5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole

C11H7F3N4S — CID 162574144

IUPAC5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole
SMILESCc1ccnc(-c2cnc3sc(C(F)(F)F)cn23)n1
InChIInChI=1S/C11H7F3N4S/c1-6-2-3-15-9(17-6)7-4-16-10-18(7)5-8(19-10)11(12,13)14/h2-5H,1H3
InChIKeyLEJWHOOIRWVANS-UHFFFAOYSA-N
MW284.27 g/mol
LogP3.18
Rot. Bonds1

About 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole

5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole (PubChem CID 162574144) has the molecular formula C11H7F3N4S and a molecular weight of 284.27 g/mol. Its IUPAC name is 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole.

Molecular Properties

Compound Name5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole
PubChem CID162574144
Molecular FormulaC11H7F3N4S
Molecular Weight284.27 g/mol
Exact Mass284.03
IUPAC Name5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole
SMILESCc1ccnc(-c2cnc3sc(C(F)(F)F)cn23)n1
InChIInChI=1S/C11H7F3N4S/c1-6-2-3-15-9(17-6)7-4-16-10-18(7)5-8(19-10)11(12,13)14/h2-5H,1H3
InChIKeyLEJWHOOIRWVANS-UHFFFAOYSA-N
XLogP3.18
TPSA43.08 Ų
H-Bond Donors
H-Bond Acceptors5
Rotatable Bonds1
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500284.27
LogP ≤ 53.18
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 105

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Related Compounds

4-[(E)-2-(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)ethenyl]pyrimidin-2-amine
CID 44587324
4-methyl-N-[(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]pyrimidin-2-amine
CID 72890425
6-{[(4,6-Dimethylpyrimidin-2-yl)sulfanyl]methyl}-3-methylimidazo[2,1-b][1,3]thiazole
CID 700769
6-(Pyrimidin-2-ylsulfanylmethyl)imidazo[2,1-b][1,3]thiazole
CID 4447936
2-ethyl-4-{1-[(2-methyl-1,3-thiazol-4-yl)methyl]-1H-imidazol-2-yl}pyrimidine
CID 56872847
2-[2,6-Bis(trifluoromethyl)purin-9-yl]-1,3-thiazole
CID 101540212
3-(Thiazol-2-yl)-7-trifluoromethyl-imidazo[1,2-alpha]pyrimidine
CID 9835150
6-(1,3-Thiazol-2-yl)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidin-4-amine
CID 70843520
6-(5-Methyl-1,3-thiazol-2-yl)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidin-4-amine
CID 70843532
6-(1-Methylimidazol-2-yl)-2-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyrimidin-4-amine
CID 70843562
2-[4-(1,3-Thiazol-2-yl)pyrimidin-2-yl]-4-(trifluoromethyl)-1,3-thiazole
CID 90880835
2-[4-(1-Methylimidazol-2-yl)pyrimidin-2-yl]-4-(trifluoromethyl)-1,3-thiazole
CID 90885050

Frequently Asked Questions

What is the IUPAC name of 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole?
The IUPAC name of 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole (CID 162574144) is 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole.
What is the SMILES notation for 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole?
The canonical SMILES for 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole is Cc1ccnc(-c2cnc3sc(C(F)(F)F)cn23)n1.
What is the InChIKey of 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole?
The InChIKey is LEJWHOOIRWVANS-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H7F3N4S/c1-6-2-3-15-9(17-6)7-4-16-10-18(7)5-8(19-10)11(12,13)14/h2-5H,1H3.
What are the key properties of 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole?
5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole has a molecular weight of 284.27 g/mol, XLogP of 3.18, 1 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(4-methylpyrimidin-2-yl)-2-(trifluoromethyl)imidazo[2,1-b][1,3]thiazole is sourced from PubChem (CID 162574144), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).