2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride

C122H171ClN22O24S4 — CID 163721078

About 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride

2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride (PubChem CID 163721078) has the molecular formula C122H171ClN22O24S4 and a molecular weight of 2493.56 g/mol. Its IUPAC name is 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride.

Molecular Properties

• Compound Name: 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride
• PubChem CID: 163721078
• Molecular Formula: C122H171ClN22O24S4
• Molecular Weight: 2493.56 g/mol
• Exact Mass: 2491.14
• IUPAC Name: 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride
• SMILES: CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C3(C)COC(C)(C)O3)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC1(C)OCC(C)(c2ccc(C(=O)O)c(N3CCC4(CC3)CC4)n2)O1.Cl
• InChI: InChI=1S/C28H39N5O5S.3C25H35N5O5S.C19H26N2O4.ClH/c1-25(2,3)32-39(35,36)22-9-7-8-21(30-22)31-24(34)19-10-11-20(27(6)18-37-26(4,5)38-27)29-23(19)33-16-14-28(12-13-28)15-17-33;3*1-23(2,3)29-36(34,35)20-7-5-6-19(27-20)28-22(32)17-8-9-18(24(4,33)16-31)26-21(17)30-14-12-25(10-11-25)13-15-30;1-17(2)24-12-18(3,25-17)14-5-4-13(16(22)23)15(20-14)21-10-8-19(6-7-19)9-11-21;/h7-11,32H,12-18H2,1-6H3,(H,30,31,34);3*5-9,29,31,33H,10-16H2,1-4H3,(H,27,28,32);4-5H,6-12H2,1-3H3,(H,22,23);1H/t;2*24-;;;/m.10.../s1
• InChIKey: RBYGAPMRGAFDGZ-LPUBMOSGSA-N
• XLogP: 14.92
• TPSA: 628.89 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 37
• Rotatable Bonds: 30
• Heavy Atoms: 173
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2493.56
LogP ≤ 5	14.92
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride?

The IUPAC name of 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride (CID 163721078) is 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride.

What is the SMILES notation for 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride?

The canonical SMILES for 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride is CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(C3(C)COC(C)(C)O3)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc([C@](C)(O)CO)nc2N2CCC3(CC2)CC3)n1.CC1(C)OCC(C)(c2ccc(C(=O)O)c(N3CCC4(CC3)CC4)n2)O1.Cl.

What is the InChIKey of 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride?

The InChIKey is RBYGAPMRGAFDGZ-LPUBMOSGSA-N. The full InChI is InChI=1S/C28H39N5O5S.3C25H35N5O5S.C19H26N2O4.ClH/c1-25(2,3)32-39(35,36)22-9-7-8-21(30-22)31-24(34)19-10-11-20(27(6)18-37-26(4,5)38-27)29-23(19)33-16-14-28(12-13-28)15-17-33;3*1-23(2,3)29-36(34,35)20-7-5-6-19(27-20)28-22(32)17-8-9-18(24(4,33)16-31)26-21(17)30-14-12-25(10-11-25)13-15-30;1-17(2)24-12-18(3,25-17)14-5-4-13(16(22)23)15(20-14)21-10-8-19(6-7-19)9-11-21;/h7-11,32H,12-18H2,1-6H3,(H,30,31,34);3*5-9,29,31,33H,10-16H2,1-4H3,(H,27,28,32);4-5H,6-12H2,1-3H3,(H,22,23);1H/t;2*24-;;;/m.10.../s1.

What are the key properties of 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride?

2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride has a molecular weight of 2493.56 g/mol, XLogP of 14.92, 30 rotatable bonds, 15 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(1,2-dihydroxypropan-2-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2R)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-[(2S)-1,2-dihydroxypropan-2-yl]pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-N-[6-(tert-butylsulfamoyl)-2-pyridinyl]-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxamide;2-(6-azaspiro[2.5]octan-6-yl)-6-(2,2,4-trimethyl-1,3-dioxolan-4-yl)pyridine-3-carboxylic acid;hydrochloride is sourced from PubChem (CID 163721078), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).