5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine

C284H299BrCl8F6N52O16 — CID 162254557

IUPAC5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine
SMILESCC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)C1CCN(C)CC1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccc(C(F)(F)F)nc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccncc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cncc(Br)c1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cnccc1C(F)(F)F.CCN(Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1)C1CCNCC1.C[C@H]1CNCCN1Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1.Cc1ccc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)cn1.Cc1ccncc1C(=O)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(C)C.Cc1cncc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)c1
InChIInChI=1S/2C29H27ClF3N5O2.C29H30ClN5O2.C29H36ClN5O2.2C29H30ClN5O2.C28H27BrClN5O2.C28H28ClN5O2.C28H34N6.C26H30N6/c1-18(2)38(27(40)22-7-9-26(36-16-22)29(31,32)33)17-20-4-3-5-21(14-20)24-11-13-35-28(37-24)34-12-10-19-6-8-25(39)23(30)15-19;1-18(2)38(27(40)22-16-34-11-9-23(22)29(31,32)33)17-20-4-3-5-21(14-20)25-10-13-36-28(37-25)35-12-8-19-6-7-26(39)24(30)15-19;1-19(2)35(28(37)24-9-7-20(3)33-17-24)18-22-5-4-6-23(15-22)26-12-14-32-29(34-26)31-13-11-21-8-10-27(36)25(30)16-21;1-20(2)35(28(37)23-11-15-34(3)16-12-23)19-22-5-4-6-24(17-22)26-10-14-32-29(33-26)31-13-9-21-7-8-27(36)25(30)18-21;1-19(2)35(28(37)24-17-31-12-9-20(24)3)18-22-5-4-6-23(15-22)26-11-14-33-29(34-26)32-13-10-21-7-8-27(36)25(30)16-21;1-19(2)35(28(37)24-13-20(3)16-31-17-24)18-22-5-4-6-23(14-22)26-10-12-33-29(34-26)32-11-9-21-7-8-27(36)25(30)15-21;1-18(2)35(27(37)22-14-23(29)16-31-15-22)17-20-4-3-5-21(12-20)25-9-11-33-28(34-25)32-10-8-19-6-7-26(36)24(30)13-19;1-19(2)34(27(36)22-9-12-30-13-10-22)18-21-4-3-5-23(16-21)25-11-15-32-28(33-25)31-14-8-20-6-7-26(35)24(29)17-20;1-2-34(25-10-13-29-14-11-25)20-22-4-3-5-23(19-22)27-12-17-32-28(33-27)31-15-8-21-6-7-26-24(18-21)9-16-30-26;1-19-17-27-13-14-32(19)18-21-3-2-4-22(16-21)25-9-12-30-26(31-25)29-10-7-20-5-6-24-23(15-20)8-11-28-24/h3-9,11,13-16,18,39H,10,12,17H2,1-2H3,(H,34,35,37);3-7,9-11,13-16,18,39H,8,12,17H2,1-2H3,(H,35,36,37);4-10,12,14-17,19,36H,11,13,18H2,1-3H3,(H,31,32,34);4-8,10,14,17-18,20,23,36H,9,11-13,15-16,19H2,1-3H3,(H,31,32,33);4-9,11-12,14-17,19,36H,10,13,18H2,1-3H3,(H,32,33,34);4-8,10,12-17,19,36H,9,11,18H2,1-3H3,(H,32,33,34);3-7,9,11-16,18,36H,8,10,17H2,1-2H3,(H,32,33,34);3-7,9-13,15-17,19,35H,8,14,18H2,1-2H3,(H,31,32,33);3-7,9,12,16-19,25,29-30H,2,8,10-11,13-15,20H2,1H3,(H,31,32,33);2-6,8-9,11-12,15-16,19,27-28H,7,10,13-14,17-18H2,1H3,(H,29,30,31)/t;;;;;;;;;19-/m.........0/s1
InChIKeyZYKRMPDYAJTDDJ-PIMYINNESA-N
MW5174.38 g/mol
LogP57.11
Rot. Bonds88

About 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine

5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine (PubChem CID 162254557) has the molecular formula C284H299BrCl8F6N52O16 and a molecular weight of 5174.38 g/mol. Its IUPAC name is 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine.

Molecular Properties

Compound Name5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine
PubChem CID162254557
Molecular FormulaC284H299BrCl8F6N52O16
Molecular Weight5174.38 g/mol
Exact Mass5166.08
IUPAC Name5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine
SMILESCC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)C1CCN(C)CC1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccc(C(F)(F)F)nc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccncc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cncc(Br)c1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cnccc1C(F)(F)F.CCN(Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1)C1CCNCC1.C[C@H]1CNCCN1Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1.Cc1ccc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)cn1.Cc1ccncc1C(=O)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(C)C.Cc1cncc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)c1
InChIInChI=1S/2C29H27ClF3N5O2.C29H30ClN5O2.C29H36ClN5O2.2C29H30ClN5O2.C28H27BrClN5O2.C28H28ClN5O2.C28H34N6.C26H30N6/c1-18(2)38(27(40)22-7-9-26(36-16-22)29(31,32)33)17-20-4-3-5-21(14-20)24-11-13-35-28(37-24)34-12-10-19-6-8-25(39)23(30)15-19;1-18(2)38(27(40)22-16-34-11-9-23(22)29(31,32)33)17-20-4-3-5-21(14-20)25-10-13-36-28(37-25)35-12-8-19-6-7-26(39)24(30)15-19;1-19(2)35(28(37)24-9-7-20(3)33-17-24)18-22-5-4-6-23(15-22)26-12-14-32-29(34-26)31-13-11-21-8-10-27(36)25(30)16-21;1-20(2)35(28(37)23-11-15-34(3)16-12-23)19-22-5-4-6-24(17-22)26-10-14-32-29(33-26)31-13-9-21-7-8-27(36)25(30)18-21;1-19(2)35(28(37)24-17-31-12-9-20(24)3)18-22-5-4-6-23(15-22)26-11-14-33-29(34-26)32-13-10-21-7-8-27(36)25(30)16-21;1-19(2)35(28(37)24-13-20(3)16-31-17-24)18-22-5-4-6-23(14-22)26-10-12-33-29(34-26)32-11-9-21-7-8-27(36)25(30)15-21;1-18(2)35(27(37)22-14-23(29)16-31-15-22)17-20-4-3-5-21(12-20)25-9-11-33-28(34-25)32-10-8-19-6-7-26(36)24(30)13-19;1-19(2)34(27(36)22-9-12-30-13-10-22)18-21-4-3-5-23(16-21)25-11-15-32-28(33-25)31-14-8-20-6-7-26(35)24(29)17-20;1-2-34(25-10-13-29-14-11-25)20-22-4-3-5-23(19-22)27-12-17-32-28(33-27)31-15-8-21-6-7-26-24(18-21)9-16-30-26;1-19-17-27-13-14-32(19)18-21-3-2-4-22(16-21)25-9-12-30-26(31-25)29-10-7-20-5-6-24-23(15-20)8-11-28-24/h3-9,11,13-16,18,39H,10,12,17H2,1-2H3,(H,34,35,37);3-7,9-11,13-16,18,39H,8,12,17H2,1-2H3,(H,35,36,37);4-10,12,14-17,19,36H,11,13,18H2,1-3H3,(H,31,32,34);4-8,10,14,17-18,20,23,36H,9,11-13,15-16,19H2,1-3H3,(H,31,32,33);4-9,11-12,14-17,19,36H,10,13,18H2,1-3H3,(H,32,33,34);4-8,10,12-17,19,36H,9,11,18H2,1-3H3,(H,32,33,34);3-7,9,11-16,18,36H,8,10,17H2,1-2H3,(H,32,33,34);3-7,9-13,15-17,19,35H,8,14,18H2,1-2H3,(H,31,32,33);3-7,9,12,16-19,25,29-30H,2,8,10-11,13-15,20H2,1H3,(H,31,32,33);2-6,8-9,11-12,15-16,19,27-28H,7,10,13-14,17-18H2,1H3,(H,29,30,31)/t;;;;;;;;;19-/m.........0/s1
InChIKeyZYKRMPDYAJTDDJ-PIMYINNESA-N
XLogP57.11
TPSA858.01 Ų
H-Bond Donors22
H-Bond Acceptors58
Rotatable Bonds88
Heavy Atoms367
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005174.38
LogP ≤ 557.11
H-Bond Donors ≤ 522
H-Bond Acceptors ≤ 1058

Analyze 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine?
The IUPAC name of 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine (CID 162254557) is 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine.
What is the SMILES notation for 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine?
The canonical SMILES for 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine is CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)C1CCN(C)CC1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccc(C(F)(F)F)nc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1ccncc1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cncc(Br)c1.CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)c1cnccc1C(F)(F)F.CCN(Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1)C1CCNCC1.C[C@H]1CNCCN1Cc1cccc(-c2ccnc(NCCc3ccc4[nH]ccc4c3)n2)c1.Cc1ccc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)cn1.Cc1ccncc1C(=O)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(C)C.Cc1cncc(C(=O)N(Cc2cccc(-c3ccnc(NCCc4ccc(O)c(Cl)c4)n3)c2)C(C)C)c1.
What is the InChIKey of 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine?
The InChIKey is ZYKRMPDYAJTDDJ-PIMYINNESA-N. The full InChI is InChI=1S/2C29H27ClF3N5O2.C29H30ClN5O2.C29H36ClN5O2.2C29H30ClN5O2.C28H27BrClN5O2.C28H28ClN5O2.C28H34N6.C26H30N6/c1-18(2)38(27(40)22-7-9-26(36-16-22)29(31,32)33)17-20-4-3-5-21(14-20)24-11-13-35-28(37-24)34-12-10-19-6-8-25(39)23(30)15-19;1-18(2)38(27(40)22-16-34-11-9-23(22)29(31,32)33)17-20-4-3-5-21(14-20)25-10-13-36-28(37-25)35-12-8-19-6-7-26(39)24(30)15-19;1-19(2)35(28(37)24-9-7-20(3)33-17-24)18-22-5-4-6-23(15-22)26-12-14-32-29(34-26)31-13-11-21-8-10-27(36)25(30)16-21;1-20(2)35(28(37)23-11-15-34(3)16-12-23)19-22-5-4-6-24(17-22)26-10-14-32-29(33-26)31-13-9-21-7-8-27(36)25(30)18-21;1-19(2)35(28(37)24-17-31-12-9-20(24)3)18-22-5-4-6-23(15-22)26-11-14-33-29(34-26)32-13-10-21-7-8-27(36)25(30)16-21;1-19(2)35(28(37)24-13-20(3)16-31-17-24)18-22-5-4-6-23(14-22)26-10-12-33-29(34-26)32-11-9-21-7-8-27(36)25(30)15-21;1-18(2)35(27(37)22-14-23(29)16-31-15-22)17-20-4-3-5-21(12-20)25-9-11-33-28(34-25)32-10-8-19-6-7-26(36)24(30)13-19;1-19(2)34(27(36)22-9-12-30-13-10-22)18-21-4-3-5-23(16-21)25-11-15-32-28(33-25)31-14-8-20-6-7-26(35)24(29)17-20;1-2-34(25-10-13-29-14-11-25)20-22-4-3-5-23(19-22)27-12-17-32-28(33-27)31-15-8-21-6-7-26-24(18-21)9-16-30-26;1-19-17-27-13-14-32(19)18-21-3-2-4-22(16-21)25-9-12-30-26(31-25)29-10-7-20-5-6-24-23(15-20)8-11-28-24/h3-9,11,13-16,18,39H,10,12,17H2,1-2H3,(H,34,35,37);3-7,9-11,13-16,18,39H,8,12,17H2,1-2H3,(H,35,36,37);4-10,12,14-17,19,36H,11,13,18H2,1-3H3,(H,31,32,34);4-8,10,14,17-18,20,23,36H,9,11-13,15-16,19H2,1-3H3,(H,31,32,33);4-9,11-12,14-17,19,36H,10,13,18H2,1-3H3,(H,32,33,34);4-8,10,12-17,19,36H,9,11,18H2,1-3H3,(H,32,33,34);3-7,9,11-16,18,36H,8,10,17H2,1-2H3,(H,32,33,34);3-7,9-13,15-17,19,35H,8,14,18H2,1-2H3,(H,31,32,33);3-7,9,12,16-19,25,29-30H,2,8,10-11,13-15,20H2,1H3,(H,31,32,33);2-6,8-9,11-12,15-16,19,27-28H,7,10,13-14,17-18H2,1H3,(H,29,30,31)/t;;;;;;;;;19-/m.........0/s1.
What are the key properties of 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine?
5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine has a molecular weight of 5174.38 g/mol, XLogP of 57.11, 88 rotatable bonds, 22 hydrogen bond donors, and 58 hydrogen bond acceptors.
Where does this data come from?
All data for 5-bromo-N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-1-methyl-N-propan-2-ylpiperidine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-4-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-5-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-6-methyl-N-propan-2-ylpyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-ylpyridine-4-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-4-(trifluoromethyl)pyridine-3-carboxamide;N-[[3-[2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidin-4-yl]phenyl]methyl]-N-propan-2-yl-6-(trifluoromethyl)pyridine-3-carboxamide;4-[3-[[ethyl(piperidin-4-yl)amino]methyl]phenyl]-N-[2-(1H-indol-5-yl)ethyl]pyrimidin-2-amine;N-[2-(1H-indol-5-yl)ethyl]-4-[3-[[(2S)-2-methylpiperazin-1-yl]methyl]phenyl]pyrimidin-2-amine is sourced from PubChem (CID 162254557), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).