About tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate
tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate (PubChem CID 162378016) has the molecular formula C21H23ClFN7O4
and a molecular weight of 491.91 g/mol. Its IUPAC name is tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate.
Molecular Properties
| Compound Name | tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate |
| PubChem CID | 162378016 |
| Molecular Formula | C21H23ClFN7O4 |
| Molecular Weight | 491.91 g/mol |
| Exact Mass | 491.15 |
| IUPAC Name | tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate |
| SMILES | C[C@@H](OC(=O)Nc1c(-c2ccc(NC(=O)OC(C)(C)C)cn2)nnn1C)c1cc(Cl)cnc1F |
| InChI | InChI=1S/C21H23ClFN7O4/c1-11(14-8-12(22)9-25-17(14)23)33-19(31)27-18-16(28-29-30(18)5)15-7-6-13(10-24-15)26-20(32)34-21(2,3)4/h6-11H,1-5H3,(H,26,32)(H,27,31)/t11-/m1/s1 |
| InChIKey | XJVZJDUYJUUFQC-LLVKDONJSA-N |
| XLogP | 4.72 |
| TPSA | 133.15 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 491.91 |
| LogP ≤ 5 | 4.72 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate?
The IUPAC name of tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate (CID 162378016) is tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate.
What is the SMILES notation for tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate?
The canonical SMILES for tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate is C[C@@H](OC(=O)Nc1c(-c2ccc(NC(=O)OC(C)(C)C)cn2)nnn1C)c1cc(Cl)cnc1F.
What is the InChIKey of tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate?
The InChIKey is XJVZJDUYJUUFQC-LLVKDONJSA-N. The full InChI is InChI=1S/C21H23ClFN7O4/c1-11(14-8-12(22)9-25-17(14)23)33-19(31)27-18-16(28-29-30(18)5)15-7-6-13(10-24-15)26-20(32)34-21(2,3)4/h6-11H,1-5H3,(H,26,32)(H,27,31)/t11-/m1/s1.
What are the key properties of tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate?
tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate has a molecular weight of 491.91 g/mol, XLogP of 4.72, 5 rotatable bonds, 2 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl N-[6-[5-[[(1R)-1-(5-chloro-2-fluoro-3-pyridinyl)ethoxy]carbonylamino]-1-methyltriazol-4-yl]-3-pyridinyl]carbamate is sourced from PubChem (CID 162378016), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).