N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide

C157H174FN29O12S2 — CID 162251189

IUPACN-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCCCOC1CCC(C(C)NC(=O)c2ccn3c(C)cc(-c4ccccn4)nc23)CC1.CCCOC1CCC(CCNC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)NCCc3ccc(-c4ccco4)cn3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3cccs3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3nccs3)ccn12.Cc1cc(C2CCNC2)nc2c(C(=O)NC(C)C3CC3)ccn12.Cc1cc(N2CCOCC2)nc2c(C(=O)NCCc3ccc(OC(C)C)cc3)ccn12
InChIInChI=1S/C26H21FN4O2.2C25H32N4O2.C24H30N4O3.C20H18N4OS.C19H17N5OS.C18H24N4O/c1-17-15-23(18-4-7-20(27)8-5-18)30-25-22(11-13-31(17)25)26(32)28-12-10-21-9-6-19(16-29-21)24-3-2-14-33-24;1-4-15-31-20-10-8-19(9-11-20)18(3)27-25(30)21-12-14-29-17(2)16-23(28-24(21)29)22-7-5-6-13-26-22;1-3-15-31-21-8-6-19(7-9-21)10-13-27-25(30)22-11-14-29-18(2)16-23(28-24(22)29)20-5-4-12-26-17-20;1-17(2)31-20-6-4-19(5-7-20)8-10-25-24(29)21-9-11-28-18(3)16-22(26-23(21)28)27-12-14-30-15-13-27;1-13-11-17(15-5-3-8-21-12-15)23-19-16(7-9-24(13)19)20(25)22-14(2)18-6-4-10-26-18;1-12-10-16(14-4-3-6-20-11-14)23-17-15(5-8-24(12)17)18(25)22-13(2)19-21-7-9-26-19;1-11-9-16(14-5-7-19-10-14)21-17-15(6-8-22(11)17)18(23)20-12(2)13-3-4-13/h2-9,11,13-16H,10,12H2,1H3,(H,28,32);5-7,12-14,16,18-20H,4,8-11,15H2,1-3H3,(H,27,30);4-5,11-12,14,16-17,19,21H,3,6-10,13,15H2,1-2H3,(H,27,30);4-7,9,11,16-17H,8,10,12-15H2,1-3H3,(H,25,29);3-12,14H,1-2H3,(H,22,25);3-11,13H,1-2H3,(H,22,25);6,8-9,12-14,19H,3-5,7,10H2,1-2H3,(H,20,23)
InChIKeyZYAADJKMTYRLQN-UHFFFAOYSA-N
MW2742.44 g/mol
LogP28.09
Rot. Bonds40

About N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide

N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide (PubChem CID 162251189) has the molecular formula C157H174FN29O12S2 and a molecular weight of 2742.44 g/mol. Its IUPAC name is N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide.

Molecular Properties

Compound NameN-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide
PubChem CID162251189
Molecular FormulaC157H174FN29O12S2
Molecular Weight2742.44 g/mol
Exact Mass2740.33
IUPAC NameN-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide
SMILESCCCOC1CCC(C(C)NC(=O)c2ccn3c(C)cc(-c4ccccn4)nc23)CC1.CCCOC1CCC(CCNC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)NCCc3ccc(-c4ccco4)cn3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3cccs3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3nccs3)ccn12.Cc1cc(C2CCNC2)nc2c(C(=O)NC(C)C3CC3)ccn12.Cc1cc(N2CCOCC2)nc2c(C(=O)NCCc3ccc(OC(C)C)cc3)ccn12
InChIInChI=1S/C26H21FN4O2.2C25H32N4O2.C24H30N4O3.C20H18N4OS.C19H17N5OS.C18H24N4O/c1-17-15-23(18-4-7-20(27)8-5-18)30-25-22(11-13-31(17)25)26(32)28-12-10-21-9-6-19(16-29-21)24-3-2-14-33-24;1-4-15-31-20-10-8-19(9-11-20)18(3)27-25(30)21-12-14-29-17(2)16-23(28-24(21)29)22-7-5-6-13-26-22;1-3-15-31-21-8-6-19(7-9-21)10-13-27-25(30)22-11-14-29-18(2)16-23(28-24(22)29)20-5-4-12-26-17-20;1-17(2)31-20-6-4-19(5-7-20)8-10-25-24(29)21-9-11-28-18(3)16-22(26-23(21)28)27-12-14-30-15-13-27;1-13-11-17(15-5-3-8-21-12-15)23-19-16(7-9-24(13)19)20(25)22-14(2)18-6-4-10-26-18;1-12-10-16(14-4-3-6-20-11-14)23-17-15(5-8-24(12)17)18(25)22-13(2)19-21-7-9-26-19;1-11-9-16(14-5-7-19-10-14)21-17-15(6-8-22(11)17)18(23)20-12(2)13-3-4-13/h2-9,11,13-16H,10,12H2,1H3,(H,28,32);5-7,12-14,16,18-20H,4,8-11,15H2,1-3H3,(H,27,30);4-5,11-12,14,16-17,19,21H,3,6-10,13,15H2,1-2H3,(H,27,30);4-7,9,11,16-17H,8,10,12-15H2,1-3H3,(H,25,29);3-12,14H,1-2H3,(H,22,25);3-11,13H,1-2H3,(H,22,25);6,8-9,12-14,19H,3-5,7,10H2,1-2H3,(H,20,23)
InChIKeyZYAADJKMTYRLQN-UHFFFAOYSA-N
XLogP28.09
TPSA467.47 Ų
H-Bond Donors8
H-Bond Acceptors36
Rotatable Bonds40
Heavy Atoms201
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002742.44
LogP ≤ 528.09
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1036

Analyze N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

8-[2-(Dimethylamino)ethyl]-6-[2-fluoro-4-(oxan-4-yl)phenyl]-2-[4-(4-methylmorpholin-2-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[3,5-dimethyl-1-(5-methylthiophen-2-yl)pyrazol-4-yl]-8-phenyl-2-(4-piperidin-3-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;methane;6-[5-methyl-2-(1-methylpiperidin-3-yl)-1,3-thiazol-4-yl]-2-(4-piperidin-4-yloxyanilino)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]-6-[4-methyl-2-(1,3,4-thiadiazol-2-yl)pyrimidin-5-yl]-8-(oxolan-3-yl)pyrido[2,3-d]pyrimidin-7-one
CID 157121912
6-(4-Cyclohexyl-2-fluorophenyl)-8-[2-(dimethylamino)ethyl]-2-[4-(4-methylmorpholin-2-yl)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[3,5-dimethyl-2-(5-methylthiophen-2-yl)-1,3-thiazol-3-ium-4-yl]-8-phenyl-2-(4-piperidin-4-yloxyanilino)pyrido[2,3-d]pyrimidin-7-one;6-[5-methyl-2-(1-methylpiperidin-3-yl)-1,3-thiazol-4-yl]-2-(4-piperidin-4-yloxyanilino)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]-6-[4-methyl-2-(1,3,4-thiadiazol-2-yl)pyrimidin-5-yl]-8-(oxolan-3-yl)pyrido[2,3-d]pyrimidin-7-one
CID 157389647
CID 157454770
CID 157454770
8-[[1-(2,2-Difluoropropylsulfonyl)pyrrol-2-yl]methyl]-6-(pyridin-3-ylamino)-2-[4-(pyrrolidin-3-ylamino)anilino]pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-3-yl)anilino]-6-(1-phenylethenyl)-8-[(3-propan-2-ylsulfonylimidazol-4-yl)methyl]pyrido[2,3-d]pyrimidin-7-one;6-(1-methylpiperidin-2-yl)-8-[(2-methylsulfonylfuran-3-yl)methyl]-2-(4-morpholin-2-ylanilino)pyrido[2,3-d]pyrimidin-7-one;6-(5-methyl-1,3-thiazol-4-yl)-2-(4-pyrrolidin-3-yloxyanilino)-8-[[3-(1,3-thiazol-2-ylsulfinyl)furan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one
CID 157507022
N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methyl-2-(oxan-4-yl)imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-(oxan-4-yl)-N-[2-(4-propoxycyclohexyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-piperidin-4-yl-N-[2,2,2-trifluoro-1-(1,3-thiazol-2-yl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-piperidin-4-yl-N-(2,2,2-trifluoro-1-thiophen-2-ylethyl)imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[2,2,2-trifluoro-1-(4-propoxycyclohexyl)ethyl]imidazo[1,5-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(2,2,2-trifluoro-1-thiophen-2-ylethyl)imidazo[1,5-a]pyrimidine-8-carboxamide
CID 157655987
CID 157721749
CID 157721749
8-[(2-cyclopentylfuran-3-yl)methyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-6-[2-(oxan-2-yl)ethynyl]pyrido[2,3-d]pyrimidin-7-one;6-[2-(diethylamino)ethynyl]-8-(2-methoxyethyl)-2-[4-[methyl(piperidin-4-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;3-[2-(3-fluoro-4-piperazin-1-ylanilino)-7-oxo-8-[(4-propan-2-yl-1,3-thiazol-5-yl)methyl]pyrido[2,3-d]pyrimidin-6-yl]-N,N-dimethylprop-2-ynamide;6-[2-(1-methylimidazol-2-yl)ethynyl]-2-[4-[(1-methylpiperidin-3-yl)amino]anilino]-8-[[3-(trifluoromethyl)furan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one;molecular hydrogen
CID 158240940
6-(4-Cyclohexylphenyl)-2-[4-(4-methylthiomorpholin-2-yl)anilino]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;2-[3-fluoro-4-(2-methylpiperazin-1-yl)anilino]-8-(oxan-4-ylmethyl)-6-[2-(1,3-thiazol-2-yl)pyrimidin-5-yl]pyrido[2,3-d]pyrimidin-7-one;2-[3-fluoro-4-(3-methylpiperazin-1-yl)anilino]-6-(5-piperidin-4-yl-2-pyridinyl)-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-3-yl)oxyanilino]-6-[1-(1-methylpyrrolidin-3-yl)imidazol-2-yl]-8-phenylpyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-4-yl)oxyanilino]-6-(2-piperidin-2-ylphenyl)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one
CID 158413340
6-[5-Methyl-2-(1-methylpiperidin-3-yl)pyrimidin-4-yl]-2-(4-morpholin-2-ylanilino)-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[2-methyl-6-(5-methylthiophen-2-yl)-3-pyridinyl]-2-(4-pyrrolidin-3-yloxyanilino)-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-6-(oxan-4-yl)-3-pyridinyl]-2-[4-(pyrrolidin-3-ylamino)anilino]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;6-[3-methyl-5-(1,3,4-thiadiazol-2-yl)-2-pyridinyl]-2-(4-piperazin-1-ylanilino)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one
CID 158495185
6-[4-(1-Acetylpiperidin-3-yl)-1-methylimidazol-2-yl]-2-(4-piperidin-4-yloxyanilino)-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;6-[2-(1-acetylpiperidin-4-yl)pyrimidin-5-yl]-2-(4-piperidin-3-yloxyanilino)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-(4-methylmorpholin-2-yl)anilino]-8-phenyl-6-[5-(1-prop-1-en-2-ylpyrrolidin-2-yl)-2-pyridinyl]pyrido[2,3-d]pyrimidin-7-one
CID 158555264
CID 158690568
CID 158690568
2-Amino-5-[2-fluoro-5-(furan-3-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-oxazol-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-5-yl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-thiophen-3-ylphenyl)-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 158760585

Frequently Asked Questions

What is the IUPAC name of N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide?
The IUPAC name of N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide (CID 162251189) is N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide.
What is the SMILES notation for N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide?
The canonical SMILES for N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide is CCCOC1CCC(C(C)NC(=O)c2ccn3c(C)cc(-c4ccccn4)nc23)CC1.CCCOC1CCC(CCNC(=O)c2ccn3c(C)cc(-c4cccnc4)nc23)CC1.Cc1cc(-c2ccc(F)cc2)nc2c(C(=O)NCCc3ccc(-c4ccco4)cn3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3cccs3)ccn12.Cc1cc(-c2cccnc2)nc2c(C(=O)NC(C)c3nccs3)ccn12.Cc1cc(C2CCNC2)nc2c(C(=O)NC(C)C3CC3)ccn12.Cc1cc(N2CCOCC2)nc2c(C(=O)NCCc3ccc(OC(C)C)cc3)ccn12.
What is the InChIKey of N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide?
The InChIKey is ZYAADJKMTYRLQN-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H21FN4O2.2C25H32N4O2.C24H30N4O3.C20H18N4OS.C19H17N5OS.C18H24N4O/c1-17-15-23(18-4-7-20(27)8-5-18)30-25-22(11-13-31(17)25)26(32)28-12-10-21-9-6-19(16-29-21)24-3-2-14-33-24;1-4-15-31-20-10-8-19(9-11-20)18(3)27-25(30)21-12-14-29-17(2)16-23(28-24(21)29)22-7-5-6-13-26-22;1-3-15-31-21-8-6-19(7-9-21)10-13-27-25(30)22-11-14-29-18(2)16-23(28-24(22)29)20-5-4-12-26-17-20;1-17(2)31-20-6-4-19(5-7-20)8-10-25-24(29)21-9-11-28-18(3)16-22(26-23(21)28)27-12-14-30-15-13-27;1-13-11-17(15-5-3-8-21-12-15)23-19-16(7-9-24(13)19)20(25)22-14(2)18-6-4-10-26-18;1-12-10-16(14-4-3-6-20-11-14)23-17-15(5-8-24(12)17)18(25)22-13(2)19-21-7-9-26-19;1-11-9-16(14-5-7-19-10-14)21-17-15(6-8-22(11)17)18(23)20-12(2)13-3-4-13/h2-9,11,13-16H,10,12H2,1H3,(H,28,32);5-7,12-14,16,18-20H,4,8-11,15H2,1-3H3,(H,27,30);4-5,11-12,14,16-17,19,21H,3,6-10,13,15H2,1-2H3,(H,27,30);4-7,9,11,16-17H,8,10,12-15H2,1-3H3,(H,25,29);3-12,14H,1-2H3,(H,22,25);3-11,13H,1-2H3,(H,22,25);6,8-9,12-14,19H,3-5,7,10H2,1-2H3,(H,20,23).
What are the key properties of N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide?
N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide has a molecular weight of 2742.44 g/mol, XLogP of 28.09, 40 rotatable bonds, 8 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for N-(1-cyclopropylethyl)-4-methyl-2-pyrrolidin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;2-(4-fluorophenyl)-N-[2-[5-(furan-2-yl)-2-pyridinyl]ethyl]-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-morpholin-4-yl-N-[2-(4-propan-2-yloxyphenyl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[1-(4-propoxycyclohexyl)ethyl]-2-pyridin-2-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-N-[2-(4-propoxycyclohexyl)ethyl]-2-pyridin-3-ylpyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-[1-(1,3-thiazol-2-yl)ethyl]pyrrolo[1,2-a]pyrimidine-8-carboxamide;4-methyl-2-pyridin-3-yl-N-(1-thiophen-2-ylethyl)pyrrolo[1,2-a]pyrimidine-8-carboxamide is sourced from PubChem (CID 162251189), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).