About (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one
(3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one (PubChem CID 162657170) has the molecular formula C25H18ClF2NO3S
and a molecular weight of 485.94 g/mol. Its IUPAC name is (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one.
Molecular Properties
| Compound Name | (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one |
| PubChem CID | 162657170 |
| Molecular Formula | C25H18ClF2NO3S |
| Molecular Weight | 485.94 g/mol |
| Exact Mass | 485.07 |
| IUPAC Name | (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one |
| SMILES | O=C1/C(=C/c2cccc(F)c2)CN(S(=O)(=O)c2ccc(Cl)cc2)C/C1=C\c1cccc(F)c1 |
| InChI | InChI=1S/C25H18ClF2NO3S/c26-21-7-9-24(10-8-21)33(31,32)29-15-19(11-17-3-1-5-22(27)13-17)25(30)20(16-29)12-18-4-2-6-23(28)14-18/h1-14H,15-16H2/b19-11+,20-12+ |
| InChIKey | AADJISSXHHWDKU-AYKLPDECSA-N |
| XLogP | 5.36 |
| TPSA | 54.45 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 485.94 |
| LogP ≤ 5 | 5.36 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 3 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'ene_one_ene_A(57)', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one?
The IUPAC name of (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one (CID 162657170) is (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one.
What is the SMILES notation for (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one?
The canonical SMILES for (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one is O=C1/C(=C/c2cccc(F)c2)CN(S(=O)(=O)c2ccc(Cl)cc2)C/C1=C\c1cccc(F)c1.
What is the InChIKey of (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one?
The InChIKey is AADJISSXHHWDKU-AYKLPDECSA-N. The full InChI is InChI=1S/C25H18ClF2NO3S/c26-21-7-9-24(10-8-21)33(31,32)29-15-19(11-17-3-1-5-22(27)13-17)25(30)20(16-29)12-18-4-2-6-23(28)14-18/h1-14H,15-16H2/b19-11+,20-12+.
What are the key properties of (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one?
(3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one has a molecular weight of 485.94 g/mol, XLogP of 5.36, 4 rotatable bonds, 0 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (3E,5E)-1-(4-chlorophenyl)sulfonyl-3,5-bis[(3-fluorophenyl)methylidene]piperidin-4-one is sourced from PubChem (CID 162657170), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).