N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide

C103H73F10N31O11S — CID 162214848

About N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide

N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide (PubChem CID 162214848) has the molecular formula C103H73F10N31O11S and a molecular weight of 2142.97 g/mol. Its IUPAC name is N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide.

Molecular Properties

• Compound Name: N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide
• PubChem CID: 162214848
• Molecular Formula: C103H73F10N31O11S
• Molecular Weight: 2142.97 g/mol
• Exact Mass: 2141.57
• IUPAC Name: N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide
• SMILES: COc1cc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2cc1OC.Cc1ccc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2c1.Cc1cccc2[nH]c(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)nc12.Cc1occc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.O=C(Nc1cn[nH]c1-c1nc2cc3c(cc2[nH]1)OC(F)(F)O3)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1nccs1
• InChI: InChI=1S/C19H15F2N5O3.C18H9F4N5O3.2C18H13F2N5O.C16H13N5O2.C14H10N6OS/c1-28-14-6-11-12(7-15(14)29-2)24-18(23-11)17-13(8-22-26-17)25-19(27)16-9(20)4-3-5-10(16)21;19-7-2-1-3-8(20)14(7)17(28)26-11-6-23-27-15(11)16-24-9-4-12-13(5-10(9)25-16)30-18(21,22)29-12;1-9-4-2-7-12-15(9)24-17(22-12)16-13(8-21-25-16)23-18(26)14-10(19)5-3-6-11(14)20;1-9-5-6-12-13(7-9)23-17(22-12)16-14(8-21-25-16)24-18(26)15-10(19)3-2-4-11(15)20;1-9-10(6-7-23-9)16(22)20-13-8-17-21-14(13)15-18-11-4-2-3-5-12(11)19-15;21-13(14-15-5-6-22-14)19-10-7-16-20-11(10)12-17-8-3-1-2-4-9(8)18-12/h3-8H,1-2H3,(H,22,26)(H,23,24)(H,25,27);1-6H,(H,23,27)(H,24,25)(H,26,28);2-8H,1H3,(H,21,25)(H,22,24)(H,23,26);2-8H,1H3,(H,21,25)(H,22,23)(H,24,26);2-8H,1H3,(H,17,21)(H,18,19)(H,20,22);1-7H,(H,16,20)(H,17,18)(H,19,21)
• InChIKey: ZTICDLLRLJWYFB-UHFFFAOYSA-N
• XLogP: 20.66
• TPSA: 581.71 Ų
• H-Bond Donors: 18
• H-Bond Acceptors: 25
• Rotatable Bonds: 20
• Heavy Atoms: 156
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2142.97
LogP ≤ 5	20.66
H-Bond Donors ≤ 5	18
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide?

The IUPAC name of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide (CID 162214848) is N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide.

What is the SMILES notation for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide?

The canonical SMILES for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide is COc1cc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2cc1OC.Cc1ccc2nc(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)[nH]c2c1.Cc1cccc2[nH]c(-c3[nH]ncc3NC(=O)c3c(F)cccc3F)nc12.Cc1occc1C(=O)Nc1cn[nH]c1-c1nc2ccccc2[nH]1.O=C(Nc1cn[nH]c1-c1nc2cc3c(cc2[nH]1)OC(F)(F)O3)c1c(F)cccc1F.O=C(Nc1cn[nH]c1-c1nc2ccccc2[nH]1)c1nccs1.

What is the InChIKey of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide?

The InChIKey is ZTICDLLRLJWYFB-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H15F2N5O3.C18H9F4N5O3.2C18H13F2N5O.C16H13N5O2.C14H10N6OS/c1-28-14-6-11-12(7-15(14)29-2)24-18(23-11)17-13(8-22-26-17)25-19(27)16-9(20)4-3-5-10(16)21;19-7-2-1-3-8(20)14(7)17(28)26-11-6-23-27-15(11)16-24-9-4-12-13(5-10(9)25-16)30-18(21,22)29-12;1-9-4-2-7-12-15(9)24-17(22-12)16-13(8-21-25-16)23-18(26)14-10(19)5-3-6-11(14)20;1-9-5-6-12-13(7-9)23-17(22-12)16-14(8-21-25-16)24-18(26)15-10(19)3-2-4-11(15)20;1-9-10(6-7-23-9)16(22)20-13-8-17-21-14(13)15-18-11-4-2-3-5-12(11)19-15;21-13(14-15-5-6-22-14)19-10-7-16-20-11(10)12-17-8-3-1-2-4-9(8)18-12/h3-8H,1-2H3,(H,22,26)(H,23,24)(H,25,27);1-6H,(H,23,27)(H,24,25)(H,26,28);2-8H,1H3,(H,21,25)(H,22,24)(H,23,26);2-8H,1H3,(H,21,25)(H,22,23)(H,24,26);2-8H,1H3,(H,17,21)(H,18,19)(H,20,22);1-7H,(H,16,20)(H,17,18)(H,19,21).

What are the key properties of N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide?

N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide has a molecular weight of 2142.97 g/mol, XLogP of 20.66, 20 rotatable bonds, 18 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2-methylfuran-3-carboxamide;N-[5-(1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,3-thiazole-2-carboxamide;N-[5-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;2,6-difluoro-N-[5-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]benzamide;N-[5-(5,6-dimethoxy-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-2,6-difluorobenzamide is sourced from PubChem (CID 162214848), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).