N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

C123H128F18N40O12S2 — CID 163664366

IUPACN-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cc(-c2ccns2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C)C3CC3)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1nscc1-c1cc(C)n2ncc(C(=O)N[C@@H](C3CC3)C(F)(F)F)c2n1
InChIInChI=1S/4C18H19F3N6O2.C18H22N6O2.C17H16F3N5OS.C16H14F3N5OS/c2*1-8(2)17-25-14(26-29-17)12-6-9(3)27-15(23-12)11(7-22-27)16(28)24-13(10-4-5-10)18(19,20)21;2*1-8(2)16-25-26-17(29-16)12-6-9(3)27-14(23-12)11(7-22-27)15(28)24-13(10-4-5-10)18(19,20)21;1-9(2)18-22-15(23-26-18)14-7-10(3)24-16(21-14)13(8-19-24)17(25)20-11(4)12-5-6-12;1-8-5-13(12-7-27-24-9(12)2)22-15-11(6-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20;1-8-6-11(12-4-5-21-26-12)22-14-10(7-20-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4*6-8,10,13H,4-5H2,1-3H3,(H,24,28);7-9,11-12H,5-6H2,1-4H3,(H,20,25);5-7,10,14H,3-4H2,1-2H3,(H,23,26);4-7,9,13H,2-3H2,1H3,(H,23,25)/t4*13-;11-;14-;/m101000./s1
InChIKeyIXDABNSUSDAERJ-GQCNUJMXSA-N
MW2764.74 g/mol
LogP22.64
Rot. Bonds33

About N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 163664366) has the molecular formula C123H128F18N40O12S2 and a molecular weight of 2764.74 g/mol. Its IUPAC name is N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

Compound NameN-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
PubChem CID163664366
Molecular FormulaC123H128F18N40O12S2
Molecular Weight2764.74 g/mol
Exact Mass2762.98
IUPAC NameN-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILESCc1cc(-c2ccns2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C)C3CC3)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1nscc1-c1cc(C)n2ncc(C(=O)N[C@@H](C3CC3)C(F)(F)F)c2n1
InChIInChI=1S/4C18H19F3N6O2.C18H22N6O2.C17H16F3N5OS.C16H14F3N5OS/c2*1-8(2)17-25-14(26-29-17)12-6-9(3)27-15(23-12)11(7-22-27)16(28)24-13(10-4-5-10)18(19,20)21;2*1-8(2)16-25-26-17(29-16)12-6-9(3)27-14(23-12)11(7-22-27)15(28)24-13(10-4-5-10)18(19,20)21;1-9(2)18-22-15(23-26-18)14-7-10(3)24-16(21-14)13(8-19-24)17(25)20-11(4)12-5-6-12;1-8-5-13(12-7-27-24-9(12)2)22-15-11(6-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20;1-8-6-11(12-4-5-21-26-12)22-14-10(7-20-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4*6-8,10,13H,4-5H2,1-3H3,(H,24,28);7-9,11-12H,5-6H2,1-4H3,(H,20,25);5-7,10,14H,3-4H2,1-2H3,(H,23,26);4-7,9,13H,2-3H2,1H3,(H,23,25)/t4*13-;11-;14-;/m101000./s1
InChIKeyIXDABNSUSDAERJ-GQCNUJMXSA-N
XLogP22.64
TPSA635.41 Ų
H-Bond Donors7
H-Bond Acceptors47
Rotatable Bonds33
Heavy Atoms195
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002764.74
LogP ≤ 522.64
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1047

Analyze N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

CID 159001300
CID 159001300
CID 160716108
CID 160716108
N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(3-methyl-1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(4-methyl-1,2-oxazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-[2-(trifluoromethyl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-[2-(trifluoromethyl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-[4-(trifluoromethyl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-[4-(trifluoromethyl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 163430993
N-[5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-4-methylthiophen-2-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[5-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-1,3,4-oxadiazol-2-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[5-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-1,3,4-thiadiazol-2-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[5-[2-(1H-pyrazol-4-yl)ethoxymethyl]thiophen-2-yl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;hydrochloride
CID 167541061

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The IUPAC name of N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 163664366) is N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide.
What is the SMILES notation for N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The canonical SMILES for N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is Cc1cc(-c2ccns2)nc2c(C(=O)NC(C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2nnc(C(C)C)o2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C)C3CC3)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@@H](C3CC3)C(F)(F)F)cnn12.Cc1cc(-c2noc(C(C)C)n2)nc2c(C(=O)N[C@H](C3CC3)C(F)(F)F)cnn12.Cc1nscc1-c1cc(C)n2ncc(C(=O)N[C@@H](C3CC3)C(F)(F)F)c2n1.
What is the InChIKey of N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The InChIKey is IXDABNSUSDAERJ-GQCNUJMXSA-N. The full InChI is InChI=1S/4C18H19F3N6O2.C18H22N6O2.C17H16F3N5OS.C16H14F3N5OS/c2*1-8(2)17-25-14(26-29-17)12-6-9(3)27-15(23-12)11(7-22-27)16(28)24-13(10-4-5-10)18(19,20)21;2*1-8(2)16-25-26-17(29-16)12-6-9(3)27-14(23-12)11(7-22-27)15(28)24-13(10-4-5-10)18(19,20)21;1-9(2)18-22-15(23-26-18)14-7-10(3)24-16(21-14)13(8-19-24)17(25)20-11(4)12-5-6-12;1-8-5-13(12-7-27-24-9(12)2)22-15-11(6-21-25(8)15)16(26)23-14(10-3-4-10)17(18,19)20;1-8-6-11(12-4-5-21-26-12)22-14-10(7-20-24(8)14)15(25)23-13(9-2-3-9)16(17,18)19/h4*6-8,10,13H,4-5H2,1-3H3,(H,24,28);7-9,11-12H,5-6H2,1-4H3,(H,20,25);5-7,10,14H,3-4H2,1-2H3,(H,23,26);4-7,9,13H,2-3H2,1H3,(H,23,25)/t4*13-;11-;14-;/m101000./s1.
What are the key properties of N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide?
N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2764.74 g/mol, XLogP of 22.64, 33 rotatable bonds, 7 hydrogen bond donors, and 47 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-cyclopropylethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(3-methyl-1,2-thiazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,2,4-oxadiazol-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-7-methyl-5-(5-propan-2-yl-1,3,4-oxadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-(1-cyclopropyl-2,2,2-trifluoroethyl)-7-methyl-5-(1,2-thiazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 163664366), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).