(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide

C240H240F15N39O32S5 — CID 163700139

IUPAC(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
SMILESC=C1CCC(N2Cc3cc(N4CC(OCCOc5ccc(-c6cnc7[nH]cc(C(=O)c8c(F)ccc(NS(=O)(=O)N9CC[C@@H](F)C9)c8F)c7c6)cc5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CC5(CN(CC6CC7(C6)CN(c6ccc(-c8cnc9[nH]cc(C(=O)c%10c(F)ccc(NS(=O)(=O)N%11CC[C@@H](F)C%11)c%10F)c9c8)cc6)C7)C5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCC(O[C@@H]5CCC[C@@H](Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)C5)CC4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCN(C5CCC(Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)CC5)CC4)cc(OC)c3C2=O)C(=O)N1.O=C1CCC(N2Cc3cc(C4CCN(CC5CC6(C5)CN(c5ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc5)C6)CC4)ccc3C2=O)C(=O)N1
InChIInChI=1S/C50H50F3N9O5S.C49H51F3N8O7S.C49H49F3N8O6S.C49H50F3N7O7S.C43H40F3N7O7S/c1-29-2-11-42(47(64)56-29)62-21-33-14-36(7-8-37(33)48(62)65)60-27-50(28-60)23-58(24-50)20-30-16-49(17-30)25-59(26-49)35-5-3-31(4-6-35)32-15-38-39(19-55-46(38)54-18-32)45(63)43-40(52)9-10-41(44(43)53)57-68(66,67)61-13-12-34(51)22-61;1-28-3-14-41(48(62)55-28)60-26-31-21-34(23-42(66-2)43(31)49(60)63)58-19-17-57(18-20-58)33-6-10-36(11-7-33)67-35-8-4-29(5-9-35)30-22-37-38(25-54-47(37)53-24-30)46(61)44-39(51)12-13-40(45(44)52)56-68(64,65)59-16-15-32(50)27-59;50-34-13-16-59(25-34)67(65,66)56-40-8-7-39(51)43(44(40)52)45(62)38-22-54-46-37(38)18-32(21-53-46)29-1-4-35(5-2-29)58-26-49(27-58)19-28(20-49)23-57-14-11-30(12-15-57)31-3-6-36-33(17-31)24-60(48(36)64)41-9-10-42(61)55-47(41)63;1-28-5-14-43(48(61)55-28)59-26-31-21-33(8-11-38(31)49(59)62)57-18-16-35(17-19-57)66-37-4-2-3-36(23-37)65-34-9-6-29(7-10-34)30-22-39-40(25-54-47(39)53-24-30)46(60)44-41(51)12-13-42(45(44)52)56-67(63,64)58-20-15-32(50)27-58;1-24-2-11-37(42(55)49-24)53-20-27-16-29(5-8-32(27)43(53)56)51-22-31(23-51)60-15-14-59-30-6-3-25(4-7-30)26-17-33-34(19-48-41(33)47-18-26)40(54)38-35(45)9-10-36(39(38)46)50-61(57,58)52-13-12-28(44)21-52/h3-10,14-15,18-19,30,34,42,57H,1-2,11-13,16-17,20-28H2,(H,54,55)(H,56,64);4-5,8-9,12-13,21-25,32-33,36,41,56H,1,3,6-7,10-11,14-20,26-27H2,2H3,(H,53,54)(H,55,62);1-8,17-18,21-22,28,30,34,41,56H,9-16,19-20,23-27H2,(H,53,54)(H,55,61,63);6-13,21-22,24-25,32,35-37,43,56H,1-5,14-20,23,26-27H2,(H,53,54)(H,55,61);3-10,16-19,28,31,37,50H,1-2,11-15,20-23H2,(H,47,48)(H,49,55)/t34-,42?;32-,33?,36?,41?;34-,41?;32-,36-,37-,43?;28-,37?/m11111/s1
InChIKeyKAHKJIPPGCWPPC-RWIUDGJTSA-N
MW4628.11 g/mol
LogP32.27
Rot. Bonds59

About (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide

(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide (PubChem CID 163700139) has the molecular formula C240H240F15N39O32S5 and a molecular weight of 4628.11 g/mol. Its IUPAC name is (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide.

Molecular Properties

Compound Name(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
PubChem CID163700139
Molecular FormulaC240H240F15N39O32S5
Molecular Weight4628.11 g/mol
Exact Mass4624.67
IUPAC Name(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
SMILESC=C1CCC(N2Cc3cc(N4CC(OCCOc5ccc(-c6cnc7[nH]cc(C(=O)c8c(F)ccc(NS(=O)(=O)N9CC[C@@H](F)C9)c8F)c7c6)cc5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CC5(CN(CC6CC7(C6)CN(c6ccc(-c8cnc9[nH]cc(C(=O)c%10c(F)ccc(NS(=O)(=O)N%11CC[C@@H](F)C%11)c%10F)c9c8)cc6)C7)C5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCC(O[C@@H]5CCC[C@@H](Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)C5)CC4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCN(C5CCC(Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)CC5)CC4)cc(OC)c3C2=O)C(=O)N1.O=C1CCC(N2Cc3cc(C4CCN(CC5CC6(C5)CN(c5ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc5)C6)CC4)ccc3C2=O)C(=O)N1
InChIInChI=1S/C50H50F3N9O5S.C49H51F3N8O7S.C49H49F3N8O6S.C49H50F3N7O7S.C43H40F3N7O7S/c1-29-2-11-42(47(64)56-29)62-21-33-14-36(7-8-37(33)48(62)65)60-27-50(28-60)23-58(24-50)20-30-16-49(17-30)25-59(26-49)35-5-3-31(4-6-35)32-15-38-39(19-55-46(38)54-18-32)45(63)43-40(52)9-10-41(44(43)53)57-68(66,67)61-13-12-34(51)22-61;1-28-3-14-41(48(62)55-28)60-26-31-21-34(23-42(66-2)43(31)49(60)63)58-19-17-57(18-20-58)33-6-10-36(11-7-33)67-35-8-4-29(5-9-35)30-22-37-38(25-54-47(37)53-24-30)46(61)44-39(51)12-13-40(45(44)52)56-68(64,65)59-16-15-32(50)27-59;50-34-13-16-59(25-34)67(65,66)56-40-8-7-39(51)43(44(40)52)45(62)38-22-54-46-37(38)18-32(21-53-46)29-1-4-35(5-2-29)58-26-49(27-58)19-28(20-49)23-57-14-11-30(12-15-57)31-3-6-36-33(17-31)24-60(48(36)64)41-9-10-42(61)55-47(41)63;1-28-5-14-43(48(61)55-28)59-26-31-21-33(8-11-38(31)49(59)62)57-18-16-35(17-19-57)66-37-4-2-3-36(23-37)65-34-9-6-29(7-10-34)30-22-39-40(25-54-47(39)53-24-30)46(60)44-41(51)12-13-42(45(44)52)56-67(63,64)58-20-15-32(50)27-58;1-24-2-11-37(42(55)49-24)53-20-27-16-29(5-8-32(27)43(53)56)51-22-31(23-51)60-15-14-59-30-6-3-25(4-7-30)26-17-33-34(19-48-41(33)47-18-26)40(54)38-35(45)9-10-36(39(38)46)50-61(57,58)52-13-12-28(44)21-52/h3-10,14-15,18-19,30,34,42,57H,1-2,11-13,16-17,20-28H2,(H,54,55)(H,56,64);4-5,8-9,12-13,21-25,32-33,36,41,56H,1,3,6-7,10-11,14-20,26-27H2,2H3,(H,53,54)(H,55,62);1-8,17-18,21-22,28,30,34,41,56H,9-16,19-20,23-27H2,(H,53,54)(H,55,61,63);6-13,21-22,24-25,32,35-37,43,56H,1-5,14-20,23,26-27H2,(H,53,54)(H,55,61);3-10,16-19,28,31,37,50H,1-2,11-15,20-23H2,(H,47,48)(H,49,55)/t34-,42?;32-,33?,36?,41?;34-,41?;32-,36-,37-,43?;28-,37?/m11111/s1
InChIKeyKAHKJIPPGCWPPC-RWIUDGJTSA-N
XLogP32.27
TPSA824.46 Ų
H-Bond Donors15
H-Bond Acceptors46
Rotatable Bonds59
Heavy Atoms331
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004628.11
LogP ≤ 532.27
H-Bond Donors ≤ 515
H-Bond Acceptors ≤ 1046

Analyze (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide with MolForge

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Related Compounds

(3R)-N-[3-[5-[4-[4-[4-[2-(2,6-dioxopiperidin-3-yl)-7-methoxy-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 166841178
(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 163799145
(3R)-N-[3-[5-[4-[(1R)-3-[1-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 166841343
(3R)-N-[3-[5-[4-[(1R,3S)-3-[1-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclopentyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 166841232
(3R)-N-[3-[5-[4-[4-[[3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]oxy]cyclobutyl]methyl]piperazin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 166841196
(3R)-N-[3-[5-[4-[4-[[4-[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]piperidin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-4-fluoro-2-methoxyphenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 162741702
(3R)-N-[3-[5-[4-[4-[[3-[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-5-yl]azetidin-1-yl]methyl]piperidin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 162741564
(3R)-N-[3-[5-[6-[4-[[4-[2-(2,6-dioxopiperidin-3-yl)-7-methoxy-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]piperidin-1-yl]-3-pyridinyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 162742158
(3R)-N-[3-[5-[4-[(1R,5S)-6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-3-azabicyclo[3.1.0]hexan-3-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 167010439
(3R)-N-[3-[5-[4-[4-[[4-[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]piperidin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-hydroxypyrrolidine-1-sulfonamide
CID 167398784
(3R)-N-[3-[5-[4-[(2R,4R)-4-[[4-[2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-methylpiperidin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 167399004
(3R)-N-[3-[5-[4-[(2S,4S)-4-[[4-[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-methylpiperidin-1-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CID 162742214

Frequently Asked Questions

What is the IUPAC name of (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide?
The IUPAC name of (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide (CID 163700139) is (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide.
What is the SMILES notation for (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide?
The canonical SMILES for (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide is C=C1CCC(N2Cc3cc(N4CC(OCCOc5ccc(-c6cnc7[nH]cc(C(=O)c8c(F)ccc(NS(=O)(=O)N9CC[C@@H](F)C9)c8F)c7c6)cc5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CC5(CN(CC6CC7(C6)CN(c6ccc(-c8cnc9[nH]cc(C(=O)c%10c(F)ccc(NS(=O)(=O)N%11CC[C@@H](F)C%11)c%10F)c9c8)cc6)C7)C5)C4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCC(O[C@@H]5CCC[C@@H](Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)C5)CC4)ccc3C2=O)C(=O)N1.C=C1CCC(N2Cc3cc(N4CCN(C5CCC(Oc6ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc6)CC5)CC4)cc(OC)c3C2=O)C(=O)N1.O=C1CCC(N2Cc3cc(C4CCN(CC5CC6(C5)CN(c5ccc(-c7cnc8[nH]cc(C(=O)c9c(F)ccc(NS(=O)(=O)N%10CC[C@@H](F)C%10)c9F)c8c7)cc5)C6)CC4)ccc3C2=O)C(=O)N1.
What is the InChIKey of (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide?
The InChIKey is KAHKJIPPGCWPPC-RWIUDGJTSA-N. The full InChI is InChI=1S/C50H50F3N9O5S.C49H51F3N8O7S.C49H49F3N8O6S.C49H50F3N7O7S.C43H40F3N7O7S/c1-29-2-11-42(47(64)56-29)62-21-33-14-36(7-8-37(33)48(62)65)60-27-50(28-60)23-58(24-50)20-30-16-49(17-30)25-59(26-49)35-5-3-31(4-6-35)32-15-38-39(19-55-46(38)54-18-32)45(63)43-40(52)9-10-41(44(43)53)57-68(66,67)61-13-12-34(51)22-61;1-28-3-14-41(48(62)55-28)60-26-31-21-34(23-42(66-2)43(31)49(60)63)58-19-17-57(18-20-58)33-6-10-36(11-7-33)67-35-8-4-29(5-9-35)30-22-37-38(25-54-47(37)53-24-30)46(61)44-39(51)12-13-40(45(44)52)56-68(64,65)59-16-15-32(50)27-59;50-34-13-16-59(25-34)67(65,66)56-40-8-7-39(51)43(44(40)52)45(62)38-22-54-46-37(38)18-32(21-53-46)29-1-4-35(5-2-29)58-26-49(27-58)19-28(20-49)23-57-14-11-30(12-15-57)31-3-6-36-33(17-31)24-60(48(36)64)41-9-10-42(61)55-47(41)63;1-28-5-14-43(48(61)55-28)59-26-31-21-33(8-11-38(31)49(59)62)57-18-16-35(17-19-57)66-37-4-2-3-36(23-37)65-34-9-6-29(7-10-34)30-22-39-40(25-54-47(39)53-24-30)46(60)44-41(51)12-13-42(45(44)52)56-67(63,64)58-20-15-32(50)27-58;1-24-2-11-37(42(55)49-24)53-20-27-16-29(5-8-32(27)43(53)56)51-22-31(23-51)60-15-14-59-30-6-3-25(4-7-30)26-17-33-34(19-48-41(33)47-18-26)40(54)38-35(45)9-10-36(39(38)46)50-61(57,58)52-13-12-28(44)21-52/h3-10,14-15,18-19,30,34,42,57H,1-2,11-13,16-17,20-28H2,(H,54,55)(H,56,64);4-5,8-9,12-13,21-25,32-33,36,41,56H,1,3,6-7,10-11,14-20,26-27H2,2H3,(H,53,54)(H,55,62);1-8,17-18,21-22,28,30,34,41,56H,9-16,19-20,23-27H2,(H,53,54)(H,55,61,63);6-13,21-22,24-25,32,35-37,43,56H,1-5,14-20,23,26-27H2,(H,53,54)(H,55,61);3-10,16-19,28,31,37,50H,1-2,11-15,20-23H2,(H,47,48)(H,49,55)/t34-,42?;32-,33?,36?,41?;34-,41?;32-,36-,37-,43?;28-,37?/m11111/s1.
What are the key properties of (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide?
(3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide has a molecular weight of 4628.11 g/mol, XLogP of 32.27, 59 rotatable bonds, 15 hydrogen bond donors, and 46 hydrogen bond acceptors.
Where does this data come from?
All data for (3R)-N-[2,4-difluoro-3-[5-[4-[4-[4-[7-methoxy-2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperazin-1-yl]cyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[2-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]azetidin-3-yl]oxyethoxy]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[6-[[2-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-2,6-diazaspiro[3.3]heptan-6-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[2,4-difluoro-3-[5-[4-[(1R,3R)-3-[1-[2-(6-methylidene-2-oxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-4-yl]oxycyclohexyl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl]-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[5-[4-[6-[[4-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]piperidin-1-yl]methyl]-2-azaspiro[3.3]heptan-2-yl]phenyl]-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide is sourced from PubChem (CID 163700139), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).