About 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline
4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline (PubChem CID 162757725) has the molecular formula C18H20F2N6S
and a molecular weight of 390.46 g/mol. Its IUPAC name is 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline.
Molecular Properties
| Compound Name | 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline |
| PubChem CID | 162757725 |
| Molecular Formula | C18H20F2N6S |
| Molecular Weight | 390.46 g/mol |
| Exact Mass | 390.14 |
| IUPAC Name | 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline |
| SMILES | Cc1nc(CN(C)C)sc1-c1cccc(-c2cc(F)c(N)c(NN)c2F)n1 |
| InChI | InChI=1S/C18H20F2N6S/c1-9-18(27-14(23-9)8-26(2)3)13-6-4-5-12(24-13)10-7-11(19)16(21)17(25-22)15(10)20/h4-7,25H,8,21-22H2,1-3H3 |
| InChIKey | CYHOMTMWDWZLFK-UHFFFAOYSA-N |
| XLogP | 3.39 |
| TPSA | 93.09 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 390.46 |
| LogP ≤ 5 | 3.39 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'aniline', 'substructure': 'N/A'}, {'alert_name': 'hydrazine', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline?
The IUPAC name of 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline (CID 162757725) is 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline.
What is the SMILES notation for 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline?
The canonical SMILES for 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline is Cc1nc(CN(C)C)sc1-c1cccc(-c2cc(F)c(N)c(NN)c2F)n1.
What is the InChIKey of 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline?
The InChIKey is CYHOMTMWDWZLFK-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20F2N6S/c1-9-18(27-14(23-9)8-26(2)3)13-6-4-5-12(24-13)10-7-11(19)16(21)17(25-22)15(10)20/h4-7,25H,8,21-22H2,1-3H3.
What are the key properties of 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline?
4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline has a molecular weight of 390.46 g/mol, XLogP of 3.39, 5 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[6-[2-[(dimethylamino)methyl]-4-methyl-1,3-thiazol-5-yl]-2-pyridinyl]-3,6-difluoro-2-hydrazinylaniline is sourced from PubChem (CID 162757725), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).