6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine

C102H96BrClF2N24O5S2 — CID 162204364

IUPAC6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
SMILESCN1CC[C@@H](Oc2cc(Nc3ncc4cc(Cl)ccc4n3)cc(-c3cnn(C)c3)c2)C1.COc1ccc(-c2ccc(Nc3ncc4cc(-c5nccs5)c(OC5CCNCC5)cc4n3)cc2)cn1.COc1ncccc1-c1ccc(Nc2ncc3cc(-c4nccs4)c(OC4CCNCC4)cc3n2)cc1.Cn1cc(-c2cc(CN3CCC(F)(F)C3)cc(Nc3ncc4cc(Br)ccc4n3)c2)cn1
InChIInChI=1S/2C28H26N6O2S.C23H21BrF2N6.C23H23ClN6O/c1-35-26-7-4-19(16-31-26)18-2-5-21(6-3-18)33-28-32-17-20-14-23(27-30-12-13-37-27)25(15-24(20)34-28)36-22-8-10-29-11-9-22;1-35-26-22(3-2-10-30-26)18-4-6-20(7-5-18)33-28-32-17-19-15-23(27-31-13-14-37-27)25(16-24(19)34-28)36-21-8-11-29-12-9-21;1-31-13-18(11-28-31)16-6-15(12-32-5-4-23(25,26)14-32)7-20(9-16)29-22-27-10-17-8-19(24)2-3-21(17)30-22;1-29-6-5-20(14-29)31-21-9-15(17-12-26-30(2)13-17)8-19(10-21)27-23-25-11-16-7-18(24)3-4-22(16)28-23/h2-7,12-17,22,29H,8-11H2,1H3,(H,32,33,34);2-7,10,13-17,21,29H,8-9,11-12H2,1H3,(H,32,33,34);2-3,6-11,13H,4-5,12,14H2,1H3,(H,27,29,30);3-4,7-13,20H,5-6,14H2,1-2H3,(H,25,27,28)/t;;;20-/m...1/s1
InChIKeyZRZNLRMLXWCDLE-ZAWNVZJDSA-N
MW1955.54 g/mol
LogP21.28
Rot. Bonds24

About 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine

6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine (PubChem CID 162204364) has the molecular formula C102H96BrClF2N24O5S2 and a molecular weight of 1955.54 g/mol. Its IUPAC name is 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine.

Molecular Properties

Compound Name6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
PubChem CID162204364
Molecular FormulaC102H96BrClF2N24O5S2
Molecular Weight1955.54 g/mol
Exact Mass1952.63
IUPAC Name6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
SMILESCN1CC[C@@H](Oc2cc(Nc3ncc4cc(Cl)ccc4n3)cc(-c3cnn(C)c3)c2)C1.COc1ccc(-c2ccc(Nc3ncc4cc(-c5nccs5)c(OC5CCNCC5)cc4n3)cc2)cn1.COc1ncccc1-c1ccc(Nc2ncc3cc(-c4nccs4)c(OC4CCNCC4)cc3n2)cc1.Cn1cc(-c2cc(CN3CCC(F)(F)C3)cc(Nc3ncc4cc(Br)ccc4n3)c2)cn1
InChIInChI=1S/2C28H26N6O2S.C23H21BrF2N6.C23H23ClN6O/c1-35-26-7-4-19(16-31-26)18-2-5-21(6-3-18)33-28-32-17-20-14-23(27-30-12-13-37-27)25(15-24(20)34-28)36-22-8-10-29-11-9-22;1-35-26-22(3-2-10-30-26)18-4-6-20(7-5-18)33-28-32-17-19-15-23(27-31-13-14-37-27)25(16-24(19)34-28)36-21-8-11-29-12-9-21;1-31-13-18(11-28-31)16-6-15(12-32-5-4-23(25,26)14-32)7-20(9-16)29-22-27-10-17-8-19(24)2-3-21(17)30-22;1-29-6-5-20(14-29)31-21-9-15(17-12-26-30(2)13-17)8-19(10-21)27-23-25-11-16-7-18(24)3-4-22(16)28-23/h2-7,12-17,22,29H,8-11H2,1H3,(H,32,33,34);2-7,10,13-17,21,29H,8-9,11-12H2,1H3,(H,32,33,34);2-3,6-11,13H,4-5,12,14H2,1H3,(H,27,29,30);3-4,7-13,20H,5-6,14H2,1-2H3,(H,25,27,28)/t;;;20-/m...1/s1
InChIKeyZRZNLRMLXWCDLE-ZAWNVZJDSA-N
XLogP21.28
TPSA315.13 Ų
H-Bond Donors6
H-Bond Acceptors31
Rotatable Bonds24
Heavy Atoms137
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001955.54
LogP ≤ 521.28
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1031

Analyze 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-bromo-N-[3-[(4,4-difluoropiperidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;N-[3-[(4,4-difluoropiperidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]-6-ethynylquinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 158343668
N-[4-(difluoromethyl)phenyl]-7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;6-ethynyl-8-methoxy-N-[3-(1-methylpyrazol-4-yl)-5-(morpholin-4-ylmethyl)phenyl]quinazolin-2-amine;6-ethynyl-N-[3-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;1-[4-[[7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)quinazolin-2-yl]amino]phenyl]pyrrolidin-2-one
CID 157550681
8-chloro-6-cyclopropyl-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;8-chloro-6-methyl-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;7-(1-methylpiperidin-4-yl)oxy-N-[3-(1H-pyrazol-5-yl)phenyl]-6-(1,3-thiazol-2-yl)quinazolin-2-amine;7-piperidin-4-yloxy-N-[3-(1H-pyrazol-5-yl)phenyl]-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 157701025
6-ethynyl-8-methoxy-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;6-ethynyl-8-methoxy-N-[3-(1-methylpyrazol-4-yl)-5-[(3S)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-fluoro-3-(1-methylpyrazol-4-yl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;7-piperidin-4-yloxy-N-[4-(pyrazol-1-ylmethyl)phenyl]-6-pyridin-3-ylquinazolin-2-amine
CID 157912886
6-bromo-N-[3-[2-(diethylamino)ethoxy]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;4-[[3-[(6-ethynyl-8-methoxyquinazolin-2-yl)amino]-5-(1-methylpyrazol-4-yl)phenyl]methyl]piperazin-2-one;N-[3-(oxan-4-yl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;7-piperidin-4-yloxy-N-[4-(1H-pyrazol-5-ylmethyl)phenyl]-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 157936276
6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;6-ethynyl-N-[3-(methylaminomethyl)phenyl]-7-(pyridin-3-ylmethoxy)quinazolin-2-amine;2-(3-fluoroanilino)-N-methyl-7-piperidin-4-yloxyquinazoline-6-carboxamide;[2-(3-fluoroanilino)-7-piperidin-4-yloxyquinazolin-6-yl]-morpholin-4-ylmethanone;7-piperidin-4-yloxy-N-(4-pyridin-3-ylphenyl)-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 159055529
N-[4-(6-amino-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;6-bromo-8-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;8-chloro-6-ethynyl-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methylpyrimidin-5-yl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 159316275
8-chloro-6-ethynyl-N-[3-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;6-ethynyl-8-fluoro-N-[3-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)-N-[4-(1H-1,2,4-triazol-5-yl)phenyl]quinazolin-2-amine;7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)-N-[4-(1H-1,2,4-triazol-5-yl)phenyl]quinazolin-2-amine
CID 160201429
6-bromo-8-methyl-N-[3-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;6-bromo-N-[3-[(3R)-pyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(difluoromethyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;[3-[[7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-yl]amino]phenyl]methanesulfonamide
CID 160327423
8-chloro-6-ethynyl-N-[3-(1-methylpyrazol-4-yl)-5-(piperidin-1-ylmethyl)phenyl]quinazolin-2-amine;N-[3-(2,3-dihydrothiadiazol-4-yl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;6-ethynyl-8-fluoro-N-[3-(1-methylpyrazol-4-yl)-5-(piperidin-1-ylmethyl)phenyl]quinazolin-2-amine;1-[4-[[7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-yl]amino]phenyl]pyrrolidin-2-one
CID 160771011
6-bromo-8-fluoro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;6-bromo-8-methoxy-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;7-(1-methylpiperidin-4-yl)oxy-N-(4-pyridin-3-ylphenyl)-6-(1,3-thiazol-2-yl)quinazolin-2-amine;7-(1-methylpiperidin-4-yl)oxy-N-(4-pyridin-4-ylphenyl)-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 161008799
N-[3-(2-amino-4-pyridinyl)-5-(morpholin-4-ylmethyl)phenyl]-6-ethynylquinazolin-2-amine;[2-(2-anilino-7-piperidin-4-yloxyquinazolin-6-yl)-1,3-thiazol-4-yl]methanol;6-bromo-N-[3-(morpholin-4-ylmethyl)-5-pyrimidin-5-ylphenyl]quinazolin-2-amine;6-ethynyl-N-[3-[(4-methylpiperazin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;N-[3-(5-methoxy-3-pyridinyl)phenyl]-7-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine
CID 161266362

Frequently Asked Questions

What is the IUPAC name of 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine?
The IUPAC name of 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine (CID 162204364) is 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine.
What is the SMILES notation for 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine?
The canonical SMILES for 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine is CN1CC[C@@H](Oc2cc(Nc3ncc4cc(Cl)ccc4n3)cc(-c3cnn(C)c3)c2)C1.COc1ccc(-c2ccc(Nc3ncc4cc(-c5nccs5)c(OC5CCNCC5)cc4n3)cc2)cn1.COc1ncccc1-c1ccc(Nc2ncc3cc(-c4nccs4)c(OC4CCNCC4)cc3n2)cc1.Cn1cc(-c2cc(CN3CCC(F)(F)C3)cc(Nc3ncc4cc(Br)ccc4n3)c2)cn1.
What is the InChIKey of 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine?
The InChIKey is ZRZNLRMLXWCDLE-ZAWNVZJDSA-N. The full InChI is InChI=1S/2C28H26N6O2S.C23H21BrF2N6.C23H23ClN6O/c1-35-26-7-4-19(16-31-26)18-2-5-21(6-3-18)33-28-32-17-20-14-23(27-30-12-13-37-27)25(15-24(20)34-28)36-22-8-10-29-11-9-22;1-35-26-22(3-2-10-30-26)18-4-6-20(7-5-18)33-28-32-17-19-15-23(27-31-13-14-37-27)25(16-24(19)34-28)36-21-8-11-29-12-9-21;1-31-13-18(11-28-31)16-6-15(12-32-5-4-23(25,26)14-32)7-20(9-16)29-22-27-10-17-8-19(24)2-3-21(17)30-22;1-29-6-5-20(14-29)31-21-9-15(17-12-26-30(2)13-17)8-19(10-21)27-23-25-11-16-7-18(24)3-4-22(16)28-23/h2-7,12-17,22,29H,8-11H2,1H3,(H,32,33,34);2-7,10,13-17,21,29H,8-9,11-12H2,1H3,(H,32,33,34);2-3,6-11,13H,4-5,12,14H2,1H3,(H,27,29,30);3-4,7-13,20H,5-6,14H2,1-2H3,(H,25,27,28)/t;;;20-/m...1/s1.
What are the key properties of 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine?
6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine has a molecular weight of 1955.54 g/mol, XLogP of 21.28, 24 rotatable bonds, 6 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 6-bromo-N-[3-[(3,3-difluoropyrrolidin-1-yl)methyl]-5-(1-methylpyrazol-4-yl)phenyl]quinazolin-2-amine;6-chloro-N-[3-(1-methylpyrazol-4-yl)-5-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]quinazolin-2-amine;N-[4-(2-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine;N-[4-(6-methoxy-3-pyridinyl)phenyl]-7-piperidin-4-yloxy-6-(1,3-thiazol-2-yl)quinazolin-2-amine is sourced from PubChem (CID 162204364), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).