About 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide
2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide (PubChem CID 162530893) has the molecular formula C23H25FN4O5
and a molecular weight of 456.47 g/mol. Its IUPAC name is 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide.
Molecular Properties
| Compound Name | 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide |
| PubChem CID | 162530893 |
| Molecular Formula | C23H25FN4O5 |
| Molecular Weight | 456.47 g/mol |
| Exact Mass | 456.18 |
| IUPAC Name | 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide |
| SMILES | COc1cc(-c2nc3ccc(C(=O)NC4CCNC4)cc3n2C2(C)COC2)c(F)c(O)c1O |
| InChI | InChI=1S/C23H25FN4O5/c1-23(10-33-11-23)28-16-7-12(22(31)26-13-5-6-25-9-13)3-4-15(16)27-21(28)14-8-17(32-2)19(29)20(30)18(14)24/h3-4,7-8,13,25,29-30H,5-6,9-11H2,1-2H3,(H,26,31) |
| InChIKey | VPNORTCPQNLQMP-UHFFFAOYSA-N |
| XLogP | 2.10 |
| TPSA | 117.87 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 456.47 |
| LogP ≤ 5 | 2.10 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 8 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'catechol_A(92)', 'substructure': 'N/A'}, {'alert_name': 'catechol', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide?
The IUPAC name of 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide (CID 162530893) is 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide.
What is the SMILES notation for 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide?
The canonical SMILES for 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide is COc1cc(-c2nc3ccc(C(=O)NC4CCNC4)cc3n2C2(C)COC2)c(F)c(O)c1O.
What is the InChIKey of 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide?
The InChIKey is VPNORTCPQNLQMP-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25FN4O5/c1-23(10-33-11-23)28-16-7-12(22(31)26-13-5-6-25-9-13)3-4-15(16)27-21(28)14-8-17(32-2)19(29)20(30)18(14)24/h3-4,7-8,13,25,29-30H,5-6,9-11H2,1-2H3,(H,26,31).
What are the key properties of 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide?
2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide has a molecular weight of 456.47 g/mol, XLogP of 2.10, 5 rotatable bonds, 4 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-fluoro-3,4-dihydroxy-5-methoxyphenyl)-3-(3-methyloxetan-3-yl)-N-pyrrolidin-3-ylbenzimidazole-5-carboxamide is sourced from PubChem (CID 162530893), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).