N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone

C126H144F7N33O20 — CID 162214772

About N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone

N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone (PubChem CID 162214772) has the molecular formula C126H144F7N33O20 and a molecular weight of 2573.73 g/mol. Its IUPAC name is N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone.

Molecular Properties

• Compound Name: N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone
• PubChem CID: 162214772
• Molecular Formula: C126H144F7N33O20
• Molecular Weight: 2573.73 g/mol
• Exact Mass: 2572.12
• IUPAC Name: N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone
• SMILES: CCN(Cc1cc(F)ccc1F)C(=O)C1=NCc2ncnc(N[C@@H]3COCC[C@H]3O)c21.CCN1C[C@@H](O)[C@H](Nc2ncnc3c2C(C(=O)N[C@H](C)c2cc(F)ccc2F)=NC3)C1.COc1cc(C)cc(CN(C)C(=O)C2=NCc3ncnc(N[C@@H]4CC[C@@H](O)[C@H]4O)c32)c1.COc1ccc(F)cc1CN(C)C(=O)C1=NCc2ncnc(N[C@@H]3CC[C@@H](O)[C@H]3O)c21.COc1ncc(F)cc1CN(C)C(=O)C1=NCc2ncnc(N[C@@H]3CC[C@@H](O)[C@H]3O)c21.Cc1cncc(C2C[C@H](F)CN2C(=O)C2=NCc3ncnc(N[C@@H]4COC[C@H]4O)c32)c1
• InChI: InChI=1S/C22H27N5O4.C21H24F2N6O2.C21H23F2N5O3.C21H23FN6O3.C21H24FN5O4.C20H23FN6O4/c1-12-6-13(8-14(7-12)31-3)10-27(2)22(30)19-18-16(9-23-19)24-11-25-21(18)26-15-4-5-17(28)20(15)29;1-3-29-8-16(17(30)9-29)28-20-18-15(25-10-26-20)7-24-19(18)21(31)27-11(2)13-6-12(22)4-5-14(13)23;1-2-28(9-12-7-13(22)3-4-14(12)23)21(30)19-18-15(8-24-19)25-11-26-20(18)27-16-10-31-6-5-17(16)29;1-11-2-12(5-23-4-11)16-3-13(22)7-28(16)21(30)19-18-14(6-24-19)25-10-26-20(18)27-15-8-31-9-17(15)29;1-27(9-11-7-12(22)3-6-16(11)31-2)21(30)18-17-14(8-23-18)24-10-25-20(17)26-13-4-5-15(28)19(13)29;1-27(8-10-5-11(21)6-23-19(10)31-2)20(30)16-15-13(7-22-16)24-9-25-18(15)26-12-3-4-14(28)17(12)29/h6-8,11,15,17,20,28-29H,4-5,9-10H2,1-3H3,(H,24,25,26);4-6,10-11,16-17,30H,3,7-9H2,1-2H3,(H,27,31)(H,25,26,28);3-4,7,11,16-17,29H,2,5-6,8-10H2,1H3,(H,25,26,27);2,4-5,10,13,15-17,29H,3,6-9H2,1H3,(H,25,26,27);3,6-7,10,13,15,19,28-29H,4-5,8-9H2,1-2H3,(H,24,25,26);5-6,9,12,14,17,28-29H,3-4,7-8H2,1-2H3,(H,24,25,26)/t15-,17-,20+;11-,16-,17-;16-,17-;13-,15+,16?,17+;13-,15-,19+;12-,14-,17+/m111011/s1
• InChIKey: ZTHUQDZDWRSTDL-LXVDPKSTSA-N
• XLogP: 6.26
• TPSA: 688.91 Ų
• H-Bond Donors: 16
• H-Bond Acceptors: 47
• Rotatable Bonds: 34
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2573.73
LogP ≤ 5	6.26
H-Bond Donors ≤ 5	16
H-Bond Acceptors ≤ 10	47

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone?

The IUPAC name of N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone (CID 162214772) is N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone.

What is the SMILES notation for N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone?

The canonical SMILES for N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone is CCN(Cc1cc(F)ccc1F)C(=O)C1=NCc2ncnc(N[C@@H]3COCC[C@H]3O)c21.CCN1C[C@@H](O)[C@H](Nc2ncnc3c2C(C(=O)N[C@H](C)c2cc(F)ccc2F)=NC3)C1.COc1cc(C)cc(CN(C)C(=O)C2=NCc3ncnc(N[C@@H]4CC[C@@H](O)[C@H]4O)c32)c1.COc1ccc(F)cc1CN(C)C(=O)C1=NCc2ncnc(N[C@@H]3CC[C@@H](O)[C@H]3O)c21.COc1ncc(F)cc1CN(C)C(=O)C1=NCc2ncnc(N[C@@H]3CC[C@@H](O)[C@H]3O)c21.Cc1cncc(C2C[C@H](F)CN2C(=O)C2=NCc3ncnc(N[C@@H]4COC[C@H]4O)c32)c1.

What is the InChIKey of N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone?

The InChIKey is ZTHUQDZDWRSTDL-LXVDPKSTSA-N. The full InChI is InChI=1S/C22H27N5O4.C21H24F2N6O2.C21H23F2N5O3.C21H23FN6O3.C21H24FN5O4.C20H23FN6O4/c1-12-6-13(8-14(7-12)31-3)10-27(2)22(30)19-18-16(9-23-19)24-11-25-21(18)26-15-4-5-17(28)20(15)29;1-3-29-8-16(17(30)9-29)28-20-18-15(25-10-26-20)7-24-19(18)21(31)27-11(2)13-6-12(22)4-5-14(13)23;1-2-28(9-12-7-13(22)3-4-14(12)23)21(30)19-18-15(8-24-19)25-11-26-20(18)27-16-10-31-6-5-17(16)29;1-11-2-12(5-23-4-11)16-3-13(22)7-28(16)21(30)19-18-14(6-24-19)25-10-26-20(18)27-15-8-31-9-17(15)29;1-27(9-11-7-12(22)3-6-16(11)31-2)21(30)18-17-14(8-23-18)24-10-25-20(17)26-13-4-5-15(28)19(13)29;1-27(8-10-5-11(21)6-23-19(10)31-2)20(30)16-15-13(7-22-16)24-9-25-18(15)26-12-3-4-14(28)17(12)29/h6-8,11,15,17,20,28-29H,4-5,9-10H2,1-3H3,(H,24,25,26);4-6,10-11,16-17,30H,3,7-9H2,1-2H3,(H,27,31)(H,25,26,28);3-4,7,11,16-17,29H,2,5-6,8-10H2,1H3,(H,25,26,27);2,4-5,10,13,15-17,29H,3,6-9H2,1H3,(H,25,26,27);3,6-7,10,13,15,19,28-29H,4-5,8-9H2,1-2H3,(H,24,25,26);5-6,9,12,14,17,28-29H,3-4,7-8H2,1-2H3,(H,24,25,26)/t15-,17-,20+;11-,16-,17-;16-,17-;13-,15+,16?,17+;13-,15-,19+;12-,14-,17+/m111011/s1.

What are the key properties of N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone?

N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone has a molecular weight of 2573.73 g/mol, XLogP of 6.26, 34 rotatable bonds, 16 hydrogen bond donors, and 47 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1R)-1-(2,5-difluorophenyl)ethyl]-4-[[(3R,4R)-1-ethyl-4-hydroxypyrrolidin-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;N-[(2,5-difluorophenyl)methyl]-N-ethyl-4-[[(3R,4R)-4-hydroxyoxan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxyphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;4-[[(1R,2S,3R)-2,3-dihydroxycyclopentyl]amino]-N-[(3-methoxy-5-methylphenyl)methyl]-N-methyl-7H-pyrrolo[3,4-d]pyrimidine-5-carboxamide;[(4S)-4-fluoro-2-(5-methyl-3-pyridinyl)pyrrolidin-1-yl]-[4-[[(3R,4S)-4-hydroxyoxolan-3-yl]amino]-7H-pyrrolo[3,4-d]pyrimidin-5-yl]methanone is sourced from PubChem (CID 162214772), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).