7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane

C148H191F24Ir4N5O8SSi8-4 — CID 163647310

About 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane

7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane (PubChem CID 163647310) has the molecular formula C148H191F24Ir4N5O8SSi8-4 and a molecular weight of 3649.76 g/mol. Its IUPAC name is 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane.

Molecular Properties

• Compound Name: 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane
• PubChem CID: 163647310
• Molecular Formula: C148H191F24Ir4N5O8SSi8-4
• Molecular Weight: 3649.76 g/mol
• Exact Mass: 3650.07
• IUPAC Name: 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane
• SMILES: C.CC(C)(C)c1cc(-c2nccc3c4c(ccc23)[Si](C)(C)CC[Si]4(C)C)[c-]c2ccccc12.CCC(CC(F)(F)F)C(=O)C=C(O)C(CC(F)(F)F)CC(F)(F)F.CCC(CC(F)(F)F)C(O)=CC(=O)C(CC(F)(F)F)CC(F)(F)F.CCC(CC)C(=O)C=C(O)C(CC)CC(F)(F)F.CCC(CC)C(=O)C=C(O)C(CC)CC(F)(F)F.Cc1[c-]c(-c2nccc3c4c(ccc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.Cc1[c-]c(-c2nccc3cc4c(cc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.Cc1[c-]c(-c2ncnc3c4c(sc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.[Ir].[Ir].[Ir].[Ir]
• InChI: InChI=1S/C29H34NSi2.2C23H28NSi2.C20H25N2SSi2.2C13H15F9O2.2C13H21F3O2.CH4.4Ir/c1-29(2,3)25-19-21(18-20-10-8-9-11-22(20)25)27-23-12-13-26-28(24(23)14-15-30-27)32(6,7)17-16-31(26,4)5;1-16-11-17(2)13-19(12-16)23-20-15-22-21(14-18(20)7-8-24-23)25(3,4)9-10-26(22,5)6;1-16-13-17(2)15-18(14-16)22-19-7-8-21-23(20(19)9-10-24-22)26(5,6)12-11-25(21,3)4;1-13-9-14(2)11-15(10-13)16-18-17(22-12-21-16)19-20(23-18)25(5,6)8-7-24(19,3)4;2*1-2-7(4-11(14,15)16)9(23)3-10(24)8(5-12(17,18)19)6-13(20,21)22;2*1-4-9(5-2)11(17)7-12(18)10(6-3)8-13(14,15)16;;;;;/h8-15,19H,16-17H2,1-7H3;7-8,11-12,14-15H,9-10H2,1-6H3;7-10,13-14H,11-12H2,1-6H3;9-10,12H,7-8H2,1-6H3;3,7-8,24H,2,4-6H2,1H3;3,7-8,23H,2,4-6H2,1H3;2*7,9-10,18H,4-6,8H2,1-3H3;1H4;;;;/q4*-1
• InChIKey: ZJECEPFOYILTIW-UHFFFAOYSA-N
• XLogP: 42.39
• TPSA: 213.65 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 14
• Rotatable Bonds: 32
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3649.76
LogP ≤ 5	42.39
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	14

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'acyclic_C=C-O', 'substructure': 'N/A'}, {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane?

The IUPAC name of 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane (CID 163647310) is 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane.

What is the SMILES notation for 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane?

The canonical SMILES for 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane is C.CC(C)(C)c1cc(-c2nccc3c4c(ccc23)[Si](C)(C)CC[Si]4(C)C)[c-]c2ccccc12.CCC(CC(F)(F)F)C(=O)C=C(O)C(CC(F)(F)F)CC(F)(F)F.CCC(CC(F)(F)F)C(O)=CC(=O)C(CC(F)(F)F)CC(F)(F)F.CCC(CC)C(=O)C=C(O)C(CC)CC(F)(F)F.CCC(CC)C(=O)C=C(O)C(CC)CC(F)(F)F.Cc1[c-]c(-c2nccc3c4c(ccc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.Cc1[c-]c(-c2nccc3cc4c(cc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.Cc1[c-]c(-c2ncnc3c4c(sc23)[Si](C)(C)CC[Si]4(C)C)cc(C)c1.[Ir].[Ir].[Ir].[Ir].

What is the InChIKey of 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane?

The InChIKey is ZJECEPFOYILTIW-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H34NSi2.2C23H28NSi2.C20H25N2SSi2.2C13H15F9O2.2C13H21F3O2.CH4.4Ir/c1-29(2,3)25-19-21(18-20-10-8-9-11-22(20)25)27-23-12-13-26-28(24(23)14-15-30-27)32(6,7)17-16-31(26,4)5;1-16-11-17(2)13-19(12-16)23-20-15-22-21(14-18(20)7-8-24-23)25(3,4)9-10-26(22,5)6;1-16-13-17(2)15-18(14-16)22-19-7-8-21-23(20(19)9-10-24-22)26(5,6)12-11-25(21,3)4;1-13-9-14(2)11-15(10-13)16-18-17(22-12-21-16)19-20(23-18)25(5,6)8-7-24(19,3)4;2*1-2-7(4-11(14,15)16)9(23)3-10(24)8(5-12(17,18)19)6-13(20,21)22;2*1-4-9(5-2)11(17)7-12(18)10(6-3)8-13(14,15)16;;;;;/h8-15,19H,16-17H2,1-7H3;7-8,11-12,14-15H,9-10H2,1-6H3;7-10,13-14H,11-12H2,1-6H3;9-10,12H,7-8H2,1-6H3;3,7-8,24H,2,4-6H2,1H3;3,7-8,23H,2,4-6H2,1H3;2*7,9-10,18H,4-6,8H2,1-3H3;1H4;;;;/q4*-1;;;;;;;;;.

What are the key properties of 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane?

7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane has a molecular weight of 3649.76 g/mol, XLogP of 42.39, 32 rotatable bonds, 4 hydrogen bond donors, and 14 hydrogen bond acceptors.

Where does this data come from?

All data for 7-(4-tert-butyl-1H-naphthalen-1-id-2-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;bis(3,7-diethyl-9,9,9-trifluoro-6-hydroxynon-5-en-4-one);7-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-f]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-1,1,4,4-tetramethyl-2,3-dihydro-[1,4]disilino[2,3-g]isoquinoline;6-(3,5-dimethylbenzene-6-id-1-yl)-10,10,13,13-tetramethyl-8-thia-3,5-diaza-10,13-disilatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5-tetraene;3-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-7-(2,2,2-trifluoroethyl)non-5-en-4-one;7-ethyl-1,1,1,9,9,9-hexafluoro-6-hydroxy-3-(2,2,2-trifluoroethyl)non-5-en-4-one;tetrakis(iridium);methane is sourced from PubChem (CID 163647310), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).