tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

C254H254N90O15 — CID 162260433

IUPACtert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)C(O)C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC(C)CC(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CO[C@@H](C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1)c1ccccc1.CO[C@H]1CCN(C(=O)N2CCN(c3cnc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.CO[C@H]1CCN(C(=O)N2CCN(c3ncc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/C29H27N9O2.2C28H25N9O2.C27H29N7O2.2C26H28N10O2.C25H27N9O2.C25H27N9O.2C20H19N9/c1-35-18-24(17-33-35)21-12-25(26-22(13-30)16-34-38(26)19-21)23-14-31-29(32-15-23)37-10-8-36(9-11-37)28(39)27(40-2)20-6-4-3-5-7-20;1-34-17-23(16-32-34)20-11-24(25-21(12-29)15-33-37(25)18-20)22-13-30-28(31-14-22)36-9-7-35(8-10-36)27(39)26(38)19-5-3-2-4-6-19;1-34-17-22(14-32-34)20-11-23(26-21(12-29)13-33-37(26)18-20)24-15-31-25(16-30-24)35-7-9-36(10-8-35)28(39)27(38)19-5-3-2-4-6-19;1-27(2,3)36-26(35)33-11-9-32(10-12-33)23-7-5-19(6-8-23)24-13-20(22-16-29-31(4)17-22)18-34-25(24)21(14-28)15-30-34;1-32-15-21(14-30-32)18-9-23(24-19(10-27)13-31-36(24)16-18)20-11-28-25(29-12-20)33-5-7-34(8-6-33)26(37)35-4-3-22(17-35)38-2;1-32-15-20(12-30-32)18-9-22(25-19(10-27)11-31-36(25)16-18)23-13-29-24(14-28-23)33-5-7-34(8-6-33)26(37)35-4-3-21(17-35)38-2;1-16(2)23(35)24(36)32-4-6-33(7-5-32)25-27-10-19(11-28-25)21-8-17(20-13-29-31(3)14-20)15-34-22(21)18(9-26)12-30-34;1-17(2)8-23(35)32-4-6-33(7-5-32)25-27-11-20(12-28-25)22-9-18(21-14-29-31(3)15-21)16-34-24(22)19(10-26)13-30-34;1-27-12-17(11-25-27)14-6-18(19-15(7-21)10-26-29(19)13-14)16-8-23-20(24-9-16)28-4-2-22-3-5-28;1-27-12-16(9-25-27)14-6-17(20-15(7-21)8-26-29(20)13-14)18-10-24-19(11-23-18)28-4-2-22-3-5-28/h3-7,12,14-19,27H,8-11H2,1-2H3;2-6,11,13-18,26,38H,7-10H2,1H3;2-6,11,13-18,27,38H,7-10H2,1H3;5-8,13,15-18H,9-12H2,1-4H3;9,11-16,22H,3-8,17H2,1-2H3;9,11-16,21H,3-8,17H2,1-2H3;8,10-16,23,35H,4-7H2,1-3H3;9,11-17H,4-8H2,1-3H3;2*6,8-13,22H,2-5H2,1H3/t27-;26-;27-;;22-;21-;;;;/m111.00..../s1
InChIKeyZZEGAUZUVOPRFV-WBTFOCMMSA-N
MW4807.44 g/mol
LogP23.81
Rot. Bonds43

About tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile

tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 162260433) has the molecular formula C254H254N90O15 and a molecular weight of 4807.44 g/mol. Its IUPAC name is tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

Compound Nametert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
PubChem CID162260433
Molecular FormulaC254H254N90O15
Molecular Weight4807.44 g/mol
Exact Mass4804.19
IUPAC Nametert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)C(O)C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC(C)CC(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CO[C@@H](C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1)c1ccccc1.CO[C@H]1CCN(C(=O)N2CCN(c3cnc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.CO[C@H]1CCN(C(=O)N2CCN(c3ncc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/C29H27N9O2.2C28H25N9O2.C27H29N7O2.2C26H28N10O2.C25H27N9O2.C25H27N9O.2C20H19N9/c1-35-18-24(17-33-35)21-12-25(26-22(13-30)16-34-38(26)19-21)23-14-31-29(32-15-23)37-10-8-36(9-11-37)28(39)27(40-2)20-6-4-3-5-7-20;1-34-17-23(16-32-34)20-11-24(25-21(12-29)15-33-37(25)18-20)22-13-30-28(31-14-22)36-9-7-35(8-10-36)27(39)26(38)19-5-3-2-4-6-19;1-34-17-22(14-32-34)20-11-23(26-21(12-29)13-33-37(26)18-20)24-15-31-25(16-30-24)35-7-9-36(10-8-35)28(39)27(38)19-5-3-2-4-6-19;1-27(2,3)36-26(35)33-11-9-32(10-12-33)23-7-5-19(6-8-23)24-13-20(22-16-29-31(4)17-22)18-34-25(24)21(14-28)15-30-34;1-32-15-21(14-30-32)18-9-23(24-19(10-27)13-31-36(24)16-18)20-11-28-25(29-12-20)33-5-7-34(8-6-33)26(37)35-4-3-22(17-35)38-2;1-32-15-20(12-30-32)18-9-22(25-19(10-27)11-31-36(25)16-18)23-13-29-24(14-28-23)33-5-7-34(8-6-33)26(37)35-4-3-21(17-35)38-2;1-16(2)23(35)24(36)32-4-6-33(7-5-32)25-27-10-19(11-28-25)21-8-17(20-13-29-31(3)14-20)15-34-22(21)18(9-26)12-30-34;1-17(2)8-23(35)32-4-6-33(7-5-32)25-27-11-20(12-28-25)22-9-18(21-14-29-31(3)15-21)16-34-24(22)19(10-26)13-30-34;1-27-12-17(11-25-27)14-6-18(19-15(7-21)10-26-29(19)13-14)16-8-23-20(24-9-16)28-4-2-22-3-5-28;1-27-12-16(9-25-27)14-6-17(20-15(7-21)8-26-29(20)13-14)18-10-24-19(11-23-18)28-4-2-22-3-5-28/h3-7,12,14-19,27H,8-11H2,1-2H3;2-6,11,13-18,26,38H,7-10H2,1H3;2-6,11,13-18,27,38H,7-10H2,1H3;5-8,13,15-18H,9-12H2,1-4H3;9,11-16,22H,3-8,17H2,1-2H3;9,11-16,21H,3-8,17H2,1-2H3;8,10-16,23,35H,4-7H2,1-3H3;9,11-17H,4-8H2,1-3H3;2*6,8-13,22H,2-5H2,1H3/t27-;26-;27-;;22-;21-;;;;/m111.00..../s1
InChIKeyZZEGAUZUVOPRFV-WBTFOCMMSA-N
XLogP23.81
TPSA1144.15 Ų
H-Bond Donors5
H-Bond Acceptors95
Rotatable Bonds43
Heavy Atoms359
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004807.44
LogP ≤ 523.81
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1095

Analyze tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile with MolForge

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What is the IUPAC name of tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The IUPAC name of tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 162260433) is tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile.
What is the SMILES notation for tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The canonical SMILES for tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile is CC(C)C(O)C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC(C)CC(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CO[C@@H](C(=O)N1CCN(c2ncc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1)c1ccccc1.CO[C@H]1CCN(C(=O)N2CCN(c3cnc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.CO[C@H]1CCN(C(=O)N2CCN(c3ncc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1.Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)cn3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3cnc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)cn1.
What is the InChIKey of tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The InChIKey is ZZEGAUZUVOPRFV-WBTFOCMMSA-N. The full InChI is InChI=1S/C29H27N9O2.2C28H25N9O2.C27H29N7O2.2C26H28N10O2.C25H27N9O2.C25H27N9O.2C20H19N9/c1-35-18-24(17-33-35)21-12-25(26-22(13-30)16-34-38(26)19-21)23-14-31-29(32-15-23)37-10-8-36(9-11-37)28(39)27(40-2)20-6-4-3-5-7-20;1-34-17-23(16-32-34)20-11-24(25-21(12-29)15-33-37(25)18-20)22-13-30-28(31-14-22)36-9-7-35(8-10-36)27(39)26(38)19-5-3-2-4-6-19;1-34-17-22(14-32-34)20-11-23(26-21(12-29)13-33-37(26)18-20)24-15-31-25(16-30-24)35-7-9-36(10-8-35)28(39)27(38)19-5-3-2-4-6-19;1-27(2,3)36-26(35)33-11-9-32(10-12-33)23-7-5-19(6-8-23)24-13-20(22-16-29-31(4)17-22)18-34-25(24)21(14-28)15-30-34;1-32-15-21(14-30-32)18-9-23(24-19(10-27)13-31-36(24)16-18)20-11-28-25(29-12-20)33-5-7-34(8-6-33)26(37)35-4-3-22(17-35)38-2;1-32-15-20(12-30-32)18-9-22(25-19(10-27)11-31-36(25)16-18)23-13-29-24(14-28-23)33-5-7-34(8-6-33)26(37)35-4-3-21(17-35)38-2;1-16(2)23(35)24(36)32-4-6-33(7-5-32)25-27-10-19(11-28-25)21-8-17(20-13-29-31(3)14-20)15-34-22(21)18(9-26)12-30-34;1-17(2)8-23(35)32-4-6-33(7-5-32)25-27-11-20(12-28-25)22-9-18(21-14-29-31(3)15-21)16-34-24(22)19(10-26)13-30-34;1-27-12-17(11-25-27)14-6-18(19-15(7-21)10-26-29(19)13-14)16-8-23-20(24-9-16)28-4-2-22-3-5-28;1-27-12-16(9-25-27)14-6-17(20-15(7-21)8-26-29(20)13-14)18-10-24-19(11-23-18)28-4-2-22-3-5-28/h3-7,12,14-19,27H,8-11H2,1-2H3;2-6,11,13-18,26,38H,7-10H2,1H3;2-6,11,13-18,27,38H,7-10H2,1H3;5-8,13,15-18H,9-12H2,1-4H3;9,11-16,22H,3-8,17H2,1-2H3;9,11-16,21H,3-8,17H2,1-2H3;8,10-16,23,35H,4-7H2,1-3H3;9,11-17H,4-8H2,1-3H3;2*6,8-13,22H,2-5H2,1H3/t27-;26-;27-;;22-;21-;;;;/m111.00..../s1.
What are the key properties of tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 4807.44 g/mol, XLogP of 23.81, 43 rotatable bonds, 5 hydrogen bond donors, and 95 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl 4-[4-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]phenyl]piperazine-1-carboxylate;4-[2-[4-[(2R)-2-hydroxy-3-methylbutanoyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(2R)-2-methoxy-2-phenylacetyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[5-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrazin-2-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[2-[4-(3-methylbutanoyl)piperazin-1-yl]pyrimidin-5-yl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(5-piperazin-1-ylpyrazin-2-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-(2-piperazin-1-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 162260433), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).