2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride

C128H138ClF3N30O22 — CID 162263228

About 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride

2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride (PubChem CID 162263228) has the molecular formula C128H138ClF3N30O22 and a molecular weight of 2541.15 g/mol. Its IUPAC name is 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride.

Molecular Properties

• Compound Name: 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride
• PubChem CID: 162263228
• Molecular Formula: C128H138ClF3N30O22
• Molecular Weight: 2541.15 g/mol
• Exact Mass: 2539.02
• IUPAC Name: 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride
• SMILES: COc1ccc(F)cc1-c1cc(NC(=O)CC2CC(=O)NC(=O)C2)ncn1.COc1ccc(F)cc1-c1cc(NC(=O)CC2CCNCC2)ncn1.COc1ccc(F)cc1-c1cc(NC(=O)Cc2cc(=O)n(CC(C)C)[nH]2)ncn1.COc1ccccc1-c1cc(NC(=O)CC2CC(=O)NC(=O)C2)ncn1.COc1ccccc1-c1cc(NC(=O)CC2CNC(=O)C2)ncn1.COc1ccccc1-c1cc(NC(=O)CN2CCCC2=O)ncn1.COc1ccccc1-c1cc(NC(=O)Cc2cc(=O)n(CC(C)C)[nH]2)ncn1.Cl
• InChI: InChI=1S/C20H22FN5O3.C20H23N5O3.C18H17FN4O4.C18H21FN4O2.C18H18N4O4.2C17H18N4O3.ClH/c1-12(2)10-26-20(28)8-14(25-26)7-19(27)24-18-9-16(22-11-23-18)15-6-13(21)4-5-17(15)29-3;1-13(2)11-25-20(27)9-14(24-25)8-19(26)23-18-10-16(21-12-22-18)15-6-4-5-7-17(15)28-3;1-27-14-3-2-11(19)7-12(14)13-8-15(21-9-20-13)22-16(24)4-10-5-17(25)23-18(26)6-10;1-25-16-3-2-13(19)9-14(16)15-10-17(22-11-21-15)23-18(24)8-12-4-6-20-7-5-12;1-26-14-5-3-2-4-12(14)13-9-15(20-10-19-13)21-16(23)6-11-7-17(24)22-18(25)8-11;1-24-14-6-3-2-5-12(14)13-9-15(19-11-18-13)20-16(22)10-21-8-4-7-17(21)23;1-24-14-5-3-2-4-12(14)13-8-15(20-10-19-13)21-17(23)7-11-6-16(22)18-9-11;/h4-6,8-9,11-12,25H,7,10H2,1-3H3,(H,22,23,24,27);4-7,9-10,12-13,24H,8,11H2,1-3H3,(H,21,22,23,26);2-3,7-10H,4-6H2,1H3,(H,23,25,26)(H,20,21,22,24);2-3,9-12,20H,4-8H2,1H3,(H,21,22,23,24);2-5,9-11H,6-8H2,1H3,(H,22,24,25)(H,19,20,21,23);2-3,5-6,9,11H,4,7-8,10H2,1H3,(H,18,19,20,22);2-5,8,10-11H,6-7,9H2,1H3,(H,18,22)(H,19,20,21,23);1H
• InChIKey: YSOBMQOKMQDXNT-UHFFFAOYSA-N
• XLogP: 14.68
• TPSA: 678.13 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 39
• Rotatable Bonds: 39
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2541.15
LogP ≤ 5	14.68
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride?

The IUPAC name of 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride (CID 162263228) is 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride.

What is the SMILES notation for 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride?

The canonical SMILES for 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride is COc1ccc(F)cc1-c1cc(NC(=O)CC2CC(=O)NC(=O)C2)ncn1.COc1ccc(F)cc1-c1cc(NC(=O)CC2CCNCC2)ncn1.COc1ccc(F)cc1-c1cc(NC(=O)Cc2cc(=O)n(CC(C)C)[nH]2)ncn1.COc1ccccc1-c1cc(NC(=O)CC2CC(=O)NC(=O)C2)ncn1.COc1ccccc1-c1cc(NC(=O)CC2CNC(=O)C2)ncn1.COc1ccccc1-c1cc(NC(=O)CN2CCCC2=O)ncn1.COc1ccccc1-c1cc(NC(=O)Cc2cc(=O)n(CC(C)C)[nH]2)ncn1.Cl.

What is the InChIKey of 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride?

The InChIKey is YSOBMQOKMQDXNT-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H22FN5O3.C20H23N5O3.C18H17FN4O4.C18H21FN4O2.C18H18N4O4.2C17H18N4O3.ClH/c1-12(2)10-26-20(28)8-14(25-26)7-19(27)24-18-9-16(22-11-23-18)15-6-13(21)4-5-17(15)29-3;1-13(2)11-25-20(27)9-14(24-25)8-19(26)23-18-10-16(21-12-22-18)15-6-4-5-7-17(15)28-3;1-27-14-3-2-11(19)7-12(14)13-8-15(21-9-20-13)22-16(24)4-10-5-17(25)23-18(26)6-10;1-25-16-3-2-13(19)9-14(16)15-10-17(22-11-21-15)23-18(24)8-12-4-6-20-7-5-12;1-26-14-5-3-2-4-12(14)13-9-15(20-10-19-13)21-16(23)6-11-7-17(24)22-18(25)8-11;1-24-14-6-3-2-5-12(14)13-9-15(19-11-18-13)20-16(22)10-21-8-4-7-17(21)23;1-24-14-5-3-2-4-12(14)13-8-15(20-10-19-13)21-17(23)7-11-6-16(22)18-9-11;/h4-6,8-9,11-12,25H,7,10H2,1-3H3,(H,22,23,24,27);4-7,9-10,12-13,24H,8,11H2,1-3H3,(H,21,22,23,26);2-3,7-10H,4-6H2,1H3,(H,23,25,26)(H,20,21,22,24);2-3,9-12,20H,4-8H2,1H3,(H,21,22,23,24);2-5,9-11H,6-8H2,1H3,(H,22,24,25)(H,19,20,21,23);2-3,5-6,9,11H,4,7-8,10H2,1H3,(H,18,19,20,22);2-5,8,10-11H,6-7,9H2,1H3,(H,18,22)(H,19,20,21,23);1H.

What are the key properties of 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride?

2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride has a molecular weight of 2541.15 g/mol, XLogP of 14.68, 39 rotatable bonds, 13 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(2,6-dioxopiperidin-4-yl)-N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]acetamide;2-(2,6-dioxopiperidin-4-yl)-N-[6-(2-methoxyphenyl)pyrimidin-4-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(5-fluoro-2-methoxyphenyl)pyrimidin-4-yl]-2-piperidin-4-ylacetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-[2-(2-methylpropyl)-3-oxo-1H-pyrazol-5-yl]acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[6-(2-methoxyphenyl)pyrimidin-4-yl]-2-(5-oxopyrrolidin-3-yl)acetamide;hydrochloride is sourced from PubChem (CID 162263228), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).