N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine

C90H64F12N20 — CID 162243458

IUPACN-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine
SMILESFC(F)(F)c1ccccc1-c1cc(N2CCCCC2)cc(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cccnc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cnccc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2ncccc2c(Nc2n[nH]c3ccccc23)n1
InChIInChI=1S/C24H22F3N5.3C22H14F3N5/c25-24(26,27)19-10-4-2-8-17(19)21-14-16(32-12-6-1-7-13-32)15-22(28-21)29-23-18-9-3-5-11-20(18)30-31-23;23-22(24,25)16-9-3-1-7-14(16)18-12-13-6-5-11-26-19(13)21(27-18)28-20-15-8-2-4-10-17(15)29-30-20;23-22(24,25)16-9-3-1-6-13(16)19-12-18-15(8-5-11-26-18)20(27-19)28-21-14-7-2-4-10-17(14)29-30-21;23-22(24,25)17-7-3-1-5-15(17)19-11-13-12-26-10-9-14(13)20(27-19)28-21-16-6-2-4-8-18(16)29-30-21/h2-5,8-11,14-15H,1,6-7,12-13H2,(H2,28,29,30,31);3*1-12H,(H2,27,28,29,30)
InChIKeyZWZZMOUSWBVSOY-UHFFFAOYSA-N
MW1653.62 g/mol
LogP24.18
Rot. Bonds13

About N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine

N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine (PubChem CID 162243458) has the molecular formula C90H64F12N20 and a molecular weight of 1653.62 g/mol. Its IUPAC name is N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine.

Molecular Properties

Compound NameN-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine
PubChem CID162243458
Molecular FormulaC90H64F12N20
Molecular Weight1653.62 g/mol
Exact Mass1652.54
IUPAC NameN-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine
SMILESFC(F)(F)c1ccccc1-c1cc(N2CCCCC2)cc(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cccnc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cnccc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2ncccc2c(Nc2n[nH]c3ccccc23)n1
InChIInChI=1S/C24H22F3N5.3C22H14F3N5/c25-24(26,27)19-10-4-2-8-17(19)21-14-16(32-12-6-1-7-13-32)15-22(28-21)29-23-18-9-3-5-11-20(18)30-31-23;23-22(24,25)16-9-3-1-7-14(16)18-12-13-6-5-11-26-19(13)21(27-18)28-20-15-8-2-4-10-17(15)29-30-20;23-22(24,25)16-9-3-1-6-13(16)19-12-18-15(8-5-11-26-18)20(27-19)28-21-14-7-2-4-10-17(14)29-30-21;23-22(24,25)17-7-3-1-5-15(17)19-11-13-12-26-10-9-14(13)20(27-19)28-21-16-6-2-4-8-18(16)29-30-21/h2-5,8-11,14-15H,1,6-7,12-13H2,(H2,28,29,30,31);3*1-12H,(H2,27,28,29,30)
InChIKeyZWZZMOUSWBVSOY-UHFFFAOYSA-N
XLogP24.18
TPSA256.31 Ų
H-Bond Donors8
H-Bond Acceptors16
Rotatable Bonds13
Heavy Atoms122
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001653.62
LogP ≤ 524.18
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1016

Analyze N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine with MolForge

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Related Compounds

7-(2,6-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 44187005
7-(2-Fluoro-4-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1h-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836539
3-(1H-indazol-4-yl)-7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)naphthalen-1-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836649
7-(2,3-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836748
7-(2,5-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836749
3-(1H-indazol-4-yl)-2-(pyridin-4-yl)-7-(2,3,5,6-tetrafluoro-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)pyrazolo[1,5-a]pyrimidine
CID 49836854
3-(7-fluoro-1H-indazol-4-yl)-7-[2-fluoro-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49836965
7-(2,6-Difluoro-4-((1s,4s)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(7-fluoro-1h-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
CID 49836966
7-[4-[(1S,4S)-5-ethyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2,6-difluorophenyl]-3-(1H-indazol-4-yl)-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49837300
7-[2,6-difluoro-4-[(1S,4S)-5-propan-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-3-(1H-indazol-4-yl)-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49837301
7-[2,6-difluoro-4-[(1S,4S)-5-(2-methylpropyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-3-(1H-indazol-4-yl)-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49837401
7-[4-[(1S,4S)-5-cyclobutyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2,6-difluorophenyl]-3-(1H-indazol-4-yl)-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
CID 49837402

Frequently Asked Questions

What is the IUPAC name of N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine?
The IUPAC name of N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine (CID 162243458) is N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine.
What is the SMILES notation for N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine?
The canonical SMILES for N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine is FC(F)(F)c1ccccc1-c1cc(N2CCCCC2)cc(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cccnc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2cnccc2c(Nc2n[nH]c3ccccc23)n1.FC(F)(F)c1ccccc1-c1cc2ncccc2c(Nc2n[nH]c3ccccc23)n1.
What is the InChIKey of N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine?
The InChIKey is ZWZZMOUSWBVSOY-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H22F3N5.3C22H14F3N5/c25-24(26,27)19-10-4-2-8-17(19)21-14-16(32-12-6-1-7-13-32)15-22(28-21)29-23-18-9-3-5-11-20(18)30-31-23;23-22(24,25)16-9-3-1-7-14(16)18-12-13-6-5-11-26-19(13)21(27-18)28-20-15-8-2-4-10-17(15)29-30-20;23-22(24,25)16-9-3-1-6-13(16)19-12-18-15(8-5-11-26-18)20(27-19)28-21-14-7-2-4-10-17(14)29-30-21;23-22(24,25)17-7-3-1-5-15(17)19-11-13-12-26-10-9-14(13)20(27-19)28-21-16-6-2-4-8-18(16)29-30-21/h2-5,8-11,14-15H,1,6-7,12-13H2,(H2,28,29,30,31);3*1-12H,(H2,27,28,29,30).
What are the key properties of N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine?
N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine has a molecular weight of 1653.62 g/mol, XLogP of 24.18, 13 rotatable bonds, 8 hydrogen bond donors, and 16 hydrogen bond acceptors.
Where does this data come from?
All data for N-(1H-indazol-3-yl)-3-[2-(trifluoromethyl)phenyl]-2,6-naphthyridin-1-amine;N-(1H-indazol-3-yl)-6-[2-(trifluoromethyl)phenyl]-1,7-naphthyridin-8-amine;N-(1H-indazol-3-yl)-7-[2-(trifluoromethyl)phenyl]-1,6-naphthyridin-5-amine;N-[4-piperidin-1-yl-6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]-1H-indazol-3-amine is sourced from PubChem (CID 162243458), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).