-methylphenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide
CID 158568199
4-[2-(2-chlorophenyl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;N-(1,6-dihydropyridazin-5-yl)-4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]piperidine-1-carboxamide;4-[1-(3-fluoro-5-methylphenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-(2-indolizin-7-ylsulfonylpropan-2-yl)-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-(2-methylphenyl)sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-(2-pyrazolo[1,5-a]pyridin-6-ylsulfonylpropan-2-yl)-N-pyridazin-4-ylpiperidine-1-carboxamide
CID 159700011
4-[2-(2-chlorophenyl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[1-(3-fluoro-5-methylphenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-(2-indolizin-7-ylsulfonylpropan-2-yl)-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-(2-methylphenyl)sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-(2-pyrazolo[1,5-a]pyridin-6-ylsulfonylpropan-2-yl)-N-pyridazin-4-ylpiperidine-1-carboxamide
CID 159957524
4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluoro-5-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-methylphenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(3-methylphenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide
CID 161193572
4-[2-(2-chlorophenyl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[1-(3,5-difluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(2-methylphenyl)sulfonylcyclopropyl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[2-(1-methylpyrrol-2-yl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-(2-pyrazolo[1,5-a]pyridin-5-ylsulfonylpropan-2-yl)-N-pyridazin-4-ylpiperidine-1-carboxamide
CID 161531123
4-[(2-chloro-5-methoxyphenyl)sulfonyl-difluoromethyl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[[2-chloro-5-(trifluoromethoxy)phenyl]sulfonyl-difluoromethyl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[1-(2-cyanophenyl)sulfonyl-1-fluoroethyl]-N-pyridazin-4-ylpiperidine-1-carboxamide;4-[2-(2,5-dimethylpyrazol-3-yl)sulfonylpropan-2-yl]-N-(6-fluoro-3-pyridinyl)piperidine-1-carboxamide;4-[2-[3-(1-fluoroethyl)-1-methylpyrazol-5-yl]sulfonylpropan-2-yl]-N-(2-fluoro-4-pyridinyl)piperidine-1-carboxamide;4-[1-fluoro-1-(3-fluorophenyl)sulfonylethyl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[1-fluoro-1-(2-methylphenyl)sulfonylethyl]-N-pyridazin-4-ylpiperidine-1-carboxamide
CID 162064886

Frequently Asked Questions

What is the IUPAC name of 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide?
The IUPAC name of 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide (CID 162202163) is 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide.
What is the SMILES notation for 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide?
The canonical SMILES for 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide is CC(C)(C1CCN(C(=O)Nc2ccns2)CC1)S(=O)(=O)c1cc(F)cc(F)c1.CC(C)(C1CCN(C(=O)Nc2cnns2)CC1)S(=O)(=O)c1cccc(F)c1.CC(F)(F)Oc1ccc(S(=O)(=O)C2(C3CCN(C(=O)Nc4ccns4)CC3)CC2)cc1.COc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1cc(NC(=O)N2CCC([C@](C)(F)S(=O)(=O)c3cc(C(C)(F)F)nn3C)CC2)ccn1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccncc2)CC1.Cc1ccccc1S(=O)(=O)C(C)(C)C1CCN(C(=O)Nc2ccns2)CC1.O=C(Nc1ccns1)N1CCC(C2(S(=O)(=O)c3cccc(F)c3)CC2)CC1.
What is the InChIKey of 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide?
The InChIKey is ZRSOFYDLFJVORA-YHGOZYOXSA-N. The full InChI is InChI=1S/C21H27N3O4S.C21H27N3O3S.C20H26F3N5O3S.C20H23F2N3O4S2.C19H25N3O3S2.C18H21F2N3O3S2.C18H20FN3O3S2.C17H21FN4O3S2/c1-21(2,29(26,27)19-7-5-4-6-18(19)28-3)16-10-14-24(15-11-16)20(25)23-17-8-12-22-13-9-17;1-16-6-4-5-7-19(16)28(26,27)21(2,3)17-10-14-24(15-11-17)20(25)23-18-8-12-22-13-9-18;1-13-11-15(5-8-24-13)25-18(29)28-9-6-14(7-10-28)20(3,23)32(30,31)17-12-16(19(2,21)22)26-27(17)4;1-19(21,22)29-15-2-4-16(5-3-15)31(27,28)20(9-10-20)14-7-12-25(13-8-14)18(26)24-17-6-11-23-30-17;1-14-6-4-5-7-16(14)27(24,25)19(2,3)15-9-12-22(13-10-15)18(23)21-17-8-11-20-26-17;1-18(2,28(25,26)15-10-13(19)9-14(20)11-15)12-4-7-23(8-5-12)17(24)22-16-3-6-21-27-16;19-14-2-1-3-15(12-14)27(24,25)18(7-8-18)13-5-10-22(11-6-13)17(23)21-16-4-9-20-26-16;1-17(2,27(24,25)14-5-3-4-13(18)10-14)12-6-8-22(9-7-12)16(23)20-15-11-19-21-26-15/h4-9,12-13,16H,10-11,14-15H2,1-3H3,(H,22,23,25);4-9,12-13,17H,10-11,14-15H2,1-3H3,(H,22,23,25);5,8,11-12,14H,6-7,9-10H2,1-4H3,(H,24,25,29);2-6,11,14H,7-10,12-13H2,1H3,(H,24,26);4-8,11,15H,9-10,12-13H2,1-3H3,(H,21,23);3,6,9-12H,4-5,7-8H2,1-2H3,(H,22,24);1-4,9,12-13H,5-8,10-11H2,(H,21,23);3-5,10-12H,6-9H2,1-2H3,(H,20,23)/t;;20-;;;;;/m..1...../s1.
What are the key properties of 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide?
4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide has a molecular weight of 3423.23 g/mol, XLogP of 30.07, 36 rotatable bonds, 8 hydrogen bond donors, and 42 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[1-[4-(1,1-difluoroethoxy)phenyl]sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[(1R)-1-[3-(1,1-difluoroethyl)-1-methylpyrazol-5-yl]sulfonyl-1-fluoroethyl]-N-(2-methyl-4-pyridinyl)piperidine-1-carboxamide;4-[2-(3,5-difluorophenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[1-(3-fluorophenyl)sulfonylcyclopropyl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide;4-[2-(3-fluorophenyl)sulfonylpropan-2-yl]-N-(thiadiazol-5-yl)piperidine-1-carboxamide;4-[2-(2-methoxyphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-pyridin-4-ylpiperidine-1-carboxamide;4-[2-(2-methylphenyl)sulfonylpropan-2-yl]-N-(1,2-thiazol-5-yl)piperidine-1-carboxamide is sourced from PubChem (CID 162202163), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).