5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile

C182H183FN54O6S — CID 163662283

IUPAC5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile
SMILESCc1cc(C(C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)ccc1F.Cc1ccc(C(CN)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)cc1.Cc1cccc([C@@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cc1cccc([C@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cn1cc(-c2cc(-c3ccc(N4CCN(CCS(=O)(=O)c5ccccc5)CC4)nc3)n3c(C#N)cnc3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(Cc5ccn(C)n5)CC4)nc3)n3c(C#N)cnc3c2)cn1
InChIInChI=1S/C32H32FN9O.2C32H33N9O.C31H31N9O.C29H28N8O2S.C26H26N10/c1-21-13-22(5-7-27(21)33)31(38(2)3)32(43)41-11-9-40(10-12-41)29-8-6-23(17-35-29)28-14-24(25-18-37-39(4)20-25)15-30-36-19-26(16-34)42(28)30;2*1-22-6-5-7-23(14-22)31(37(2)3)32(42)40-12-10-39(11-13-40)29-9-8-24(18-34-29)28-15-25(26-19-36-38(4)21-26)16-30-35-20-27(17-33)41(28)30;1-21-3-5-22(6-4-21)27(16-33)31(41)39-11-9-38(10-12-39)29-8-7-23(17-34-29)28-13-24(25-18-36-37(2)20-25)14-30-35-19-26(15-32)40(28)30;1-34-21-24(19-33-34)23-15-27(37-25(17-30)20-32-29(37)16-23)22-7-8-28(31-18-22)36-11-9-35(10-12-36)13-14-40(38,39)26-5-3-2-4-6-26;1-32-6-5-22(31-32)18-34-7-9-35(10-8-34)25-4-3-19(14-28-25)24-11-20(21-15-30-33(2)17-21)12-26-29-16-23(13-27)36(24)26/h5-8,13-15,17-20,31H,9-12H2,1-4H3;2*5-9,14-16,18-21,31H,10-13H2,1-4H3;3-8,13-14,17-20,27H,9-12,16,33H2,1-2H3;2-8,15-16,18-21H,9-14H2,1H3;3-6,11-12,14-17H,7-10,18H2,1-2H3/t;2*31-;;;/m.10.../s1
InChIKeyIVKRHNNXNUXEKS-JXGVYDMQSA-N
MW3273.90 g/mol
LogP21.28
Rot. Bonds36

About 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile

5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile (PubChem CID 163662283) has the molecular formula C182H183FN54O6S and a molecular weight of 3273.90 g/mol. Its IUPAC name is 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile.

Molecular Properties

Compound Name5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile
PubChem CID163662283
Molecular FormulaC182H183FN54O6S
Molecular Weight3273.90 g/mol
Exact Mass3271.54
IUPAC Name5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile
SMILESCc1cc(C(C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)ccc1F.Cc1ccc(C(CN)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)cc1.Cc1cccc([C@@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cc1cccc([C@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cn1cc(-c2cc(-c3ccc(N4CCN(CCS(=O)(=O)c5ccccc5)CC4)nc3)n3c(C#N)cnc3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(Cc5ccn(C)n5)CC4)nc3)n3c(C#N)cnc3c2)cn1
InChIInChI=1S/C32H32FN9O.2C32H33N9O.C31H31N9O.C29H28N8O2S.C26H26N10/c1-21-13-22(5-7-27(21)33)31(38(2)3)32(43)41-11-9-40(10-12-41)29-8-6-23(17-35-29)28-14-24(25-18-37-39(4)20-25)15-30-36-19-26(16-34)42(28)30;2*1-22-6-5-7-23(14-22)31(37(2)3)32(42)40-12-10-39(11-13-40)29-9-8-24(18-34-29)28-15-25(26-19-36-38(4)21-26)16-30-35-20-27(17-33)41(28)30;1-21-3-5-22(6-4-21)27(16-33)31(41)39-11-9-38(10-12-39)29-8-7-23(17-34-29)28-13-24(25-18-36-37(2)20-25)14-30-35-19-26(15-32)40(28)30;1-34-21-24(19-33-34)23-15-27(37-25(17-30)20-32-29(37)16-23)22-7-8-28(31-18-22)36-11-9-35(10-12-36)13-14-40(38,39)26-5-3-2-4-6-26;1-32-6-5-22(31-32)18-34-7-9-35(10-8-34)25-4-3-19(14-28-25)24-11-20(21-15-30-33(2)17-21)12-26-29-16-23(13-27)36(24)26/h5-8,13-15,17-20,31H,9-12H2,1-4H3;2*5-9,14-16,18-21,31H,10-13H2,1-4H3;3-8,13-14,17-20,27H,9-12,16,33H2,1-2H3;2-8,15-16,18-21H,9-14H2,1H3;3-6,11-12,14-17H,7-10,18H2,1-2H3/t;2*31-;;;/m.10.../s1
InChIKeyIVKRHNNXNUXEKS-JXGVYDMQSA-N
XLogP21.28
TPSA625.66 Ų
H-Bond Donors1
H-Bond Acceptors56
Rotatable Bonds36
Heavy Atoms244
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003273.90
LogP ≤ 521.28
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 1056

Analyze 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(4R)-4-[3-[3-(cyclopropylmethylsulfonyl)phenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(5,6-dimethylbenzimidazol-1-yl)pentan-2-one;(4R)-1-[4-(difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]-5-(3,5-difluorophenyl)-4-[3-(3-ethyl-4-fluorophenyl)-2-pyridinyl]pentan-2-one;(4R)-5-(3,5-difluorophenyl)-4-[3-(3-ethyl-4-fluorophenyl)-2-pyridinyl]-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[5,4-c]pyridin-1-yl]pentan-2-one;(4R)-5-(3,5-difluorophenyl)-4-[5-(4-methylphenyl)pyrimidin-4-yl]-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]pentan-2-one
CID 157143465
(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-1-[4-(cyclopenten-1-yl)-3-(trifluoromethyl)pyrazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[5,4-c]pyridin-1-yl]pentan-2-one;7-[(4R)-4-[3-(3-acetylphenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-2-oxopentyl]-3-methyl-1,5-dihydrocyclopenta[b]pyridin-2-one;(4R)-4-[3-[3-(cyclopropylmethylsulfonyl)phenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(5,6-dimethylbenzimidazol-1-yl)pentan-2-one;(4R)-5-(3,5-difluorophenyl)-4-[5-(4-methylphenyl)pyrimidin-4-yl]-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]pentan-2-one
CID 159180446
1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[3,4-d]pyridazine-4-carboxamide;1-(4-fluorophenyl)-N-[(2-methylsulfonyl-4-pyridinyl)methyl]pyrazolo[3,4-d]pyridazine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[3,4-d]pyridazine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(6-methylsulfonyl-3-pyridinyl)propyl]pyrazolo[3,4-d]pyridazine-4-carboxamide;1-(4-fluorophenyl)-N-[[3-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidine-4-carboxamide
CID 159322771
N-[3-[2-[5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-2H-pyrazolo[3,4-b]pyridin-3-yl]-3H-imidazo[4,5-c]pyridin-7-yl]-5-fluorophenyl]-N',N'-dimethylethane-1,2-diamine;N-[5-[3-[7-[3-[2-(dimethylamino)ethylamino]-5-fluorophenyl]-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]cyclohexanecarboxamide;N-[5-[3-[7-[3-fluoro-5-(2-methylsulfonylethyl)phenyl]-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]-3-methylbutanamide;N-[5-[3-[7-[3-fluoro-5-(2-methylsulfonylethyl)phenyl]-3H-imidazo[4,5-c]pyridin-2-yl]-2H-pyrazolo[3,4-b]pyridin-5-yl]-3-pyridinyl]propanamide
CID 159855630
4-(aminomethyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;4-(3-cyclopropyl-3-oxopropyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;4-(2-cyclopropylsulfonylethyl)-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-4-[(2-oxopyrrolidin-1-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-6-one;2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-6-oxo-7H-pyrrolo[2,3-d]pyrimidine-4-carbonitrile;2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-5,5-dimethyl-4-(4,4,4-trifluorobutyl)-7H-pyrrolo[2,3-d]pyrimidin-6-one;2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]-4-iodo-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one
CID 161169238
(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-1-[4-(difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-(3-acetyl-4-fluorophenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[5,4-c]pyridin-1-yl]pentan-2-one;7-[(4R)-4-[3-(3-acetylphenyl)-2-pyridinyl]-5-(3,5-difluorophenyl)-2-oxopentyl]-3-methyl-1,5-dihydrocyclopenta[b]pyridin-2-one;(4R)-4-[3-[3-(cyclopropylmethylsulfonyl)phenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-(5,6-dimethylbenzimidazol-1-yl)pentan-2-one;(4R)-5-(3,5-difluorophenyl)-4-[5-(4-methylphenyl)pyrimidin-4-yl]-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]pentan-2-one
CID 161819452
(2S,4R)-N-[[4-[5-(1,1-difluoroethyl)pyrazin-2-yl]-2-pyridinyl]methyl]-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidine-2-carboxamide;(2S,4R)-N-[[3-[4-(1,1-difluoroethyl)pyrazol-1-yl]-5-fluorophenyl]methyl]-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidine-2-carboxamide;(2R,3S)-N-[[3-[2-(1,1-difluoroethyl)pyrimidin-5-yl]-5-fluorophenyl]methyl]-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidine-2-carboxamide;(2S,4R)-N-[[2-[2-(1,1-difluoroethyl)pyrimidin-5-yl]-4-pyridinyl]methyl]-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidine-2-carboxamide
CID 163905215
4-[8-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]imidazo[1,2-a]pyridin-5-yl]benzamide;N-[3-fluoro-4-(4-propan-2-ylpiperazin-1-yl)phenyl]-5-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-8-amine;4-[8-(4-methylsulfonylanilino)imidazo[1,2-a]pyridin-5-yl]-1H-pyridin-2-one;N-(4-morpholin-4-ylphenyl)-5-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-8-amine
CID 157087300
4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]benzonitrile;N-[3-[4-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]-1-methylpyrazol-3-yl]phenyl]benzamide;5-[8-[3-(dimethylamino)anilino]imidazo[1,2-a]pyrazin-3-yl]-1H-pyridin-2-one;3-N,3-N-dimethyl-1-N-[3-(3-methylsulfonylphenyl)imidazo[1,2-a]pyrazin-8-yl]benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-(3-pyridin-4-ylimidazo[1,2-a]pyrazin-8-yl)benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-(3-quinolin-7-ylimidazo[1,2-a]pyrazin-8-yl)benzene-1,3-diamine;3-N,3-N-dimethyl-1-N-(3-thiophen-2-ylimidazo[1,2-a]pyrazin-8-yl)benzene-1,3-diamine
CID 157097896
5-(6-amino-3-pyridinyl)-N-(4-methylsulfonylphenyl)imidazo[1,2-a]pyridin-8-amine;N-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]-5-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-8-amine;4-[8-[3-fluoro-4-(4-propan-2-ylpiperazin-1-yl)anilino]imidazo[1,2-a]pyridin-5-yl]benzamide;4-[8-(4-morpholin-4-ylanilino)imidazo[1,2-a]pyridin-5-yl]benzamide
CID 157815211
6-(difluoromethyl)-3-[6-(2,3-dihydroindol-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine;1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-2,3-dihydroindole-3-carboxamide;N-[[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]-4-methylpyrrolidin-3-yl]methyl]methanesulfonamide;N-[2-[1-[6-[6-(difluoromethyl)imidazo[1,2-b]pyridazin-3-yl]pyrimidin-4-yl]pyrrolidin-3-yl]ethyl]methanesulfonamide;6-(difluoromethyl)-3-[6-(3-methylsulfonylpiperidin-1-yl)pyrimidin-4-yl]imidazo[1,2-b]pyridazine
CID 157859923
4-[6-[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]imidazo[1,2-a]pyrazin-3-yl]benzonitrile;4-[6-[4-(4-methyl-3-oxopiperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile;4-[6-[4-(4-methylpiperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyrazin-3-yl]benzonitrile;4-[6-[4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile;4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile;4-[6-[4-(piperazine-1-carbonyl)phenyl]imidazo[1,2-b]pyridazin-3-yl]benzonitrile
CID 158040848

Frequently Asked Questions

What is the IUPAC name of 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile?
The IUPAC name of 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile (CID 163662283) is 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile.
What is the SMILES notation for 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile?
The canonical SMILES for 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile is Cc1cc(C(C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)ccc1F.Cc1ccc(C(CN)C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)cc1.Cc1cccc([C@@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cc1cccc([C@H](C(=O)N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cc5ncc(C#N)n45)cn3)CC2)N(C)C)c1.Cn1cc(-c2cc(-c3ccc(N4CCN(CCS(=O)(=O)c5ccccc5)CC4)nc3)n3c(C#N)cnc3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(Cc5ccn(C)n5)CC4)nc3)n3c(C#N)cnc3c2)cn1.
What is the InChIKey of 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile?
The InChIKey is IVKRHNNXNUXEKS-JXGVYDMQSA-N. The full InChI is InChI=1S/C32H32FN9O.2C32H33N9O.C31H31N9O.C29H28N8O2S.C26H26N10/c1-21-13-22(5-7-27(21)33)31(38(2)3)32(43)41-11-9-40(10-12-41)29-8-6-23(17-35-29)28-14-24(25-18-37-39(4)20-25)15-30-36-19-26(16-34)42(28)30;2*1-22-6-5-7-23(14-22)31(37(2)3)32(42)40-12-10-39(11-13-40)29-9-8-24(18-34-29)28-15-25(26-19-36-38(4)21-26)16-30-35-20-27(17-33)41(28)30;1-21-3-5-22(6-4-21)27(16-33)31(41)39-11-9-38(10-12-39)29-8-7-23(17-34-29)28-13-24(25-18-36-37(2)20-25)14-30-35-19-26(15-32)40(28)30;1-34-21-24(19-33-34)23-15-27(37-25(17-30)20-32-29(37)16-23)22-7-8-28(31-18-22)36-11-9-35(10-12-36)13-14-40(38,39)26-5-3-2-4-6-26;1-32-6-5-22(31-32)18-34-7-9-35(10-8-34)25-4-3-19(14-28-25)24-11-20(21-15-30-33(2)17-21)12-26-29-16-23(13-27)36(24)26/h5-8,13-15,17-20,31H,9-12H2,1-4H3;2*5-9,14-16,18-21,31H,10-13H2,1-4H3;3-8,13-14,17-20,27H,9-12,16,33H2,1-2H3;2-8,15-16,18-21H,9-14H2,1H3;3-6,11-12,14-17H,7-10,18H2,1-2H3/t;2*31-;;;/m.10.../s1.
What are the key properties of 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile?
5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile has a molecular weight of 3273.90 g/mol, XLogP of 21.28, 36 rotatable bonds, 1 hydrogen bond donors, and 56 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[6-[4-[3-amino-2-(4-methylphenyl)propanoyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(benzenesulfonyl)ethyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[2-(dimethylamino)-2-(4-fluoro-3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2S)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;5-[6-[4-[(2R)-2-(dimethylamino)-2-(3-methylphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-carbonitrile;7-(1-methylpyrazol-4-yl)-5-[6-[4-[(1-methylpyrazol-3-yl)methyl]piperazin-1-yl]-3-pyridinyl]imidazo[1,2-a]pyridine-3-carbonitrile is sourced from PubChem (CID 163662283), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).