About 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide
2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide (PubChem CID 163547165) has the molecular formula C26H25Cl2FN4O2S
and a molecular weight of 547.48 g/mol. Its IUPAC name is 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide.
Molecular Properties
| Compound Name | 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide |
| PubChem CID | 163547165 |
| Molecular Formula | C26H25Cl2FN4O2S |
| Molecular Weight | 547.48 g/mol |
| Exact Mass | 546.11 |
| IUPAC Name | 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide |
| SMILES | C[C@H]1CC2(CCN(c3cnc(Sc4cccc(NC(=O)c5cccc(F)c5Cl)c4Cl)cn3)CC2)CO1 |
| InChI | InChI=1S/C26H25Cl2FN4O2S/c1-16-12-26(15-35-16)8-10-33(11-9-26)21-13-31-22(14-30-21)36-20-7-3-6-19(24(20)28)32-25(34)17-4-2-5-18(29)23(17)27/h2-7,13-14,16H,8-12,15H2,1H3,(H,32,34)/t16-/m0/s1 |
| InChIKey | FFZYOLSQWHDDLA-INIZCTEOSA-N |
| XLogP | 6.72 |
| TPSA | 67.35 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 36 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 547.48 |
| LogP ≤ 5 | 6.72 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
Analyze 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide with MolForge
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Frequently Asked Questions
What is the IUPAC name of 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide?
The IUPAC name of 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide (CID 163547165) is 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide.
What is the SMILES notation for 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide?
The canonical SMILES for 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide is C[C@H]1CC2(CCN(c3cnc(Sc4cccc(NC(=O)c5cccc(F)c5Cl)c4Cl)cn3)CC2)CO1.
What is the InChIKey of 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide?
The InChIKey is FFZYOLSQWHDDLA-INIZCTEOSA-N. The full InChI is InChI=1S/C26H25Cl2FN4O2S/c1-16-12-26(15-35-16)8-10-33(11-9-26)21-13-31-22(14-30-21)36-20-7-3-6-19(24(20)28)32-25(34)17-4-2-5-18(29)23(17)27/h2-7,13-14,16H,8-12,15H2,1H3,(H,32,34)/t16-/m0/s1.
What are the key properties of 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide?
2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide has a molecular weight of 547.48 g/mol, XLogP of 6.72, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-chloro-N-[2-chloro-3-[5-[(3S)-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanylphenyl]-3-fluorobenzamide is sourced from PubChem (CID 163547165), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).